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GadE-RcsB Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
4-aminobutanoate AdiC AslB CO2 CadA CadB DctR GadA GadE RcsB GadX L-arginine L-arginine_Ext L-glutamate L-lysine L-lysine_Ext Slp YhiM adiC adiC_mRNA agmatine agmatine_Ext aslB aslB_mRNA cadBA cadBA_mRNA cadaverine cadaverine_Ext gadAX gadAX_mRNA slp-dctR slp-dctR_mRNA yhiM yhiM_mRNA GadE RcsB


Gensor Unit       
Name: GadE-RcsB
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:1903401 - L-lysine transmembrane transport
GO:0003333 - amino acid transmembrane transport
GO:0006865 - amino acid transport
GO:1903826 - arginine transmembrane transport
GO:0015839 - cadaverine transport
GO:0006974 - cellular response to DNA damage stimulus
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cellular_component GO:0005829 - cytosol
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0016020 - membrane
GO:0019867 - outer membrane
GO:0005886 - plasma membrane
molecular_function GO:0003700 - DNA binding transcription factor activity
GO:0015171 - amino acid transmembrane transporter activity
GO:0015297 - antiporter activity
GO:0015181 - arginine transmembrane transporter activity
GO:0000986 - bacterial-type proximal promoter sequence-specific DNA binding
GO:0004351 - glutamate decarboxylase activity
GO:0019172 - glyoxalase III activity
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Components: Show/Hide Components Table (33 more...)
Function Name Type
protein AdiC protein
protein AslB protein
simple_molecule BioDex 1- simple_molecule
simple_molecule BioDex 1-_Ext simple_molecule
simple_molecule CO2 simple_molecule
protein CadA protein
protein CadB protein
protein DctR protein
simple_molecule GABA simple_molecule
protein GadA protein
protein GadE-RcsB protein
protein GadX protein
simple_molecule L-glutamate simple_molecule
protein Slp protein
protein YhiM protein
gene adiC gene
RNA adiC_mRNA RNA
simple_molecule agmatine simple_molecule
simple_molecule agmatine_Ext simple_molecule
simple_molecule arginine simple_molecule
simple_molecule arginine_Ext simple_molecule
gene aslB gene
RNA aslB_mRNA RNA
gene cadBA gene
RNA cadBA_mRNA RNA
gene gadAX gene
RNA gadAX_mRNA RNA
simple_molecule lysine simple_molecule
simple_molecule lysine_Ext simple_molecule
gene slp-dctR gene
RNA slp-dctR_mRNA RNA
gene yhiM gene
RNA yhiM_mRNA RNA


Reactions       
Showing 20 reactions
GadE-RcsB adiC adiC_mRNA
Name: adiC -> adiC_mRNA
Description: Transcription of transcription unit adiC. Reaction activation by GadE-RcsB.
Type: transcription
Pathway Components: adiC - GadE-RcsB -> adiC_mRNA
Components:
Function Name Type Evidence Reference(s)
activator GadE-RcsB protein nd nd
reactant adiC gene nd nd
product adiC_mRNA RNA nd nd
GadE-RcsB aslB aslB_mRNA
Name: aslB -> aslB_mRNA
Description: Transcription of transcription unit aslB. Reaction activation by GadE-RcsB.
Type: transcription
Pathway Components: aslB - GadE-RcsB -> aslB_mRNA
Components:
Function Name Type Evidence Reference(s)
activator GadE-RcsB protein nd nd
reactant aslB gene nd nd
product aslB_mRNA RNA nd nd
GadE-RcsB cadBA cadBA_mRNA
Name: cadBA -> cadBA_mRNA
Description: Transcription of transcription unit cadBA. Reaction activation by GadE-RcsB.
Type: transcription
Pathway Components: cadBA - GadE-RcsB -> cadBA_mRNA
Components:
Function Name Type Evidence Reference(s)
activator GadE-RcsB protein nd nd
reactant cadBA gene nd nd
product cadBA_mRNA RNA nd nd
GadE-RcsB gadAX gadAX_mRNA
Name: gadAX -> gadAX_mRNA
Description: Transcription of transcription unit gadAX. Reaction activation by GadE-RcsB.
Type: transcription
Pathway Components: gadAX - GadE-RcsB -> gadAX_mRNA
Components:
Function Name Type Evidence Reference(s)
activator GadE-RcsB protein nd nd
reactant gadAX gene nd nd
product gadAX_mRNA RNA nd nd
GadE-RcsB slp-dctR slp-dctR_mRNA
Name: slp-dctR -> slp-dctR_mRNA
Description: Transcription of transcription unit slp-dctR. Reaction activation by GadE-RcsB.
Type: transcription
Pathway Components: slp-dctR - GadE-RcsB -> slp-dctR_mRNA
Components:
Function Name Type Evidence Reference(s)
activator GadE-RcsB protein nd nd
reactant slp-dctR gene nd nd
product slp-dctR_mRNA RNA nd nd
GadE-RcsB yhiM yhiM_mRNA
Name: yhiM -> yhiM_mRNA
Description: Transcription of transcription unit yhiM. Reaction activation by GadE-RcsB.
Type: transcription
Pathway Components: yhiM - GadE-RcsB -> yhiM_mRNA
Components:
Function Name Type Evidence Reference(s)
activator GadE-RcsB protein nd nd
reactant yhiM gene nd nd
product yhiM_mRNA RNA nd nd
adiC_mRNA AdiC
Name: adiC_mRNA -> AdiC
Description: Translation of AdiC
Type: translation
Pathway Components: adiC_mRNA -> AdiC
Components:
Function Name Type Evidence Reference(s)
product AdiC protein nd nd
reactant adiC_mRNA RNA nd nd
AdiC agmatine_Ext + arginine_Ext agmatine + arginine
Name: agmatine_Ext + arginine_Ext -> agmatine + arginine
Description: Transport of agmatine_Ext, arginine_Ext through a bacterial membrane, leading to the presence of agmatine, arginine inside the cell.
Type: transport
Pathway Components: agmatine_Ext + arginine_Ext - AdiC -> agmatine + arginine
Components:
Function Name Type Evidence Reference(s)
catalyzer AdiC protein nd nd
product agmatine simple_molecule nd nd
reactant agmatine_Ext simple_molecule nd nd
product arginine simple_molecule nd nd
reactant arginine_Ext simple_molecule nd nd
slp-dctR_mRNA Slp
Name: slp-dctR_mRNA -> Slp
Description: Translation of Slp
Type: translation
Pathway Components: slp-dctR_mRNA -> Slp
Components:
Function Name Type Evidence Reference(s)
product Slp protein nd nd
reactant slp-dctR_mRNA RNA nd nd
slp-dctR_mRNA DctR
Name: slp-dctR_mRNA -> DctR
Description: Translation of DctR
Type: translation
Pathway Components: slp-dctR_mRNA -> DctR
Components:
Function Name Type Evidence Reference(s)
product DctR protein nd nd
reactant slp-dctR_mRNA RNA nd nd
gadAX_mRNA GadA
Name: gadAX_mRNA -> GadA
Description: Translation of GadA
Type: translation
Pathway Components: gadAX_mRNA -> GadA
Components:
Function Name Type Evidence Reference(s)
product GadA protein nd nd
reactant gadAX_mRNA RNA nd nd
GadA L-glutamate GABA + CO2
Name: L-glutamate -> GABA + CO2
Description: Reaction transforming L-glutamate into GABA, CO2
Type: state transition
Pathway Components: L-glutamate - GadA -> GABA + CO2
Components:
Function Name Type Evidence Reference(s)
product CO2 simple_molecule nd nd
product GABA simple_molecule nd nd
catalyzer GadA protein nd nd
reactant L-glutamate simple_molecule nd nd
gadAX_mRNA GadX
Name: gadAX_mRNA -> GadX
Description: Translation of GadX
Type: translation
Pathway Components: gadAX_mRNA -> GadX
Components:
Function Name Type Evidence Reference(s)
product GadX protein nd nd
reactant gadAX_mRNA RNA nd nd
yhiM_mRNA YhiM
Name: yhiM_mRNA -> YhiM
Description: Translation of YhiM
Type: translation
Pathway Components: yhiM_mRNA -> YhiM
Components:
Function Name Type Evidence Reference(s)
product YhiM protein nd nd
reactant yhiM_mRNA RNA nd nd
cadBA_mRNA CadB
Name: cadBA_mRNA -> CadB
Description: Translation of CadB
Type: translation
Pathway Components: cadBA_mRNA -> CadB
Components:
Function Name Type Evidence Reference(s)
product CadB protein nd nd
reactant cadBA_mRNA RNA nd nd
CadB agmatine lysine BioDex 1-_Ext BioDex 1-
Name: BioDex 1-_Ext -> BioDex 1-
Description: Transport of BioDex 1-_Ext through a bacterial membrane, leading to the presence of BioDex 1- inside the cell.
Type: transport
Pathway Components: BioDex 1-_Ext - CadB - agmatine - lysine -> BioDex 1-
Components:
Function Name Type Evidence Reference(s)
product BioDex 1- simple_molecule nd nd
reactant BioDex 1-_Ext simple_molecule nd nd
catalyzer CadB protein nd nd
inhibitor agmatine simple_molecule nd nd
inhibitor lysine simple_molecule nd nd
CadB agmatine arginine BioDex 1-_Ext + lysine_Ext BioDex 1- + lysine
Name: BioDex 1-_Ext + lysine_Ext -> BioDex 1- + lysine
Description: Transport of BioDex 1-_Ext, lysine_Ext through a bacterial membrane, leading to the presence of BioDex 1-, lysine inside the cell.
Type: transport
Pathway Components: BioDex 1-_Ext + lysine_Ext - CadB - agmatine - arginine -> BioDex 1- + lysine
Components:
Function Name Type Evidence Reference(s)
product BioDex 1- simple_molecule nd nd
reactant BioDex 1-_Ext simple_molecule nd nd
catalyzer CadB protein nd nd
inhibitor agmatine simple_molecule nd nd
inhibitor arginine simple_molecule nd nd
product lysine simple_molecule nd nd
reactant lysine_Ext simple_molecule nd nd
cadBA_mRNA CadA
Name: cadBA_mRNA -> CadA
Description: Translation of CadA
Type: translation
Pathway Components: cadBA_mRNA -> CadA
Components:
Function Name Type Evidence Reference(s)
product CadA protein nd nd
reactant cadBA_mRNA RNA nd nd
CadA lysine BioDex 1- + CO2
Name: lysine -> BioDex 1- + CO2
Description: Reaction transforming lysine into BioDex 1-, CO2
Type: state transition
Pathway Components: lysine - CadA -> BioDex 1- + CO2
Components:
Function Name Type Evidence Reference(s)
product BioDex 1- simple_molecule nd nd
product CO2 simple_molecule nd nd
catalyzer CadA protein nd nd
reactant lysine simple_molecule nd nd
aslB_mRNA AslB
Name: aslB_mRNA -> AslB
Description: Translation of AslB
Type: translation
Pathway Components: aslB_mRNA -> AslB
Components:
Function Name Type Evidence Reference(s)
product AslB protein nd nd
reactant aslB_mRNA RNA nd nd



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