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GadX Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
GABA GABA_Ext AmtB AsnB BtuB BtuC BtuD BtuF CO2 CadA CadB D-glu DctR ExbB ExbD GadA GadB GadC GadE GadW GadX This Gensor Unit is not yet available GlnK HdeA HdeB HdeD Hns L-asparagine asp L-glutamate L-glutamate_Ext L-glutamine L-lysine L-lysine_Ext Lon MdtE MdtF MurI This Gensor Unit is not yet available RpoS Slp TolC TonB UspE YbaS YbaT YhiD a drug a drug_Ext peptides Try ammonia ammonia_Ext ammonium ammonium_Ext asnB asnB_mRNA btuB-murI btuB-murI_mRNA cadBA cadBA_mRNA BioDex 1- BioDex 1-_Ext B12 B12_Ext Cbi Cbi_Ext PP gadAX gadAX_mRNA gadBC gadBC_mRNA gadE gadE-mdtEF gadE-mdtEF_mRNA gadE_mRNA This Gensor Unit is not yet available This Gensor Unit is not yet available This Gensor Unit is not yet available This Gensor Unit is not yet available This Gensor Unit is not yet available This Gensor Unit is not yet available gadY gadY_mRNA glnK-amtB glnK-amtB_mRNA hdeAB-yhiD hdeAB-yhiD_mRNA hdeD hdeD_mRNA hns hns_mRNA lon lon_mRNA rpoS rpoS_mRNA slp-dctR slp-dctR_mRNA uspE uspE_mRNA ybaST ybaST_mRNA TonB ExbB ExbD BtuB BtuF BtuC BtuD BtuB ExbD ExbB TonB TolC MdtE MdtF CO2


Gensor Unit       
Name: GadX
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0045848 - positive regulation of nitrogen utilization
GO:0071468 - cellular response to acidic pH
GO:0046930 - pore complex
GO:0015889 - cobalamin transport
GO:0008360 - regulation of cell shape
GO:0006808 - regulation of nitrogen utilization
GO:0008236 - serine-type peptidase activity
GO:0045926 - negative regulation of growth
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0051082 - unfolded protein binding
GO:0016020 - membrane
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Components:
Function Name Type
RNA ybaST_mRNA RNA


Reactions       
Showing 71 reactions
asnB asnB_mRNA
Name: asnB -> asnB_mRNA
Description: Transcription of transcription unit asnB; reaction activation by GadX.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product asnB_mRNA RNA nd nd
reactant asnB gene nd nd
btuB-murI btuB-murI_mRNA
Name: btuB-murI -> btuB-murI_mRNA
Description: Transcription of transcription unit btuB-murI; reaction inhibition by GadX.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant btuB-murI gene nd nd
product btuB-murI_mRNA RNA nd nd
cadBA cadBA_mRNA
Name: cadBA -> cadBA_mRNA
Description: Transcription of transcription unit cadBA; reaction activation by CadC.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product cadBA_mRNA RNA nd nd
reactant cadBA gene nd nd
gadAX gadAX_mRNA
Name: gadAX -> gadAX_mRNA
Description: Transcription of transcription unit gadAX; reaction activation by AdiY.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant gadAX gene nd nd
product gadAX_mRNA RNA nd nd
gadBC gadBC_mRNA
Name: gadBC -> gadBC_mRNA
Description: Transcription of transcription unit gadBC; reaction activation by AdiY.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant gadBC gene nd nd
product gadBC_mRNA RNA nd nd
gadE gadE_mRNA
Name: gadE -> gadE_mRNA
Description: Transcription of transcription unit gadE; reaction activation by GadE.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant gadE gene nd nd
product gadE_mRNA RNA nd nd
gadE-mdtEF gadE-mdtEF_mRNA
Name: gadE-mdtEF -> gadE-mdtEF_mRNA
Description: Transcription of transcription unit gadE-mdtEF; reaction activation by EvgA-Phosphorylated.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant gadE-mdtEF gene nd nd
product gadE-mdtEF_mRNA RNA nd nd
gadW gadW_mRNA
Name: gadW -> gadW_mRNA
Description: Transcription of transcription unit gadW; reaction inhibition by GadW.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant gadW gene nd nd
product gadW_mRNA RNA nd nd
gadX gadX_mRNA
Name: gadX -> gadX_mRNA
Description: Transcription of transcription unit gadX; reaction activation by GadE.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product gadX_mRNA RNA nd nd
reactant gadX gene nd nd
gadXW gadXW_mRNA
Name: gadXW -> gadXW_mRNA
Description: Transcription of transcription unit gadXW; reaction activation by GadE.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product gadXW_mRNA RNA nd nd
reactant gadXW gene nd nd
gadY gadY_mRNA
Name: gadY -> gadY_mRNA
Description: Transcription of transcription unit gadY; reaction inhibition by GadW.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product gadY_mRNA RNA nd nd
reactant gadY gene nd nd
glnK-amtB glnK-amtB_mRNA
Name: glnK-amtB -> glnK-amtB_mRNA
Description: Transcription of transcription unit glnK-amtB; reaction inhibition by Fur-Fe(II).
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant glnK-amtB gene nd nd
product glnK-amtB_mRNA RNA nd nd
hdeAB-yhiD hdeAB-yhiD_mRNA
Name: hdeAB-yhiD -> hdeAB-yhiD_mRNA
Description: Transcription of transcription unit hdeAB-yhiD; reaction inhibition by FliZ.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product hdeAB-yhiD_mRNA RNA nd nd
reactant hdeAB-yhiD gene nd nd
hdeD hdeD_mRNA
Name: hdeD -> hdeD_mRNA
Description: Transcription of transcription unit hdeD; reaction activation by GadE.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant hdeD gene nd nd
product hdeD_mRNA RNA nd nd
hns hns_mRNA
Name: hns -> hns_mRNA
Description: Transcription of transcription unit hns; reaction activation by CspA.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product hns_mRNA RNA nd nd
reactant hns gene nd nd
lon lon_mRNA
Name: lon -> lon_mRNA
Description: Transcription of transcription unit lon; reaction activation by GadX.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant lon gene nd nd
product lon_mRNA RNA nd nd
rpoS rpoS_mRNA
Name: rpoS -> rpoS_mRNA
Description: Transcription of transcription unit rpoS; reaction inhibition by Fur-Fe(II).
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product rpoS_mRNA RNA nd nd
reactant rpoS gene nd nd
slp-dctR slp-dctR_mRNA
Name: slp-dctR -> slp-dctR_mRNA
Description: Transcription of transcription unit slp-dctR; reaction activation by GadE-RcsB.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant slp-dctR gene nd nd
product slp-dctR_mRNA RNA nd nd
uspE uspE_mRNA
Name: uspE -> uspE_mRNA
Description: Transcription of transcription unit uspE; reaction activation by GadX.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product uspE_mRNA RNA nd nd
reactant uspE gene nd nd
ybaST ybaST_mRNA
Name: ybaST -> ybaST_mRNA
Description: Transcription of transcription unit ybaST; reaction activation by GadX.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant ybaST gene nd nd
product ybaST_mRNA RNA nd nd
btuB-murI_mRNA BtuB
Name: btuB-murI_mRNA -> BtuB
Description: Translation of BtuB
Type: translation
Components:
Function Name Type Evidence Reference(s)
product BtuB protein nd nd
reactant btuB-murI_mRNA RNA nd nd
TonB + ExbB + ExbD + BtuB + BtuF + BtuC + BtuD TonB-ExbB-ExbD-BtuB-BtuF-BtuC-BtuD
Name: TonB + ExbB + ExbD + BtuB + BtuF + BtuC + BtuD -> TonB-ExbB-ExbD-BtuB-BtuF-BtuC-BtuD
Description: Reaction transforming TonB, ExbB, ExbD, BtuB, BtuF, BtuC, BtuD into TonB-ExbB-ExbD-BtuB-BtuF-BtuC-BtuD
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant BtuB protein nd nd
reactant BtuC protein nd nd
reactant ExbB protein nd nd
reactant BtuF protein nd nd
product TonB-ExbB-ExbD-BtuB-BtuF-BtuC-BtuD complex nd nd
reactant TonB protein nd nd
reactant BtuD protein nd nd
reactant ExbD protein nd nd
Cbi_Ext Cbi
Name: Cbi_Ext -> Cbi
Description: Transport of Cbi_Ext through a bacterial membrane, leading to the presence of Cbi inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant Cbi_Ext simple molecule nd nd
product Cbi simple molecule nd nd
B12_Ext B12
Name: B12_Ext -> B12
Description: Transport of B12_Ext through a bacterial membrane, leading to the presence of B12 inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product B12 simple molecule nd nd
reactant B12_Ext simple molecule nd nd
BtuB + ExbD + ExbB + TonB BtuB-ExbD-ExbB-TonB
Name: BtuB + ExbD + ExbB + TonB -> BtuB-ExbD-ExbB-TonB
Description: Reaction transforming BtuB, ExbD, ExbB, TonB into BtuB-ExbD-ExbB-TonB
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant TonB protein nd nd
reactant BtuB protein nd nd
reactant ExbD protein nd nd
product BtuB-ExbD-ExbB-TonB complex nd nd
reactant ExbB protein nd nd
slp-dctR_mRNA Slp
Name: slp-dctR_mRNA -> Slp
Description: Translation of Slp
Type: translation
Components:
Function Name Type Evidence Reference(s)
product Slp protein nd nd
reactant slp-dctR_mRNA RNA nd nd
gadE-mdtEF_mRNA GadE
Name: gadE-mdtEF_mRNA -> GadE
Description: Translation of GadE
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadE-mdtEF_mRNA RNA nd nd
product GadE protein nd nd
rpoS_mRNA RpoS
Name: rpoS_mRNA -> RpoS
Description: Translation of RpoS
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant rpoS_mRNA RNA nd nd
product RpoS protein nd nd
rpoS_mRNA RNA polymerase sigma 38
Name: rpoS_mRNA -> RNA polymerase sigma 38
Description: Translation of RNA polymerase sigma 38
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant rpoS_mRNA RNA nd nd
product RNA polymerase sigma 38 RNA nd nd
gadBC_mRNA GadB
Name: gadBC_mRNA -> GadB
Description: Translation of GadB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadBC_mRNA RNA nd nd
product GadB protein nd nd
L-glutamate CO2 + GABA
Name: L-glutamate -> CO2 + GABA
Description: Reaction transforming L-glutamate into CO2, GABA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product CO2 simple molecule nd nd
product GABA simple molecule nd nd
reactant L-glutamate simple molecule nd nd
hdeD_mRNA HdeD
Name: hdeD_mRNA -> HdeD
Description: Translation of HdeD
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant hdeD_mRNA RNA nd nd
product HdeD protein nd nd
cadBA_mRNA CadA
Name: cadBA_mRNA -> CadA
Description: Translation of CadA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product CadA protein nd nd
reactant cadBA_mRNA RNA nd nd
L-lysine CO2 + BioDex 1-
Name: L-lysine -> CO2 + BioDex 1-
Description: Reaction transforming L-lysine into CO2, BioDex 1-
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product CO2 simple molecule nd nd
reactant L-lysine simple molecule nd nd
product BioDex 1- simple molecule nd nd
hns_mRNA Hns
Name: hns_mRNA -> Hns
Description: Translation of Hns
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant hns_mRNA RNA nd nd
product Hns protein nd nd
gadXW_mRNA GadW
Name: gadXW_mRNA -> GadW
Description: Translation of GadW
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadXW_mRNA RNA nd nd
product GadW protein nd nd
btuB-murI_mRNA MurI
Name: btuB-murI_mRNA -> MurI
Description: Translation of MurI
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MurI protein nd nd
reactant btuB-murI_mRNA RNA nd nd
L-glutamate D-glu
Name: L-glutamate -> D-glu
Description: Reaction transforming L-glutamate into D-glu
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product D-glu simple molecule nd nd
reactant L-glutamate simple molecule nd nd
hdeAB-yhiD_mRNA YhiD
Name: hdeAB-yhiD_mRNA -> YhiD
Description: Translation of YhiD
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant hdeAB-yhiD_mRNA RNA nd nd
product YhiD protein nd nd
gadAX_mRNA GadA
Name: gadAX_mRNA -> GadA
Description: Translation of GadA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GadA protein nd nd
reactant gadAX_mRNA RNA nd nd
gadBC_mRNA GadC
Name: gadBC_mRNA -> GadC
Description: Translation of GadC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GadC protein nd nd
reactant gadBC_mRNA RNA nd nd
GABA_Ext + L-glutamate_Ext L-glutamate + GABA
Name: GABA_Ext + L-glutamate_Ext -> L-glutamate + GABA
Description: Transport of GABA_Ext, L-glutamate_Ext through a bacterial membrane, leading to the presence of L-glutamate, GABA inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant GABA_Ext simple molecule nd nd
product GABA simple molecule nd nd
product L-glutamate simple molecule nd nd
reactant L-glutamate_Ext simple molecule nd nd
gadE-mdtEF_mRNA MdtE
Name: gadE-mdtEF_mRNA -> MdtE
Description: Translation of MdtE
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadE-mdtEF_mRNA RNA nd nd
product MdtE protein nd nd
TolC + MdtE + MdtF TolC-MdtE-MdtF
Name: TolC + MdtE + MdtF -> TolC-MdtE-MdtF
Description: Reaction transforming TolC, MdtE, MdtF into TolC-MdtE-MdtF
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product TolC-MdtE-MdtF complex nd nd
reactant MdtF protein nd nd
reactant TolC protein nd nd
reactant MdtE protein nd nd
a drug_Ext a drug
Name: a drug_Ext -> a drug
Description: Transport of a drug_Ext through a bacterial membrane, leading to the presence of a drug inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant a drug_Ext simple molecule nd nd
product a drug simple molecule nd nd
cadBA_mRNA CadB
Name: cadBA_mRNA -> CadB
Description: Translation of CadB
Type: translation
Components:
Function Name Type Evidence Reference(s)
product CadB protein nd nd
reactant cadBA_mRNA RNA nd nd
BioDex 1-_Ext BioDex 1-
Name: BioDex 1-_Ext -> BioDex 1-
Description: Transport of BioDex 1-_Ext through a bacterial membrane, leading to the presence of BioDex 1- inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product BioDex 1- simple molecule nd nd
reactant BioDex 1-_Ext simple molecule nd nd
BioDex 1-_Ext + L-lysine_Ext BioDex 1- + L-lysine
Name: BioDex 1-_Ext + L-lysine_Ext -> BioDex 1- + L-lysine
Description: Transport of BioDex 1-_Ext, L-lysine_Ext through a bacterial membrane, leading to the presence of BioDex 1-, L-lysine inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant BioDex 1-_Ext simple molecule nd nd
product BioDex 1- simple molecule nd nd
product L-lysine simple molecule nd nd
reactant L-lysine_Ext simple molecule nd nd
glnK-amtB_mRNA GlnK
Name: glnK-amtB_mRNA -> GlnK
Description: Translation of GlnK
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant glnK-amtB_mRNA RNA nd nd
product GlnK protein nd nd
slp-dctR_mRNA DctR
Name: slp-dctR_mRNA -> DctR
Description: Translation of DctR
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant slp-dctR_mRNA RNA nd nd
product DctR protein nd nd
gadY_mRNA GadY small regulatory RNA
Name: gadY_mRNA -> GadY small regulatory RNA
Description: Translation of GadY small regulatory RNA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GadY small regulatory RNA RNA nd nd
reactant gadY_mRNA RNA nd nd
ybaST_mRNA YbaT
Name: ybaST_mRNA -> YbaT
Description: Translation of YbaT
Type: translation
Components:
Function Name Type Evidence Reference(s)
product YbaT protein nd nd
reactant ybaST_mRNA RNA nd nd
gadXW_mRNA GadX
Name: gadXW_mRNA -> GadX
Description: Translation of GadX
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GadX protein nd nd
reactant gadXW_mRNA RNA nd nd
gadE-mdtEF_mRNA MdtF
Name: gadE-mdtEF_mRNA -> MdtF
Description: Translation of MdtF
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MdtF protein nd nd
reactant gadE-mdtEF_mRNA RNA nd nd
hdeAB-yhiD_mRNA HdeB
Name: hdeAB-yhiD_mRNA -> HdeB
Description: Translation of HdeB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant hdeAB-yhiD_mRNA RNA nd nd
product HdeB protein nd nd
glnK-amtB_mRNA AmtB
Name: glnK-amtB_mRNA -> AmtB
Description: Translation of AmtB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant glnK-amtB_mRNA RNA nd nd
product AmtB protein nd nd
ammonia_Ext ammonia
Name: ammonia_Ext -> ammonia
Description: Transport of ammonia_Ext through a bacterial membrane, leading to the presence of ammonia inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant ammonia_Ext simple molecule nd nd
product ammonia simple molecule nd nd
ammonium_Ext ammonium
Name: ammonium_Ext -> ammonium
Description: Transport of ammonium_Ext through a bacterial membrane, leading to the presence of ammonium inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant ammonium_Ext simple molecule nd nd
product ammonium simple molecule nd nd
ybaST_mRNA YbaS
Name: ybaST_mRNA -> YbaS
Description: Translation of YbaS
Type: translation
Components:
Function Name Type Evidence Reference(s)
product YbaS protein nd nd
reactant ybaST_mRNA RNA nd nd
L-glutamine L-glutamate + ammonia
Name: L-glutamine -> L-glutamate + ammonia
Description: Reaction transforming L-glutamine into L-glutamate, ammonia
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product L-glutamate simple molecule nd nd
reactant L-glutamine simple molecule nd nd
product ammonia simple molecule nd nd
hdeAB-yhiD_mRNA HdeA
Name: hdeAB-yhiD_mRNA -> HdeA
Description: Translation of HdeA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant hdeAB-yhiD_mRNA RNA nd nd
product HdeA protein nd nd
uspE_mRNA UspE
Name: uspE_mRNA -> UspE
Description: Translation of UspE
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant uspE_mRNA RNA nd nd
product UspE protein nd nd
lon_mRNA Lon
Name: lon_mRNA -> Lon
Description: Translation of Lon
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant lon_mRNA RNA nd nd
product Lon protein nd nd
a protein peptides + peptides
Name: a protein -> peptides + peptides
Description: Reaction transforming a protein into peptides, peptides
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant a protein simple molecule nd nd
product peptides simple molecule nd nd
asnB_mRNA AsnB
Name: asnB_mRNA -> AsnB
Description: Translation of AsnB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant asnB_mRNA RNA nd nd
product AsnB protein nd nd
L-glutamine + asp L-glutamate + L-asparagine + PP
Name: L-glutamine + asp -> L-glutamate + L-asparagine + PP
Description: Reaction transforming L-glutamine, asp into L-glutamate, L-asparagine , PP
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant asp simple molecule nd nd
reactant L-glutamine simple molecule nd nd
product L-asparagine simple molecule nd nd
product PP simple molecule nd nd
product L-glutamate simple molecule nd nd
ammonia + asp L-asparagine + PP
Name: ammonia + asp -> L-asparagine + PP
Description: Reaction transforming ammonia, asp into L-asparagine, PP
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product L-asparagine simple molecule nd nd
product PP simple molecule nd nd
reactant ammonia simple molecule nd nd
reactant asp simple molecule nd nd
gadAX_mRNA GadX
Name: gadAX_mRNA -> GadX
Description: Translation of GadX
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadAX_mRNA RNA nd nd
product GadX protein nd nd
gadW_mRNA GadW
Name: gadW_mRNA -> GadW
Description: Translation of GadW
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GadW protein nd nd
reactant gadW_mRNA RNA nd nd
gadE_mRNA GadE
Name: gadE_mRNA -> GadE
Description: Translation of GadE
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadE_mRNA RNA nd nd
product GadE protein nd nd
gadX_mRNA GadX
Name: gadX_mRNA -> GadX
Description: Translation of GadX
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant gadX_mRNA RNA nd nd
product GadX protein nd nd



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