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ExuR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
KDG altronate fructuronate galaturonate galaturonate_Ext GlcA GlcA_Ext mannonate tagaturonate ExuR ExuT UxaA UxaB UxaC UxuA UxuB UxuR exuR exuR_mRNA exuT exuT_mRNA uxaB uxaB_mRNA uxaCA uxaCA_mRNA uxuAB uxuAB_mRNA uxuR uxuR_mRNA


Gensor Unit       
Name: ExuR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:0019698 - D-galacturonate catabolic process
GO:0042840 - D-glucuronate catabolic process
GO:0006820 - anion transport
GO:0006974 - cellular response to DNA damage stimulus
GO:0015736 - hexuronate transmembrane transport
GO:0015778 - hexuronide transport
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cellular_component GO:0005829 - cytosol
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0005886 - plasma membrane
molecular_function GO:0051287 - NAD binding
GO:0008789 - altronate dehydratase activity
GO:0008198 - ferrous iron binding
GO:0008866 - fructuronate reductase activity
GO:0008880 - glucuronate isomerase activity
GO:0015134 - hexuronate transmembrane transporter activity
GO:0030145 - manganese ion binding
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Components: Show/Hide Components Table (31 more...)
Function Name Type
simple_molecule 2-keto-3-deoxygluconate simple_molecule
protein ExuR protein
protein ExuT protein
simple_molecule GlcA simple_molecule
simple_molecule GlcA_Ext simple_molecule
protein UxaA protein
protein UxaB protein
protein UxaC protein
protein UxuA protein
protein UxuB protein
protein UxuR protein
simple_molecule aldehydo-D-galacturonate simple_molecule
simple_molecule aldehydo-D-glucuronate simple_molecule
simple_molecule altronate simple_molecule
gene exuR gene
RNA exuR_mRNA RNA
gene exuT gene
RNA exuT_mRNA RNA
simple_molecule fructuronate simple_molecule
simple_molecule galaturonate simple_molecule
simple_molecule galaturonate_Ext simple_molecule
simple_molecule mannonate simple_molecule
simple_molecule tagaturonate simple_molecule
gene uxaB gene
RNA uxaB_mRNA RNA
gene uxaCA gene
RNA uxaCA_mRNA RNA
gene uxuAB gene
RNA uxuAB_mRNA RNA
gene uxuR gene
RNA uxuR_mRNA RNA


Reactions       
Showing 22 reactions
ExuR exuR exuR_mRNA
Name: exuR -> exuR_mRNA
Description: Transcription of transcription unit exuR. Reaction inhibition by ExuR.
Type: transcription
Pathway Components: exuR - ExuR -> exuR_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor ExuR protein nd nd
reactant exuR gene nd nd
product exuR_mRNA RNA nd nd
ExuR exuT exuT_mRNA
Name: exuT -> exuT_mRNA
Description: Transcription of transcription unit exuT. Reaction inhibition by ExuR.
Type: transcription
Pathway Components: exuT - ExuR -> exuT_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor ExuR protein nd nd
reactant exuT gene nd nd
product exuT_mRNA RNA nd nd
ExuR uxaB uxaB_mRNA
Name: uxaB -> uxaB_mRNA
Description: Transcription of transcription unit uxaB. Reaction inhibition by ExuR.
Type: transcription
Pathway Components: uxaB - ExuR -> uxaB_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor ExuR protein nd nd
reactant uxaB gene nd nd
product uxaB_mRNA RNA nd nd
ExuR uxaCA uxaCA_mRNA
Name: uxaCA -> uxaCA_mRNA
Description: Transcription of transcription unit uxaCA. Reaction inhibition by ExuR.
Type: transcription
Pathway Components: uxaCA - ExuR -> uxaCA_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor ExuR protein nd nd
reactant uxaCA gene nd nd
product uxaCA_mRNA RNA nd nd
ExuR uxuAB uxuAB_mRNA
Name: uxuAB -> uxuAB_mRNA
Description: Transcription of transcription unit uxuAB. Reaction inhibition by ExuR.
Type: transcription
Pathway Components: uxuAB - ExuR -> uxuAB_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor ExuR protein nd nd
reactant uxuAB gene nd nd
product uxuAB_mRNA RNA nd nd
ExuR uxuR uxuR_mRNA
Name: uxuR -> uxuR_mRNA
Description: Transcription of transcription unit uxuR. Reaction inhibition by ExuR.
Type: transcription
Pathway Components: uxuR - ExuR -> uxuR_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor ExuR protein nd nd
reactant uxuR gene nd nd
product uxuR_mRNA RNA nd nd
uxaCA_mRNA UxaC
Name: uxaCA_mRNA -> UxaC
Description: Translation of UxaC
Type: translation
Pathway Components: uxaCA_mRNA -> UxaC
Components:
Function Name Type Evidence Reference(s)
product UxaC protein nd nd
reactant uxaCA_mRNA RNA nd nd
UxaC aldehydo-D-glucuronate fructuronate
Name: aldehydo-D-glucuronate -> fructuronate
Description: Reaction transforming aldehydo-D-glucuronate into fructuronate
Type: state transition
Pathway Components: aldehydo-D-glucuronate - UxaC -> fructuronate
Components:
Function Name Type Evidence Reference(s)
catalyzer UxaC protein nd nd
reactant aldehydo-D-glucuronate simple_molecule nd nd
product fructuronate simple_molecule nd nd
UxaC aldehydo-D-galacturonate tagaturonate
Name: aldehydo-D-galacturonate -> tagaturonate
Description: Reaction transforming aldehydo-D-galacturonate into tagaturonate
Type: state transition
Pathway Components: aldehydo-D-galacturonate - UxaC -> tagaturonate
Components:
Function Name Type Evidence Reference(s)
catalyzer UxaC protein nd nd
reactant aldehydo-D-galacturonate simple_molecule nd nd
product tagaturonate simple_molecule nd nd
uxaCA_mRNA UxaA
Name: uxaCA_mRNA -> UxaA
Description: Translation of UxaA
Type: translation
Pathway Components: uxaCA_mRNA -> UxaA
Components:
Function Name Type Evidence Reference(s)
product UxaA protein nd nd
reactant uxaCA_mRNA RNA nd nd
UxaA altronate 2-keto-3-deoxygluconate
Name: altronate -> 2-keto-3-deoxygluconate
Description: Reaction transforming altronate into 2-keto-3-deoxygluconate
Type: state transition
Pathway Components: altronate - UxaA -> 2-keto-3-deoxygluconate
Components:
Function Name Type Evidence Reference(s)
product 2-keto-3-deoxygluconate simple_molecule nd nd
catalyzer UxaA protein nd nd
reactant altronate simple_molecule nd nd
exuT_mRNA ExuT
Name: exuT_mRNA -> ExuT
Description: Translation of ExuT
Type: translation
Pathway Components: exuT_mRNA -> ExuT
Components:
Function Name Type Evidence Reference(s)
product ExuT protein nd nd
reactant exuT_mRNA RNA nd nd
ExuT galaturonate_Ext galaturonate
Name: galaturonate_Ext -> galaturonate
Description: Transport of galaturonate_Ext through a bacterial membrane, leading to the presence of galaturonate inside the cell.
Type: transport
Pathway Components: galaturonate_Ext - ExuT -> galaturonate
Components:
Function Name Type Evidence Reference(s)
catalyzer ExuT protein nd nd
product galaturonate simple_molecule nd nd
reactant galaturonate_Ext simple_molecule nd nd
ExuT GlcA_Ext GlcA
Name: GlcA_Ext -> GlcA
Description: Transport of GlcA_Ext through a bacterial membrane, leading to the presence of GlcA inside the cell.
Type: transport
Pathway Components: GlcA_Ext - ExuT -> GlcA
Components:
Function Name Type Evidence Reference(s)
catalyzer ExuT protein nd nd
product GlcA simple_molecule nd nd
reactant GlcA_Ext simple_molecule nd nd
exuR_mRNA ExuR
Name: exuR_mRNA -> ExuR
Description: Translation of ExuR
Type: translation
Pathway Components: exuR_mRNA -> ExuR
Components:
Function Name Type Evidence Reference(s)
product ExuR protein nd nd
reactant exuR_mRNA RNA nd nd
uxuAB_mRNA UxuA
Name: uxuAB_mRNA -> UxuA
Description: Translation of UxuA
Type: translation
Pathway Components: uxuAB_mRNA -> UxuA
Components:
Function Name Type Evidence Reference(s)
product UxuA protein nd nd
reactant uxuAB_mRNA RNA nd nd
GlcA UxuA aldehydo-D-galacturonate aldehydo-D-glucuronate altronate galaturonate tagaturonate mannonate 2-keto-3-deoxygluconate
Name: mannonate -> 2-keto-3-deoxygluconate
Description: Reaction transforming mannonate into 2-keto-3-deoxygluconate
Type: state transition
Pathway Components: mannonate - UxuA - GlcA - aldehydo-D-galacturonate - aldehydo-D-glucuronate - altronate - galaturonate - tagaturonate -> 2-keto-3-deoxygluconate
Components: Show/Hide Components Table
uxuAB_mRNA UxuB
Name: uxuAB_mRNA -> UxuB
Description: Translation of UxuB
Type: translation
Pathway Components: uxuAB_mRNA -> UxuB
Components:
Function Name Type Evidence Reference(s)
product UxuB protein nd nd
reactant uxuAB_mRNA RNA nd nd
UxuB mannonate fructuronate
Name: mannonate -> fructuronate
Description: Reaction transforming mannonate into fructuronate
Type: state transition
Pathway Components: mannonate - UxuB -> fructuronate
Components:
Function Name Type Evidence Reference(s)
catalyzer UxuB protein nd nd
product fructuronate simple_molecule nd nd
reactant mannonate simple_molecule nd nd
uxaB_mRNA UxaB
Name: uxaB_mRNA -> UxaB
Description: Translation of UxaB
Type: translation
Pathway Components: uxaB_mRNA -> UxaB
Components:
Function Name Type Evidence Reference(s)
product UxaB protein nd nd
reactant uxaB_mRNA RNA nd nd
UxaB fructuronate mannonate altronate tagaturonate
Name: altronate -> tagaturonate
Description: Reaction transforming altronate into tagaturonate
Type: state transition
Pathway Components: altronate - UxaB - fructuronate - mannonate -> tagaturonate
Components:
Function Name Type Evidence Reference(s)
catalyzer UxaB protein nd nd
reactant altronate simple_molecule nd nd
inhibitor fructuronate simple_molecule nd nd
inhibitor mannonate simple_molecule nd nd
product tagaturonate simple_molecule nd nd
uxuR_mRNA UxuR
Name: uxuR_mRNA -> UxuR
Description: Translation of UxuR
Type: translation
Pathway Components: uxuR_mRNA -> UxuR
Components:
Function Name Type Evidence Reference(s)
product UxuR protein nd nd
reactant uxuR_mRNA RNA nd nd



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