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GadW Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
GABA GABA_Ext CO2 DctR GadA GadB GadC GadE GadW GadX This Gensor Unit is not yet available HdeA HdeB L-glutamate L-glutamate_Ext MdtE MdtF Slp TolC YhiD a drug a drug_Ext gadAX gadAX_mRNA gadBC gadBC_mRNA gadE-mdtEF gadE-mdtEF_mRNA This Gensor Unit is not yet available This Gensor Unit is not yet available This Gensor Unit is not yet available This Gensor Unit is not yet available This Gensor Unit is not yet available This Gensor Unit is not yet available gadY gadY_mRNA hdeAB-yhiD hdeAB-yhiD_mRNA slp-dctR slp-dctR_mRNA TolC MdtE MdtF GadW


Gensor Unit       
Name: GadW
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0071468 - cellular response to acidic pH
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0051082 - unfolded protein binding
GO:0016020 - membrane
GO:0003824 - catalytic activity
GO:0042597 - periplasmic space
GO:0016829 - lyase activity
GO:0019752 - carboxylic acid metabolic process
GO:0005737 - cytoplasm
GO:0003333 - amino acid transmembrane transport
GO:0055085 - transmembrane transport
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Components:
Function Name Type
RNA slp-dctR_mRNA RNA


Reactions       
Showing 30 reactions
gadAX gadAX_mRNA
Name: gadAX -> gadAX_mRNA
Description: Transcription of transcription unit gadAX; reaction activation by AdiY.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant gadAX gene nd nd
product gadAX_mRNA RNA nd nd
gadBC gadBC_mRNA
Name: gadBC -> gadBC_mRNA
Description: Transcription of transcription unit gadBC; reaction activation by AdiY.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant gadBC gene nd nd
product gadBC_mRNA RNA nd nd
gadE-mdtEF gadE-mdtEF_mRNA
Name: gadE-mdtEF -> gadE-mdtEF_mRNA
Description: Transcription of transcription unit gadE-mdtEF; reaction activation by EvgA-Phosphorylated.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant gadE-mdtEF gene nd nd
product gadE-mdtEF_mRNA RNA nd nd
gadW gadW_mRNA
Name: gadW -> gadW_mRNA
Description: Transcription of transcription unit gadW; reaction inhibition by GadW.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant gadW gene nd nd
product gadW_mRNA RNA nd nd
gadX gadX_mRNA
Name: gadX -> gadX_mRNA
Description: Transcription of transcription unit gadX; reaction activation by GadE.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product gadX_mRNA RNA nd nd
reactant gadX gene nd nd
gadXW gadXW_mRNA
Name: gadXW -> gadXW_mRNA
Description: Transcription of transcription unit gadXW; reaction activation by GadE.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product gadXW_mRNA RNA nd nd
reactant gadXW gene nd nd
gadY gadY_mRNA
Name: gadY -> gadY_mRNA
Description: Transcription of transcription unit gadY; reaction inhibition by GadW.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product gadY_mRNA RNA nd nd
reactant gadY gene nd nd
hdeAB-yhiD hdeAB-yhiD_mRNA
Name: hdeAB-yhiD -> hdeAB-yhiD_mRNA
Description: Transcription of transcription unit hdeAB-yhiD; reaction inhibition by FliZ.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product hdeAB-yhiD_mRNA RNA nd nd
reactant hdeAB-yhiD gene nd nd
slp-dctR slp-dctR_mRNA
Name: slp-dctR -> slp-dctR_mRNA
Description: Transcription of transcription unit slp-dctR; reaction activation by GadE-RcsB.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant slp-dctR gene nd nd
product slp-dctR_mRNA RNA nd nd
gadBC_mRNA GadC
Name: gadBC_mRNA -> GadC
Description: Translation of GadC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GadC protein nd nd
reactant gadBC_mRNA RNA nd nd
GABA_Ext + L-glutamate_Ext L-glutamate + GABA
Name: GABA_Ext + L-glutamate_Ext -> L-glutamate + GABA
Description: Transport of GABA_Ext, L-glutamate_Ext through a bacterial membrane, leading to the presence of L-glutamate, GABA inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant GABA_Ext simple molecule nd nd
product GABA simple molecule nd nd
product L-glutamate simple molecule nd nd
reactant L-glutamate_Ext simple molecule nd nd
gadE-mdtEF_mRNA MdtE
Name: gadE-mdtEF_mRNA -> MdtE
Description: Translation of MdtE
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadE-mdtEF_mRNA RNA nd nd
product MdtE protein nd nd
TolC + MdtE + MdtF TolC-MdtE-MdtF
Name: TolC + MdtE + MdtF -> TolC-MdtE-MdtF
Description: Reaction transforming TolC, MdtE, MdtF into TolC-MdtE-MdtF
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product TolC-MdtE-MdtF complex nd nd
reactant MdtF protein nd nd
reactant TolC protein nd nd
reactant MdtE protein nd nd
a drug_Ext a drug
Name: a drug_Ext -> a drug
Description: Transport of a drug_Ext through a bacterial membrane, leading to the presence of a drug inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant a drug_Ext simple molecule nd nd
product a drug simple molecule nd nd
slp-dctR_mRNA Slp
Name: slp-dctR_mRNA -> Slp
Description: Translation of Slp
Type: translation
Components:
Function Name Type Evidence Reference(s)
product Slp protein nd nd
reactant slp-dctR_mRNA RNA nd nd
slp-dctR_mRNA DctR
Name: slp-dctR_mRNA -> DctR
Description: Translation of DctR
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant slp-dctR_mRNA RNA nd nd
product DctR protein nd nd
gadE-mdtEF_mRNA GadE
Name: gadE-mdtEF_mRNA -> GadE
Description: Translation of GadE
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadE-mdtEF_mRNA RNA nd nd
product GadE protein nd nd
gadY_mRNA GadY small regulatory RNA
Name: gadY_mRNA -> GadY small regulatory RNA
Description: Translation of GadY small regulatory RNA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GadY small regulatory RNA RNA nd nd
reactant gadY_mRNA RNA nd nd
gadBC_mRNA GadB
Name: gadBC_mRNA -> GadB
Description: Translation of GadB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadBC_mRNA RNA nd nd
product GadB protein nd nd
L-glutamate CO2 + GABA
Name: L-glutamate -> CO2 + GABA
Description: Reaction transforming L-glutamate into CO2, GABA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product CO2 simple molecule nd nd
product GABA simple molecule nd nd
reactant L-glutamate simple molecule nd nd
gadXW_mRNA GadX
Name: gadXW_mRNA -> GadX
Description: Translation of GadX
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GadX protein nd nd
reactant gadXW_mRNA RNA nd nd
gadXW_mRNA GadW
Name: gadXW_mRNA -> GadW
Description: Translation of GadW
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadXW_mRNA RNA nd nd
product GadW protein nd nd
gadE-mdtEF_mRNA MdtF
Name: gadE-mdtEF_mRNA -> MdtF
Description: Translation of MdtF
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MdtF protein nd nd
reactant gadE-mdtEF_mRNA RNA nd nd
hdeAB-yhiD_mRNA HdeB
Name: hdeAB-yhiD_mRNA -> HdeB
Description: Translation of HdeB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant hdeAB-yhiD_mRNA RNA nd nd
product HdeB protein nd nd
hdeAB-yhiD_mRNA HdeA
Name: hdeAB-yhiD_mRNA -> HdeA
Description: Translation of HdeA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant hdeAB-yhiD_mRNA RNA nd nd
product HdeA protein nd nd
hdeAB-yhiD_mRNA YhiD
Name: hdeAB-yhiD_mRNA -> YhiD
Description: Translation of YhiD
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant hdeAB-yhiD_mRNA RNA nd nd
product YhiD protein nd nd
gadAX_mRNA GadA
Name: gadAX_mRNA -> GadA
Description: Translation of GadA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GadA protein nd nd
reactant gadAX_mRNA RNA nd nd
gadW_mRNA GadW
Name: gadW_mRNA -> GadW
Description: Translation of GadW
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GadW protein nd nd
reactant gadW_mRNA RNA nd nd
gadAX_mRNA GadX
Name: gadAX_mRNA -> GadX
Description: Translation of GadX
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadAX_mRNA RNA nd nd
product GadX protein nd nd
gadX_mRNA GadX
Name: gadX_mRNA -> GadX
Description: Translation of GadX
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadX_mRNA RNA nd nd
product GadX protein nd nd



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