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GadW Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
GABA GABA_Ext CO2 DctR GadA GadB GadC GadE GadW GadX This Gensor Unit is not yet available HdeA HdeB L-glutamate L-glutamate_Ext MdtE MdtF Slp TolC YhiD a drug a drug_Ext gadAX gadAX_mRNA gadBC gadBC_mRNA gadE-mdtEF gadE-mdtEF_mRNA This Gensor Unit is not yet available This Gensor Unit is not yet available This Gensor Unit is not yet available This Gensor Unit is not yet available This Gensor Unit is not yet available This Gensor Unit is not yet available gadY gadY_mRNA hdeAB-yhiD hdeAB-yhiD_mRNA slp-dctR slp-dctR_mRNA TolC MdtE MdtF GadW


Gensor Unit       
Name: GadW
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:1902475 - L-alpha-amino acid transmembrane transport
GO:0015807 - L-amino acid transport
GO:0003333 - amino acid transmembrane transport
GO:0015721 - bile acid and bile salt transport
GO:0006974 - cellular response to DNA damage stimulus
GO:0071468 - cellular response to acidic pH
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cellular_component GO:0005829 - cytosol
GO:0005887 - integral component of plasma membrane
GO:0031226 - intrinsic component of plasma membrane
GO:0016020 - membrane
GO:0019867 - outer membrane
GO:0030288 - outer membrane-bounded periplasmic space
GO:0005886 - plasma membrane
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molecular_function GO:0003677 - DNA binding
GO:0003700 - DNA binding transcription factor activity
GO:0015179 - L-amino acid transmembrane transporter activity
GO:0015297 - antiporter activity
GO:0000986 - bacterial-type proximal promoter sequence-specific DNA binding
GO:0051087 - chaperone binding
GO:0015238 - drug transmembrane transporter activity
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Components: Show/Hide Components Table (43 more...)
Function Name Type
simple_molecule CO2 simple_molecule
protein DctR protein
simple_molecule GABA simple_molecule
simple_molecule GABA_Ext simple_molecule
protein GadA protein
protein GadB protein
protein GadC protein
protein GadE protein
protein GadW protein
protein GadX protein
protein HdeA protein
protein HdeB protein
simple_molecule L-glutamate simple_molecule
simple_molecule L-glutamate_Ext simple_molecule
protein MdtE protein
protein MdtF protein
protein RNA:IS183 protein
protein RcsB protein
complex RcsB-GadE complex
protein Slp protein
protein TolC protein
complex TolC-MdtE-MdtF complex
protein YhiD protein
simple_molecule drug simple_molecule
simple_molecule drug_Ext simple_molecule
gene gadAX gene
RNA gadAX_mRNA RNA
gene gadBC gene
RNA gadBC_mRNA RNA
gene gadE-mdtEF gene
RNA gadE-mdtEF_mRNA RNA
gene gadW gene
RNA gadW_mRNA RNA
gene gadX gene
gene gadXW gene
RNA gadXW_mRNA RNA
RNA gadX_mRNA RNA
gene gadY gene
RNA gadY_mRNA RNA
gene hdeAB-yhiD gene
RNA hdeAB-yhiD_mRNA RNA
gene slp-dctR gene
RNA slp-dctR_mRNA RNA


Reactions       
Showing 31 reactions
GadW GadW gadAX gadAX_mRNA
Name: gadAX -> gadAX_mRNA
Description: Transcription of transcription unit gadAX. Reaction activation by GadW. Reaction inhibition by GadW.
Type: transcription
Pathway Components: gadAX - GadW - GadW -> gadAX_mRNA
Components:
Function Name Type Evidence Reference(s)
activator GadW protein nd nd
inhibitor GadW protein nd nd
reactant gadAX gene nd nd
product gadAX_mRNA RNA nd nd
GadW GadW gadBC gadBC_mRNA
Name: gadBC -> gadBC_mRNA
Description: Transcription of transcription unit gadBC. Reaction activation by GadW. Reaction inhibition by GadW.
Type: transcription
Pathway Components: gadBC - GadW - GadW -> gadBC_mRNA
Components:
Function Name Type Evidence Reference(s)
activator GadW protein nd nd
inhibitor GadW protein nd nd
reactant gadBC gene nd nd
product gadBC_mRNA RNA nd nd
GadW gadE-mdtEF gadE-mdtEF_mRNA
Name: gadE-mdtEF -> gadE-mdtEF_mRNA
Description: Transcription of transcription unit gadE-mdtEF. Reaction activation by GadW.
Type: transcription
Pathway Components: gadE-mdtEF - GadW -> gadE-mdtEF_mRNA
Components:
Function Name Type Evidence Reference(s)
activator GadW protein nd nd
reactant gadE-mdtEF gene nd nd
product gadE-mdtEF_mRNA RNA nd nd
GadW gadW gadW_mRNA
Name: gadW -> gadW_mRNA
Description: Transcription of transcription unit gadW. Reaction inhibition by GadW.
Type: transcription
Pathway Components: gadW - GadW -> gadW_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor GadW protein nd nd
reactant gadW gene nd nd
product gadW_mRNA RNA nd nd
GadW gadX gadX_mRNA
Name: gadX -> gadX_mRNA
Description: Transcription of transcription unit gadX. Reaction inhibition by GadW.
Type: transcription
Pathway Components: gadX - GadW -> gadX_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor GadW protein nd nd
reactant gadX gene nd nd
product gadX_mRNA RNA nd nd
GadW gadXW gadXW_mRNA
Name: gadXW -> gadXW_mRNA
Description: Transcription of transcription unit gadXW. Reaction inhibition by GadW.
Type: transcription
Pathway Components: gadXW - GadW -> gadXW_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor GadW protein nd nd
reactant gadXW gene nd nd
product gadXW_mRNA RNA nd nd
GadW gadY gadY_mRNA
Name: gadY -> gadY_mRNA
Description: Transcription of transcription unit gadY. Reaction inhibition by GadW.
Type: transcription
Pathway Components: gadY - GadW -> gadY_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor GadW protein nd nd
reactant gadY gene nd nd
product gadY_mRNA RNA nd nd
GadW GadW hdeAB-yhiD hdeAB-yhiD_mRNA
Name: hdeAB-yhiD -> hdeAB-yhiD_mRNA
Description: Transcription of transcription unit hdeAB-yhiD. Reaction activation by GadW. Reaction inhibition by GadW.
Type: transcription
Pathway Components: hdeAB-yhiD - GadW - GadW -> hdeAB-yhiD_mRNA
Components:
Function Name Type Evidence Reference(s)
activator GadW protein nd nd
inhibitor GadW protein nd nd
reactant hdeAB-yhiD gene nd nd
product hdeAB-yhiD_mRNA RNA nd nd
GadW slp-dctR slp-dctR_mRNA
Name: slp-dctR -> slp-dctR_mRNA
Description: Transcription of transcription unit slp-dctR. Reaction inhibition by GadW.
Type: transcription
Pathway Components: slp-dctR - GadW -> slp-dctR_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor GadW protein nd nd
reactant slp-dctR gene nd nd
product slp-dctR_mRNA RNA nd nd
hdeAB-yhiD_mRNA HdeA
Name: hdeAB-yhiD_mRNA -> HdeA
Description: Translation of HdeA
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> HdeA
Components:
Function Name Type Evidence Reference(s)
product HdeA protein nd nd
reactant hdeAB-yhiD_mRNA RNA nd nd
hdeAB-yhiD_mRNA HdeB
Name: hdeAB-yhiD_mRNA -> HdeB
Description: Translation of HdeB
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> HdeB
Components:
Function Name Type Evidence Reference(s)
product HdeB protein nd nd
reactant hdeAB-yhiD_mRNA RNA nd nd
hdeAB-yhiD_mRNA YhiD
Name: hdeAB-yhiD_mRNA -> YhiD
Description: Translation of YhiD
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> YhiD
Components:
Function Name Type Evidence Reference(s)
product YhiD protein nd nd
reactant hdeAB-yhiD_mRNA RNA nd nd
gadY_mRNA RNA:IS183
Name: gadY_mRNA -> RNA:IS183
Description: Translation of RNA:IS183
Type: translation
Pathway Components: gadY_mRNA -> RNA:IS183
Components:
Function Name Type Evidence Reference(s)
product RNA:IS183 protein nd nd
reactant gadY_mRNA RNA nd nd
gadBC_mRNA GadB
Name: gadBC_mRNA -> GadB
Description: Translation of GadB
Type: translation
Pathway Components: gadBC_mRNA -> GadB
Components:
Function Name Type Evidence Reference(s)
product GadB protein nd nd
reactant gadBC_mRNA RNA nd nd
GadA GadB L-glutamate GABA + CO2
Name: L-glutamate -> GABA + CO2
Description: Reaction transforming L-glutamate into GABA, CO2
Type: state transition
Pathway Components: L-glutamate - GadA - GadB -> GABA + CO2
Components:
Function Name Type Evidence Reference(s)
product CO2 simple_molecule nd nd
product GABA simple_molecule nd nd
catalyzer GadA protein nd nd
catalyzer GadB protein nd nd
reactant L-glutamate simple_molecule nd nd
gadBC_mRNA GadC
Name: gadBC_mRNA -> GadC
Description: Translation of GadC
Type: translation
Pathway Components: gadBC_mRNA -> GadC
Components:
Function Name Type Evidence Reference(s)
product GadC protein nd nd
reactant gadBC_mRNA RNA nd nd
GadC L-glutamate_Ext + GABA_Ext L-glutamate + GABA
Name: L-glutamate_Ext + GABA_Ext -> L-glutamate + GABA
Description: Transport of L-glutamate_Ext, GABA_Ext through a bacterial membrane, leading to the presence of L-glutamate, GABA inside the cell.
Type: transport
Pathway Components: L-glutamate_Ext + GABA_Ext - GadC -> L-glutamate + GABA
Components:
Function Name Type Evidence Reference(s)
product GABA simple_molecule nd nd
reactant GABA_Ext simple_molecule nd nd
catalyzer GadC protein nd nd
product L-glutamate simple_molecule nd nd
reactant L-glutamate_Ext simple_molecule nd nd
gadX_mRNA GadX
Name: gadX_mRNA -> GadX
Description: Translation of GadX
Type: translation
Pathway Components: gadX_mRNA -> GadX
Components:
Function Name Type Evidence Reference(s)
product GadX protein nd nd
reactant gadX_mRNA RNA nd nd
gadE-mdtEF_mRNA GadE
Name: gadE-mdtEF_mRNA -> GadE
Description: Translation of GadE
Type: translation
Pathway Components: gadE-mdtEF_mRNA -> GadE
Components:
Function Name Type Evidence Reference(s)
product GadE protein nd nd
reactant gadE-mdtEF_mRNA RNA nd nd
RcsB + GadE RcsB-GadE
Name: RcsB + GadE -> RcsB-GadE
Description: Reaction transforming RcsB, GadE into RcsB-GadE
Type: state transition
Pathway Components: RcsB + GadE -> RcsB-GadE
Components:
Function Name Type Evidence Reference(s)
reactant GadE protein nd nd
reactant RcsB protein nd nd
product RcsB-GadE complex nd nd
gadE-mdtEF_mRNA MdtE
Name: gadE-mdtEF_mRNA -> MdtE
Description: Translation of MdtE
Type: translation
Pathway Components: gadE-mdtEF_mRNA -> MdtE
Components:
Function Name Type Evidence Reference(s)
product MdtE protein nd nd
reactant gadE-mdtEF_mRNA RNA nd nd
MdtF + MdtE + TolC TolC-MdtE-MdtF
Name: MdtF + MdtE + TolC -> TolC-MdtE-MdtF
Description: Reaction transforming MdtF, MdtE, TolC into TolC-MdtE-MdtF
Type: state transition
Pathway Components: MdtF + MdtE + TolC -> TolC-MdtE-MdtF
Components:
Function Name Type Evidence Reference(s)
reactant MdtE protein nd nd
reactant MdtF protein nd nd
reactant TolC protein nd nd
product TolC-MdtE-MdtF complex nd nd
TolC-MdtE-MdtF drug_Ext drug
Name: drug_Ext -> drug
Description: Transport of drug_Ext through a bacterial membrane, leading to the presence of drug inside the cell.
Type: transport
Pathway Components: drug_Ext - TolC-MdtE-MdtF -> drug
Components:
Function Name Type Evidence Reference(s)
catalyzer TolC-MdtE-MdtF complex nd nd
product drug simple_molecule nd nd
reactant drug_Ext simple_molecule nd nd
gadE-mdtEF_mRNA MdtF
Name: gadE-mdtEF_mRNA -> MdtF
Description: Translation of MdtF
Type: translation
Pathway Components: gadE-mdtEF_mRNA -> MdtF
Components:
Function Name Type Evidence Reference(s)
product MdtF protein nd nd
reactant gadE-mdtEF_mRNA RNA nd nd
gadW_mRNA GadW
Name: gadW_mRNA -> GadW
Description: Translation of GadW
Type: translation
Pathway Components: gadW_mRNA -> GadW
Components:
Function Name Type Evidence Reference(s)
product GadW protein nd nd
reactant gadW_mRNA RNA nd nd
slp-dctR_mRNA Slp
Name: slp-dctR_mRNA -> Slp
Description: Translation of Slp
Type: translation
Pathway Components: slp-dctR_mRNA -> Slp
Components:
Function Name Type Evidence Reference(s)
product Slp protein nd nd
reactant slp-dctR_mRNA RNA nd nd
slp-dctR_mRNA DctR
Name: slp-dctR_mRNA -> DctR
Description: Translation of DctR
Type: translation
Pathway Components: slp-dctR_mRNA -> DctR
Components:
Function Name Type Evidence Reference(s)
product DctR protein nd nd
reactant slp-dctR_mRNA RNA nd nd
gadXW_mRNA GadX
Name: gadXW_mRNA -> GadX
Description: Translation of GadX
Type: translation
Pathway Components: gadXW_mRNA -> GadX
Components:
Function Name Type Evidence Reference(s)
product GadX protein nd nd
reactant gadXW_mRNA RNA nd nd
gadXW_mRNA GadW
Name: gadXW_mRNA -> GadW
Description: Translation of GadW
Type: translation
Pathway Components: gadXW_mRNA -> GadW
Components:
Function Name Type Evidence Reference(s)
product GadW protein nd nd
reactant gadXW_mRNA RNA nd nd
gadAX_mRNA GadA
Name: gadAX_mRNA -> GadA
Description: Translation of GadA
Type: translation
Pathway Components: gadAX_mRNA -> GadA
Components:
Function Name Type Evidence Reference(s)
product GadA protein nd nd
reactant gadAX_mRNA RNA nd nd
gadAX_mRNA GadX
Name: gadAX_mRNA -> GadX
Description: Translation of GadX
Type: translation
Pathway Components: gadAX_mRNA -> GadX
Components:
Function Name Type Evidence Reference(s)
product GadX protein nd nd
reactant gadAX_mRNA RNA nd nd



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