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DsdC Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
D-serine D-serine_Ext DsdA DsdC DsdX ammonia This Gensor Unit is not yet available This Gensor Unit is not yet available dsdC dsdC_mRNA dsdXA dsdXA_mRNA pyruvate DsdC D-serine


Gensor Unit       
Name: DsdC
Description: DsdC positively regulates the expression of genes involved in serine transportation and catabolism in the presence of serine. The presence of serine induces the expression of genes related to the transport and degradation of serine to pyruvate and ammonium.
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0016020 - membrane
GO:0051410 - detoxification of nitrogen compound
GO:0070178 - D-serine metabolic process
GO:0015128 - gluconate transmembrane transporter activity
GO:0005887 - integral component of plasma membrane
GO:0016829 - lyase activity
GO:0005737 - cytoplasm
GO:0042945 - D-serine transmembrane transporter activity
GO:0003677 - DNA binding
GO:0046416 - D-amino acid metabolic process
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Components:
Function Name Type
simple molecule pyruvate simple molecule


Reactions       
Showing 10 reactions
DsdC + D-serine DsdC-D-serine
Name: DsdC + D-serine -> DsdC-D-serine
Description: Reaction transforming DsdC, D-serine into DsdC-D-serine
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant DsdC protein nd nd
product DsdC-D-serine complex nd nd
reactant D-serine simple molecule nd nd
dsdA dsdA_mRNA
Name: dsdA -> dsdA_mRNA
Description: Transcription of transcription unit dsdA; reaction activation by DsdC-D-serine.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product dsdA_mRNA RNA nd nd
reactant dsdA gene nd nd
dsdC dsdC_mRNA
Name: dsdC -> dsdC_mRNA
Description: Transcription of transcription unit dsdC; reaction inhibition by DsdC-D-serine.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant dsdC gene nd nd
product dsdC_mRNA RNA nd nd
dsdXA dsdXA_mRNA
Name: dsdXA -> dsdXA_mRNA
Description: Transcription of transcription unit dsdXA; reaction activation by DsdC-D-serine.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant dsdXA gene nd nd
product dsdXA_mRNA RNA nd nd
dsdC_mRNA DsdC
Name: dsdC_mRNA -> DsdC
Description: Translation of DsdC
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant dsdC_mRNA RNA nd nd
product DsdC protein nd nd
dsdXA_mRNA DsdA
Name: dsdXA_mRNA -> DsdA
Description: Translation of DsdA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product DsdA protein nd nd
reactant dsdXA_mRNA RNA nd nd
D-serine pyruvate + ammonia
Name: D-serine -> pyruvate + ammonia
Description: Reaction transforming D-serine into pyruvate, ammonia
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product ammonia simple molecule nd nd
reactant D-serine simple molecule nd nd
product pyruvate simple molecule nd nd
dsdXA_mRNA DsdX
Name: dsdXA_mRNA -> DsdX
Description: Translation of DsdX
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant dsdXA_mRNA RNA nd nd
product DsdX protein nd nd
D-serine_Ext D-serine
Name: D-serine_Ext -> D-serine
Description: Transport of D-serine_Ext through a bacterial membrane, leading to the presence of D-serine inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant D-serine_Ext simple molecule nd nd
product D-serine simple molecule nd nd
dsdA_mRNA DsdA
Name: dsdA_mRNA -> DsdA
Description: Translation of DsdA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product DsdA protein nd nd
reactant dsdA_mRNA RNA nd nd



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