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GadW Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          


Gensor Unit       
Name: GadW
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0071468 - cellular response to acidic pH
GO:0051082 - unfolded protein binding
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0003824 - catalytic activity
GO:0016020 - membrane
GO:0042597 - periplasmic space
GO:0019752 - carboxylic acid metabolic process
GO:0005737 - cytoplasm
GO:0016829 - lyase activity
GO:0055085 - transmembrane transport
GO:0046677 - response to antibiotic
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Components:
Function Name Type
RNA slp-dctR_mRNA RNA


Reactions       
Showing 30 reactions
gadAX gadAX_mRNA
Name: gadAX -> gadAX_mRNA
Description: Transcription of transcription unit gadAX; reaction activation by AdiY.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant gadAX gene nd nd
product gadAX_mRNA RNA nd nd
gadBC gadBC_mRNA
Name: gadBC -> gadBC_mRNA
Description: Transcription of transcription unit gadBC; reaction activation by AdiY.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant gadBC gene nd nd
product gadBC_mRNA RNA nd nd
gadE-mdtEF gadE-mdtEF_mRNA
Name: gadE-mdtEF -> gadE-mdtEF_mRNA
Description: Transcription of transcription unit gadE-mdtEF; reaction activation by EvgA-Phosphorylated.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant gadE-mdtEF gene nd nd
product gadE-mdtEF_mRNA RNA nd nd
gadW gadW_mRNA
Name: gadW -> gadW_mRNA
Description: Transcription of transcription unit gadW; reaction inhibition by GadW.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant gadW gene nd nd
product gadW_mRNA RNA nd nd
gadX gadX_mRNA
Name: gadX -> gadX_mRNA
Description: Transcription of transcription unit gadX; reaction activation by GadE.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product gadX_mRNA RNA nd nd
reactant gadX gene nd nd
gadXW gadXW_mRNA
Name: gadXW -> gadXW_mRNA
Description: Transcription of transcription unit gadXW; reaction activation by GadE.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product gadXW_mRNA RNA nd nd
reactant gadXW gene nd nd
gadY gadY_mRNA
Name: gadY -> gadY_mRNA
Description: Transcription of transcription unit gadY; reaction inhibition by GadW.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product gadY_mRNA RNA nd nd
reactant gadY gene nd nd
hdeAB-yhiD hdeAB-yhiD_mRNA
Name: hdeAB-yhiD -> hdeAB-yhiD_mRNA
Description: Transcription of transcription unit hdeAB-yhiD; reaction inhibition by FliZ.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product hdeAB-yhiD_mRNA RNA nd nd
reactant hdeAB-yhiD gene nd nd
slp-dctR slp-dctR_mRNA
Name: slp-dctR -> slp-dctR_mRNA
Description: Transcription of transcription unit slp-dctR; reaction activation by GadE-RcsB.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant slp-dctR gene nd nd
product slp-dctR_mRNA RNA nd nd
gadBC_mRNA GadC
Name: gadBC_mRNA -> GadC
Description: Translation of GadC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GadC protein nd nd
reactant gadBC_mRNA RNA nd nd
GABA_Ext + L-glutamate_Ext L-glutamate + GABA
Name: GABA_Ext + L-glutamate_Ext -> L-glutamate + GABA
Description: Transport of GABA_Ext, L-glutamate_Ext through a bacterial membrane, leading to the presence of L-glutamate, GABA inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant GABA_Ext simple molecule nd nd
product GABA simple molecule nd nd
product L-glutamate simple molecule nd nd
reactant L-glutamate_Ext simple molecule nd nd
gadE-mdtEF_mRNA MdtE
Name: gadE-mdtEF_mRNA -> MdtE
Description: Translation of MdtE
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadE-mdtEF_mRNA RNA nd nd
product MdtE protein nd nd
TolC + MdtE + MdtF TolC-MdtE-MdtF
Name: TolC + MdtE + MdtF -> TolC-MdtE-MdtF
Description: Reaction transforming TolC, MdtE, MdtF into TolC-MdtE-MdtF
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product TolC-MdtE-MdtF complex nd nd
reactant MdtF protein nd nd
reactant TolC protein nd nd
reactant MdtE protein nd nd
a drug_Ext a drug
Name: a drug_Ext -> a drug
Description: Transport of a drug_Ext through a bacterial membrane, leading to the presence of a drug inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant a drug_Ext simple molecule nd nd
product a drug simple molecule nd nd
slp-dctR_mRNA Slp
Name: slp-dctR_mRNA -> Slp
Description: Translation of Slp
Type: translation
Components:
Function Name Type Evidence Reference(s)
product Slp protein nd nd
reactant slp-dctR_mRNA RNA nd nd
slp-dctR_mRNA DctR
Name: slp-dctR_mRNA -> DctR
Description: Translation of DctR
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant slp-dctR_mRNA RNA nd nd
product DctR protein nd nd
gadE-mdtEF_mRNA GadE
Name: gadE-mdtEF_mRNA -> GadE
Description: Translation of GadE
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadE-mdtEF_mRNA RNA nd nd
product GadE protein nd nd
gadY_mRNA GadY small regulatory RNA
Name: gadY_mRNA -> GadY small regulatory RNA
Description: Translation of GadY small regulatory RNA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GadY small regulatory RNA RNA nd nd
reactant gadY_mRNA RNA nd nd
gadBC_mRNA GadB
Name: gadBC_mRNA -> GadB
Description: Translation of GadB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadBC_mRNA RNA nd nd
product GadB protein nd nd
L-glutamate CO2 + GABA
Name: L-glutamate -> CO2 + GABA
Description: Reaction transforming L-glutamate into CO2, GABA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product CO2 simple molecule nd nd
product GABA simple molecule nd nd
reactant L-glutamate simple molecule nd nd
gadXW_mRNA GadX
Name: gadXW_mRNA -> GadX
Description: Translation of GadX
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GadX protein nd nd
reactant gadXW_mRNA RNA nd nd
gadXW_mRNA GadW
Name: gadXW_mRNA -> GadW
Description: Translation of GadW
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadXW_mRNA RNA nd nd
product GadW protein nd nd
gadE-mdtEF_mRNA MdtF
Name: gadE-mdtEF_mRNA -> MdtF
Description: Translation of MdtF
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MdtF protein nd nd
reactant gadE-mdtEF_mRNA RNA nd nd
hdeAB-yhiD_mRNA HdeB
Name: hdeAB-yhiD_mRNA -> HdeB
Description: Translation of HdeB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant hdeAB-yhiD_mRNA RNA nd nd
product HdeB protein nd nd
hdeAB-yhiD_mRNA HdeA
Name: hdeAB-yhiD_mRNA -> HdeA
Description: Translation of HdeA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant hdeAB-yhiD_mRNA RNA nd nd
product HdeA protein nd nd
hdeAB-yhiD_mRNA YhiD
Name: hdeAB-yhiD_mRNA -> YhiD
Description: Translation of YhiD
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant hdeAB-yhiD_mRNA RNA nd nd
product YhiD protein nd nd
gadAX_mRNA GadA
Name: gadAX_mRNA -> GadA
Description: Translation of GadA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GadA protein nd nd
reactant gadAX_mRNA RNA nd nd
gadW_mRNA GadW
Name: gadW_mRNA -> GadW
Description: Translation of GadW
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GadW protein nd nd
reactant gadW_mRNA RNA nd nd
gadAX_mRNA GadX
Name: gadAX_mRNA -> GadX
Description: Translation of GadX
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadAX_mRNA RNA nd nd
product GadX protein nd nd
gadX_mRNA GadX
Name: gadX_mRNA -> GadX
Description: Translation of GadX
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadX_mRNA RNA nd nd
product GadX protein nd nd



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