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FliZ Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
GABA GABA_Ext CO2 CsgA CsgB CsgC CsgD CsgE CsgF CsgG FlhC FlhD FliZ GadB GadC GadE Gmr HdeA HdeB L-glutamate L-glutamate_Ext MdtE MdtF MlrA OsmY TolC YhiD a drug a drug_Ext csgBAC csgBAC_mRNA csgDEFG csgDEFG_mRNA CsgA CsgA_Ext cyclic di-3',5'-guanylate flhDC flhDC_mRNA gadBC gadBC_mRNA gadE-mdtEF gadE-mdtEF_mRNA gmr gmr_mRNA hdeAB-yhiD hdeAB-yhiD_mRNA 5'pGpG mlrA mlrA_mRNA osmY osmY_mRNA CsgG CsgE CsgF TolC MdtE MdtF


Gensor Unit       
Name: FliZ
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:1902475 - L-alpha-amino acid transmembrane transport
GO:0015807 - L-amino acid transport
GO:0003333 - amino acid transmembrane transport
GO:1990000 - amyloid fibril formation
GO:0015721 - bile acid and bile salt transport
GO:0022610 - biological adhesion
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cellular_component GO:0009279 - cell outer membrane
GO:0005829 - cytosol
GO:0005887 - integral component of plasma membrane
GO:0031246 - intrinsic component of periplasmic side of cell outer membrane
GO:0031226 - intrinsic component of plasma membrane
GO:0016020 - membrane
GO:0030288 - outer membrane-bounded periplasmic space
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molecular_function GO:0003677 - DNA binding
GO:0003700 - DNA binding transcription factor activity
GO:0005525 - GTP binding
GO:0015179 - L-amino acid transmembrane transporter activity
GO:0015297 - antiporter activity
GO:0000986 - bacterial-type proximal promoter sequence-specific DNA binding
GO:0051087 - chaperone binding
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Components: Show/Hide Components Table (55 more...)
Function Name Type
simple_molecule 5'pGpG simple_molecule
simple_molecule CO2 simple_molecule
simple_molecule CsgA simple_molecule
simple_molecule CsgA_Ext simple_molecule
protein CsgB protein
protein CsgC protein
protein CsgD protein
protein CsgE protein
complex CsgE-CsgG complex
protein CsgF protein
protein CsgG protein
protein FlhC protein
protein FlhD protein
complex FlhD-FlhC complex
protein FliZ protein
simple_molecule GABA simple_molecule
simple_molecule GABA_Ext simple_molecule
protein GadB protein
protein GadC protein
protein GadE protein
protein HdeA protein
protein HdeB protein
simple_molecule L-glutamate simple_molecule
simple_molecule L-glutamate_Ext simple_molecule
protein MdtE protein
protein MdtF protein
protein MlrA protein
protein OsmY protein
protein PdeR protein
protein RcsB protein
complex RcsB-GadE complex
protein TolC protein
complex TolC-MdtE-MdtF complex
protein YhiD protein
simple_molecule c-di-GMP simple_molecule
gene csgBAC gene
RNA csgBAC_mRNA RNA
gene csgDEFG gene
RNA csgDEFG_mRNA RNA
simple_molecule drug simple_molecule
simple_molecule drug_Ext simple_molecule
gene flhDC gene
RNA flhDC_mRNA RNA
gene gadBC gene
RNA gadBC_mRNA RNA
gene gadE-mdtEF gene
RNA gadE-mdtEF_mRNA RNA
gene hdeAB-yhiD gene
RNA hdeAB-yhiD_mRNA RNA
gene mlrA gene
RNA mlrA_mRNA RNA
gene osmY gene
RNA osmY_mRNA RNA
gene pdeR gene
RNA pdeR_mRNA RNA


Reactions       
Showing 38 reactions
FliZ csgBAC csgBAC_mRNA
Name: csgBAC -> csgBAC_mRNA
Description: Transcription of transcription unit csgBAC. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: csgBAC - FliZ -> csgBAC_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor FliZ protein nd nd
reactant csgBAC gene nd nd
product csgBAC_mRNA RNA nd nd
FliZ csgDEFG csgDEFG_mRNA
Name: csgDEFG -> csgDEFG_mRNA
Description: Transcription of transcription unit csgDEFG. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: csgDEFG - FliZ -> csgDEFG_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor FliZ protein nd nd
reactant csgDEFG gene nd nd
product csgDEFG_mRNA RNA nd nd
FliZ flhDC flhDC_mRNA
Name: flhDC -> flhDC_mRNA
Description: Transcription of transcription unit flhDC. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: flhDC - FliZ -> flhDC_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor FliZ protein nd nd
reactant flhDC gene nd nd
product flhDC_mRNA RNA nd nd
FliZ gadBC gadBC_mRNA
Name: gadBC -> gadBC_mRNA
Description: Transcription of transcription unit gadBC. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: gadBC - FliZ -> gadBC_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor FliZ protein nd nd
reactant gadBC gene nd nd
product gadBC_mRNA RNA nd nd
FliZ gadE-mdtEF gadE-mdtEF_mRNA
Name: gadE-mdtEF -> gadE-mdtEF_mRNA
Description: Transcription of transcription unit gadE-mdtEF. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: gadE-mdtEF - FliZ -> gadE-mdtEF_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor FliZ protein nd nd
reactant gadE-mdtEF gene nd nd
product gadE-mdtEF_mRNA RNA nd nd
FliZ hdeAB-yhiD hdeAB-yhiD_mRNA
Name: hdeAB-yhiD -> hdeAB-yhiD_mRNA
Description: Transcription of transcription unit hdeAB-yhiD. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: hdeAB-yhiD - FliZ -> hdeAB-yhiD_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor FliZ protein nd nd
reactant hdeAB-yhiD gene nd nd
product hdeAB-yhiD_mRNA RNA nd nd
FliZ mlrA mlrA_mRNA
Name: mlrA -> mlrA_mRNA
Description: Transcription of transcription unit mlrA. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: mlrA - FliZ -> mlrA_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor FliZ protein nd nd
reactant mlrA gene nd nd
product mlrA_mRNA RNA nd nd
FliZ osmY osmY_mRNA
Name: osmY -> osmY_mRNA
Description: Transcription of transcription unit osmY. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: osmY - FliZ -> osmY_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor FliZ protein nd nd
reactant osmY gene nd nd
product osmY_mRNA RNA nd nd
FliZ pdeR pdeR_mRNA
Name: pdeR -> pdeR_mRNA
Description: Transcription of transcription unit pdeR. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: pdeR - FliZ -> pdeR_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor FliZ protein nd nd
reactant pdeR gene nd nd
product pdeR_mRNA RNA nd nd
hdeAB-yhiD_mRNA HdeA
Name: hdeAB-yhiD_mRNA -> HdeA
Description: Translation of HdeA
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> HdeA
Components:
Function Name Type Evidence Reference(s)
product HdeA protein nd nd
reactant hdeAB-yhiD_mRNA RNA nd nd
hdeAB-yhiD_mRNA HdeB
Name: hdeAB-yhiD_mRNA -> HdeB
Description: Translation of HdeB
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> HdeB
Components:
Function Name Type Evidence Reference(s)
product HdeB protein nd nd
reactant hdeAB-yhiD_mRNA RNA nd nd
hdeAB-yhiD_mRNA YhiD
Name: hdeAB-yhiD_mRNA -> YhiD
Description: Translation of YhiD
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> YhiD
Components:
Function Name Type Evidence Reference(s)
product YhiD protein nd nd
reactant hdeAB-yhiD_mRNA RNA nd nd
flhDC_mRNA FlhD
Name: flhDC_mRNA -> FlhD
Description: Translation of FlhD
Type: translation
Pathway Components: flhDC_mRNA -> FlhD
Components:
Function Name Type Evidence Reference(s)
product FlhD protein nd nd
reactant flhDC_mRNA RNA nd nd
FlhC + FlhD FlhD-FlhC
Name: FlhC + FlhD -> FlhD-FlhC
Description: Reaction transforming FlhC, FlhD into FlhD-FlhC
Type: state transition
Pathway Components: FlhC + FlhD -> FlhD-FlhC
Components:
Function Name Type Evidence Reference(s)
reactant FlhC protein nd nd
reactant FlhD protein nd nd
product FlhD-FlhC complex nd nd
flhDC_mRNA FlhC
Name: flhDC_mRNA -> FlhC
Description: Translation of FlhC
Type: translation
Pathway Components: flhDC_mRNA -> FlhC
Components:
Function Name Type Evidence Reference(s)
product FlhC protein nd nd
reactant flhDC_mRNA RNA nd nd
gadBC_mRNA GadB
Name: gadBC_mRNA -> GadB
Description: Translation of GadB
Type: translation
Pathway Components: gadBC_mRNA -> GadB
Components:
Function Name Type Evidence Reference(s)
product GadB protein nd nd
reactant gadBC_mRNA RNA nd nd
GadB L-glutamate GABA + CO2
Name: L-glutamate -> GABA + CO2
Description: Reaction transforming L-glutamate into GABA, CO2
Type: state transition
Pathway Components: L-glutamate - GadB -> GABA + CO2
Components:
Function Name Type Evidence Reference(s)
product CO2 simple_molecule nd nd
product GABA simple_molecule nd nd
catalyzer GadB protein nd nd
reactant L-glutamate simple_molecule nd nd
gadBC_mRNA GadC
Name: gadBC_mRNA -> GadC
Description: Translation of GadC
Type: translation
Pathway Components: gadBC_mRNA -> GadC
Components:
Function Name Type Evidence Reference(s)
product GadC protein nd nd
reactant gadBC_mRNA RNA nd nd
GadC L-glutamate_Ext + GABA_Ext L-glutamate + GABA
Name: L-glutamate_Ext + GABA_Ext -> L-glutamate + GABA
Description: Transport of L-glutamate_Ext, GABA_Ext through a bacterial membrane, leading to the presence of L-glutamate, GABA inside the cell.
Type: transport
Pathway Components: L-glutamate_Ext + GABA_Ext - GadC -> L-glutamate + GABA
Components:
Function Name Type Evidence Reference(s)
product GABA simple_molecule nd nd
reactant GABA_Ext simple_molecule nd nd
catalyzer GadC protein nd nd
product L-glutamate simple_molecule nd nd
reactant L-glutamate_Ext simple_molecule nd nd
osmY_mRNA OsmY
Name: osmY_mRNA -> OsmY
Description: Translation of OsmY
Type: translation
Pathway Components: osmY_mRNA -> OsmY
Components:
Function Name Type Evidence Reference(s)
product OsmY protein nd nd
reactant osmY_mRNA RNA nd nd
csgBAC_mRNA CsgB
Name: csgBAC_mRNA -> CsgB
Description: Translation of CsgB
Type: translation
Pathway Components: csgBAC_mRNA -> CsgB
Components:
Function Name Type Evidence Reference(s)
product CsgB protein nd nd
reactant csgBAC_mRNA RNA nd nd
csgBAC_mRNA CsgA
Name: csgBAC_mRNA -> CsgA
Description: Translation of CsgA
Type: translation
Pathway Components: csgBAC_mRNA -> CsgA
Components:
Function Name Type Evidence Reference(s)
product CsgA simple_molecule nd nd
reactant csgBAC_mRNA RNA nd nd
csgBAC_mRNA CsgC
Name: csgBAC_mRNA -> CsgC
Description: Translation of CsgC
Type: translation
Pathway Components: csgBAC_mRNA -> CsgC
Components:
Function Name Type Evidence Reference(s)
product CsgC protein nd nd
reactant csgBAC_mRNA RNA nd nd
mlrA_mRNA MlrA
Name: mlrA_mRNA -> MlrA
Description: Translation of MlrA
Type: translation
Pathway Components: mlrA_mRNA -> MlrA
Components:
Function Name Type Evidence Reference(s)
product MlrA protein nd nd
reactant mlrA_mRNA RNA nd nd
gadE-mdtEF_mRNA GadE
Name: gadE-mdtEF_mRNA -> GadE
Description: Translation of GadE
Type: translation
Pathway Components: gadE-mdtEF_mRNA -> GadE
Components:
Function Name Type Evidence Reference(s)
product GadE protein nd nd
reactant gadE-mdtEF_mRNA RNA nd nd
RcsB + GadE RcsB-GadE
Name: RcsB + GadE -> RcsB-GadE
Description: Reaction transforming RcsB, GadE into RcsB-GadE
Type: state transition
Pathway Components: RcsB + GadE -> RcsB-GadE
Components:
Function Name Type Evidence Reference(s)
reactant GadE protein nd nd
reactant RcsB protein nd nd
product RcsB-GadE complex nd nd
gadE-mdtEF_mRNA MdtE
Name: gadE-mdtEF_mRNA -> MdtE
Description: Translation of MdtE
Type: translation
Pathway Components: gadE-mdtEF_mRNA -> MdtE
Components:
Function Name Type Evidence Reference(s)
product MdtE protein nd nd
reactant gadE-mdtEF_mRNA RNA nd nd
MdtF + MdtE + TolC TolC-MdtE-MdtF
Name: MdtF + MdtE + TolC -> TolC-MdtE-MdtF
Description: Reaction transforming MdtF, MdtE, TolC into TolC-MdtE-MdtF
Type: state transition
Pathway Components: MdtF + MdtE + TolC -> TolC-MdtE-MdtF
Components:
Function Name Type Evidence Reference(s)
reactant MdtE protein nd nd
reactant MdtF protein nd nd
reactant TolC protein nd nd
product TolC-MdtE-MdtF complex nd nd
TolC-MdtE-MdtF drug_Ext drug
Name: drug_Ext -> drug
Description: Transport of drug_Ext through a bacterial membrane, leading to the presence of drug inside the cell.
Type: transport
Pathway Components: drug_Ext - TolC-MdtE-MdtF -> drug
Components:
Function Name Type Evidence Reference(s)
catalyzer TolC-MdtE-MdtF complex nd nd
product drug simple_molecule nd nd
reactant drug_Ext simple_molecule nd nd
gadE-mdtEF_mRNA MdtF
Name: gadE-mdtEF_mRNA -> MdtF
Description: Translation of MdtF
Type: translation
Pathway Components: gadE-mdtEF_mRNA -> MdtF
Components:
Function Name Type Evidence Reference(s)
product MdtF protein nd nd
reactant gadE-mdtEF_mRNA RNA nd nd
csgDEFG_mRNA CsgD
Name: csgDEFG_mRNA -> CsgD
Description: Translation of CsgD
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgD
Components:
Function Name Type Evidence Reference(s)
product CsgD protein nd nd
reactant csgDEFG_mRNA RNA nd nd
csgDEFG_mRNA CsgE
Name: csgDEFG_mRNA -> CsgE
Description: Translation of CsgE
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgE
Components:
Function Name Type Evidence Reference(s)
product CsgE protein nd nd
reactant csgDEFG_mRNA RNA nd nd
CsgG + CsgE CsgE-CsgG
Name: CsgG + CsgE -> CsgE-CsgG
Description: Reaction transforming CsgG, CsgE into CsgE-CsgG
Type: state transition
Pathway Components: CsgG + CsgE -> CsgE-CsgG
Components:
Function Name Type Evidence Reference(s)
reactant CsgE protein nd nd
product CsgE-CsgG complex nd nd
reactant CsgG protein nd nd
CsgE-CsgG CsgA_Ext CsgA
Name: CsgA_Ext -> CsgA
Description: Transport of CsgA_Ext through a bacterial membrane, leading to the presence of CsgA inside the cell.
Type: transport
Pathway Components: CsgA_Ext - CsgE-CsgG -> CsgA
Components:
Function Name Type Evidence Reference(s)
product CsgA simple_molecule nd nd
reactant CsgA_Ext simple_molecule nd nd
catalyzer CsgE-CsgG complex nd nd
csgDEFG_mRNA CsgF
Name: csgDEFG_mRNA -> CsgF
Description: Translation of CsgF
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgF
Components:
Function Name Type Evidence Reference(s)
product CsgF protein nd nd
reactant csgDEFG_mRNA RNA nd nd
csgDEFG_mRNA CsgG
Name: csgDEFG_mRNA -> CsgG
Description: Translation of CsgG
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgG
Components:
Function Name Type Evidence Reference(s)
product CsgG protein nd nd
reactant csgDEFG_mRNA RNA nd nd
pdeR_mRNA PdeR
Name: pdeR_mRNA -> PdeR
Description: Translation of PdeR
Type: translation
Pathway Components: pdeR_mRNA -> PdeR
Components:
Function Name Type Evidence Reference(s)
product PdeR protein nd nd
reactant pdeR_mRNA RNA nd nd
PdeR c-di-GMP 5'pGpG
Name: c-di-GMP -> 5'pGpG
Description: Reaction transforming c-di-GMP into 5'pGpG
Type: state transition
Pathway Components: c-di-GMP - PdeR -> 5'pGpG
Components:
Function Name Type Evidence Reference(s)
product 5'pGpG simple_molecule nd nd
catalyzer PdeR protein nd nd
reactant c-di-GMP simple_molecule nd nd



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