RegulonDB RegulonDB

EnvR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
AcrA AcrB AcrD EnvR TolC a drug a drug_Ext acrAB acrAB_mRNA AcrA TolC AcrB AcrD AcrA TolC


Gensor Unit       
Name: EnvR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0016020 - membrane
GO:0005887 - integral component of plasma membrane
GO:0055085 - transmembrane transport
GO:0046677 - response to antibiotic
GO:0015238 - drug transmembrane transporter activity
GO:0006855 - drug transmembrane transport
GO:0042802 - identical protein binding
GO:0005886 - plasma membrane
GO:0042493 - response to drug
GO:0015721 - bile acid and bile salt transport
GO:0015307 - drug:proton antiporter activity
Read more >
Components:
Function Name Type
RNA acrAB_mRNA RNA


Reactions       
Showing 6 reactions
acrAB acrAB_mRNA
Name: acrAB -> acrAB_mRNA
Description: Transcription of transcription unit acrAB; reaction inhibition by AcrR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant acrAB gene nd nd
product acrAB_mRNA RNA nd nd
acrAB_mRNA AcrA
Name: acrAB_mRNA -> AcrA
Description: Translation of AcrA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant acrAB_mRNA RNA nd nd
product AcrA protein nd nd
AcrA + TolC + AcrB AcrA-TolC-AcrB
Name: AcrA + TolC + AcrB -> AcrA-TolC-AcrB
Description: Reaction transforming AcrA, TolC, AcrB into AcrA-TolC-AcrB
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product AcrA-TolC-AcrB complex nd nd
reactant AcrB protein nd nd
reactant AcrA protein nd nd
reactant TolC protein nd nd
a drug_Ext a drug
Name: a drug_Ext -> a drug
Description: Transport of a drug_Ext through a bacterial membrane, leading to the presence of a drug inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant a drug_Ext simple molecule nd nd
product a drug simple molecule nd nd
AcrD + AcrA + TolC AcrD-AcrA-TolC
Name: AcrD + AcrA + TolC -> AcrD-AcrA-TolC
Description: Reaction transforming AcrD, AcrA, TolC into AcrD-AcrA-TolC
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant AcrA protein nd nd
reactant TolC protein nd nd
reactant AcrD protein nd nd
product AcrD-AcrA-TolC complex nd nd
acrAB_mRNA AcrB
Name: acrAB_mRNA -> AcrB
Description: Translation of AcrB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant acrAB_mRNA RNA nd nd
product AcrB protein nd nd



RegulonDB