RegulonDB RegulonDB

DpiA Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
L-malate 2'-(5-triphosphoribosyl)-3'-dephospho-CoA AppY CitC CitD CitE CitF CitG CitX galaturonate galaturonate_Ext GlcA GlcA_Ext DpiA DpiB ExuT Mdh phosphate a [citrate-lyase] (acetyl form) a [citrate-lyase] (citryl form) a [citrate-lyase] (thiol form) a citrate lyase apo-[acyl-carrier protein] a citrate lyase holo-[acyl-carrier protein] acetate adenine appY appY_mRNA citCDEFXG citCDEFXG_mRNA cit dephospho-CoA PP dpiBA dpiBA_mRNA exuT exuT_mRNA mdh mdh_mRNA oxalacetate DpiA phosphate CitD CitF CitE


Gensor Unit       
Name: DpiA
Signal name: citrate
anaerobiosis.
Classification:
Groups: GUs related to the two-component system
Gene Ontology Terms (GO): biological_process GO:0009061 - anaerobic respiration
GO:0006820 - anion transport
GO:0006464 - cellular protein modification process
GO:0071310 - cellular response to organic substance
GO:0016036 - cellular response to phosphate starvation
GO:0006113 - fermentation
Read more >
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019898 - extrinsic component of membrane
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0005622 - intracellular
GO:0016020 - membrane
Read more >
molecular_function GO:0003677 - DNA binding
GO:0003700 - DNA binding transcription factor activity
GO:0008771 - [citrate (pro-3S)-lyase] ligase activity
GO:0019172 - glyoxalase III activity
GO:0015134 - hexuronate transmembrane transporter activity
GO:0050519 - holo-citrate lyase synthase activity
GO:0000287 - magnesium ion binding
Read more >
Components: Show/Hide Components Table (38 more...)
Function Name Type
simple_molecule 2-5-triphosphoribosyl-3-dephospho-CoA simple_molecule
simple_molecule 3-dephospho-CoA simple_molecule
protein AppY protein
protein CitC protein
protein CitD protein
complex CitD-CitF-CitE complex
protein CitE protein
protein CitF protein
protein CitG protein
protein CitX protein
protein DpiA protein
complex DpiA-phosphate complex
protein DpiB protein
protein ExuT protein
simple_molecule GlcA simple_molecule
simple_molecule GlcA_Ext simple_molecule
protein Mdh protein
simple_molecule [a citrate-lyase acyl-carrier protein] simple_molecule
simple_molecule [a holo citrate lyase acyl-carrier protein] simple_molecule
simple_molecule acetate simple_molecule
simple_molecule adenine simple_molecule
gene appY gene
RNA appY_mRNA RNA
gene citCDEFXG gene
RNA citCDEFXG_mRNA RNA
simple_molecule citrate lyase simple_molecule
simple_molecule diphosphate simple_molecule
gene dpiBA gene
RNA dpiBA_mRNA RNA
gene exuT gene
RNA exuT_mRNA RNA
simple_molecule galaturonate simple_molecule
simple_molecule galaturonate_Ext simple_molecule
simple_molecule malate simple_molecule
gene mdh gene
RNA mdh_mRNA RNA
simple_molecule oxalacetate simple_molecule
simple_molecule phosphate simple_molecule


Reactions       
Showing 24 reactions
phosphate + DpiA DpiA-phosphate
Name: phosphate + DpiA -> DpiA-phosphate
Description: Reaction transforming phosphate, DpiA into DpiA-phosphate
Type: state transition
Pathway Components: phosphate + DpiA -> DpiA-phosphate
Components:
Function Name Type Evidence Reference(s)
reactant DpiA protein nd nd
product DpiA-phosphate complex nd nd
reactant phosphate simple_molecule nd nd
DpiA-phosphate citCDEFXG citCDEFXG_mRNA
Name: citCDEFXG -> citCDEFXG_mRNA
Description: Transcription of transcription unit citCDEFXG. Reaction activation by DpiA-phosphate.
Type: transcription
Pathway Components: citCDEFXG - DpiA-phosphate -> citCDEFXG_mRNA
Components:
Function Name Type Evidence Reference(s)
activator DpiA-phosphate complex nd nd
reactant citCDEFXG gene nd nd
product citCDEFXG_mRNA RNA nd nd
DpiA-phosphate dpiBA dpiBA_mRNA
Name: dpiBA -> dpiBA_mRNA
Description: Transcription of transcription unit dpiBA. Reaction activation by DpiA-phosphate.
Type: transcription
Pathway Components: dpiBA - DpiA-phosphate -> dpiBA_mRNA
Components:
Function Name Type Evidence Reference(s)
activator DpiA-phosphate complex nd nd
reactant dpiBA gene nd nd
product dpiBA_mRNA RNA nd nd
DpiA-phosphate exuT exuT_mRNA
Name: exuT -> exuT_mRNA
Description: Transcription of transcription unit exuT. Reaction activation by DpiA-phosphate.
Type: transcription
Pathway Components: exuT - DpiA-phosphate -> exuT_mRNA
Components:
Function Name Type Evidence Reference(s)
activator DpiA-phosphate complex nd nd
reactant exuT gene nd nd
product exuT_mRNA RNA nd nd
DpiA-phosphate mdh mdh_mRNA
Name: mdh -> mdh_mRNA
Description: Transcription of transcription unit mdh. Reaction activation by DpiA-phosphate.
Type: transcription
Pathway Components: mdh - DpiA-phosphate -> mdh_mRNA
Components:
Function Name Type Evidence Reference(s)
activator DpiA-phosphate complex nd nd
reactant mdh gene nd nd
product mdh_mRNA RNA nd nd
DpiA-phosphate appY appY_mRNA
Name: appY -> appY_mRNA
Description: Transcription of transcription unit appY. Reaction inhibition by DpiA-phosphate.
Type: transcription
Pathway Components: appY - DpiA-phosphate -> appY_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor DpiA-phosphate complex nd nd
reactant appY gene nd nd
product appY_mRNA RNA nd nd
citCDEFXG_mRNA CitC
Name: citCDEFXG_mRNA -> CitC
Description: Translation of CitC
Type: translation
Pathway Components: citCDEFXG_mRNA -> CitC
Components:
Function Name Type Evidence Reference(s)
product CitC protein nd nd
reactant citCDEFXG_mRNA RNA nd nd
CitC Reactants citrate lyase + diphosphate
Name: [a holo citrate lyase acyl-carrier protein] + acetate -> citrate lyase + diphosphate
Description: Reaction transforming [a holo citrate lyase acyl-carrier protein], acetate into citrate lyase, diphosphate
Type: state transition
Pathway Components: [a holo citrate lyase acyl-carrier protein] + acetate - CitC -> citrate lyase + diphosphate
Components:
Function Name Type Evidence Reference(s)
catalyzer CitC protein nd nd
reactant [a holo citrate lyase acyl-carrier protein] simple_molecule nd nd
reactant acetate simple_molecule nd nd
product citrate lyase simple_molecule nd nd
product diphosphate simple_molecule nd nd
citCDEFXG_mRNA CitD
Name: citCDEFXG_mRNA -> CitD
Description: Translation of CitD
Type: translation
Pathway Components: citCDEFXG_mRNA -> CitD
Components:
Function Name Type Evidence Reference(s)
product CitD protein nd nd
reactant citCDEFXG_mRNA RNA nd nd
CitD + CitF + CitE CitD-CitF-CitE
Name: CitD + CitF + CitE -> CitD-CitF-CitE
Description: Reaction transforming CitD, CitF, CitE into CitD-CitF-CitE
Type: state transition
Pathway Components: CitD + CitF + CitE -> CitD-CitF-CitE
Components:
Function Name Type Evidence Reference(s)
reactant CitD protein nd nd
product CitD-CitF-CitE complex nd nd
reactant CitE protein nd nd
reactant CitF protein nd nd
citCDEFXG_mRNA CitE
Name: citCDEFXG_mRNA -> CitE
Description: Translation of CitE
Type: translation
Pathway Components: citCDEFXG_mRNA -> CitE
Components:
Function Name Type Evidence Reference(s)
product CitE protein nd nd
reactant citCDEFXG_mRNA RNA nd nd
citCDEFXG_mRNA CitF
Name: citCDEFXG_mRNA -> CitF
Description: Translation of CitF
Type: translation
Pathway Components: citCDEFXG_mRNA -> CitF
Components:
Function Name Type Evidence Reference(s)
product CitF protein nd nd
reactant citCDEFXG_mRNA RNA nd nd
citCDEFXG_mRNA CitX
Name: citCDEFXG_mRNA -> CitX
Description: Translation of CitX
Type: translation
Pathway Components: citCDEFXG_mRNA -> CitX
Components:
Function Name Type Evidence Reference(s)
product CitX protein nd nd
reactant citCDEFXG_mRNA RNA nd nd
CitX Reactants Products
Name: [a citrate-lyase acyl-carrier protein] + 2-5-triphosphoribosyl-3-dephospho-CoA -> [a holo citrate lyase acyl-carrier protein] + diphosphate
Description: Reaction transforming [a citrate-lyase acyl-carrier protein], 2-5-triphosphoribosyl-3-dephospho-CoA into [a holo citrate lyase acyl-carrier protein], diphosphate
Type: state transition
Pathway Components: [a citrate-lyase acyl-carrier protein] + 2-5-triphosphoribosyl-3-dephospho-CoA - CitX -> [a holo citrate lyase acyl-carrier protein] + diphosphate
Components:
Function Name Type Evidence Reference(s)
reactant 2-5-triphosphoribosyl-3-dephospho-CoA simple_molecule nd nd
catalyzer CitX protein nd nd
reactant [a citrate-lyase acyl-carrier protein] simple_molecule nd nd
product [a holo citrate lyase acyl-carrier protein] simple_molecule nd nd
product diphosphate simple_molecule nd nd
citCDEFXG_mRNA CitG
Name: citCDEFXG_mRNA -> CitG
Description: Translation of CitG
Type: translation
Pathway Components: citCDEFXG_mRNA -> CitG
Components:
Function Name Type Evidence Reference(s)
product CitG protein nd nd
reactant citCDEFXG_mRNA RNA nd nd
CitG 3-dephospho-CoA 2-5-triphosphoribosyl-3-dephospho-CoA + adenine
Name: 3-dephospho-CoA -> 2-5-triphosphoribosyl-3-dephospho-CoA + adenine
Description: Reaction transforming 3-dephospho-CoA into 2-5-triphosphoribosyl-3-dephospho-CoA, adenine
Type: state transition
Pathway Components: 3-dephospho-CoA - CitG -> 2-5-triphosphoribosyl-3-dephospho-CoA + adenine
Components:
Function Name Type Evidence Reference(s)
product 2-5-triphosphoribosyl-3-dephospho-CoA simple_molecule nd nd
reactant 3-dephospho-CoA simple_molecule nd nd
catalyzer CitG protein nd nd
product adenine simple_molecule nd nd
mdh_mRNA Mdh
Name: mdh_mRNA -> Mdh
Description: Translation of Mdh
Type: translation
Pathway Components: mdh_mRNA -> Mdh
Components:
Function Name Type Evidence Reference(s)
product Mdh protein nd nd
reactant mdh_mRNA RNA nd nd
Mdh malate oxalacetate
Name: malate -> oxalacetate
Description: Reaction transforming malate into oxalacetate
Type: state transition
Pathway Components: malate - Mdh -> oxalacetate
Components:
Function Name Type Evidence Reference(s)
catalyzer Mdh protein nd nd
reactant malate simple_molecule nd nd
product oxalacetate simple_molecule nd nd
dpiBA_mRNA DpiB
Name: dpiBA_mRNA -> DpiB
Description: Translation of DpiB
Type: translation
Pathway Components: dpiBA_mRNA -> DpiB
Components:
Function Name Type Evidence Reference(s)
product DpiB protein nd nd
reactant dpiBA_mRNA RNA nd nd
dpiBA_mRNA DpiA
Name: dpiBA_mRNA -> DpiA
Description: Translation of DpiA
Type: translation
Pathway Components: dpiBA_mRNA -> DpiA
Components:
Function Name Type Evidence Reference(s)
product DpiA protein nd nd
reactant dpiBA_mRNA RNA nd nd
appY_mRNA AppY
Name: appY_mRNA -> AppY
Description: Translation of AppY
Type: translation
Pathway Components: appY_mRNA -> AppY
Components:
Function Name Type Evidence Reference(s)
product AppY protein nd nd
reactant appY_mRNA RNA nd nd
exuT_mRNA ExuT
Name: exuT_mRNA -> ExuT
Description: Translation of ExuT
Type: translation
Pathway Components: exuT_mRNA -> ExuT
Components:
Function Name Type Evidence Reference(s)
product ExuT protein nd nd
reactant exuT_mRNA RNA nd nd
ExuT galaturonate_Ext galaturonate
Name: galaturonate_Ext -> galaturonate
Description: Transport of galaturonate_Ext through a bacterial membrane, leading to the presence of galaturonate inside the cell.
Type: transport
Pathway Components: galaturonate_Ext - ExuT -> galaturonate
Components:
Function Name Type Evidence Reference(s)
catalyzer ExuT protein nd nd
product galaturonate simple_molecule nd nd
reactant galaturonate_Ext simple_molecule nd nd
ExuT GlcA_Ext GlcA
Name: GlcA_Ext -> GlcA
Description: Transport of GlcA_Ext through a bacterial membrane, leading to the presence of GlcA inside the cell.
Type: transport
Pathway Components: GlcA_Ext - ExuT -> GlcA
Components:
Function Name Type Evidence Reference(s)
catalyzer ExuT protein nd nd
product GlcA simple_molecule nd nd
reactant GlcA_Ext simple_molecule nd nd



RegulonDB