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DhaR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
DhaK DhaL DhaM DhaR dhaKLM dhaKLM_mRNA dhaR dhaR_mRNA dihydroxyacetone DHAP PEP pyruvate DhaR DhaK DhaM DhaK DhaL


Gensor Unit       
Name: DhaR
Description: DhaR positively regulates the expression of genes involved in glycerol catabolic processes in the absence of DhaK. The presence DhaK inhibits the expression of genes related to conversion of dihydroxyacetone to dihidroxyacetona phosphate (DHAP), a reaction that is part of the glycerol degradation pathway.
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0019563 - glycerol catabolic process
GO:0009401 - phosphoenolpyruvate-dependent sugar phosphotransferase system
GO:0042182 - ketone catabolic process
GO:0047324 - phosphoenolpyruvate-glycerone phosphotransferase activity
GO:0004871 - signal transducer activity
GO:0016310 - phosphorylation
GO:0005737 - cytoplasm
GO:0008965 - phosphoenolpyruvate-protein phosphotransferase activity
GO:0046365 - monosaccharide catabolic process
GO:0006071 - glycerol metabolic process
GO:0005829 - cytosol
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Components:
Function Name Type
simple molecule pyruvate simple molecule


Reactions       
Showing 9 reactions
dhaKLM dhaKLM_mRNA
Name: dhaKLM -> dhaKLM_mRNA
Description: Transcription of transcription unit dhaKLM; reaction activation by DhaR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product dhaKLM_mRNA RNA nd nd
reactant dhaKLM gene nd nd
dhaR dhaR_mRNA
Name: dhaR -> dhaR_mRNA
Description: Transcription of transcription unit dhaR; reaction inhibition by DhaR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant dhaR gene nd nd
product dhaR_mRNA RNA nd nd
DhaR + DhaK DhaR-DhaK
Name: DhaR + DhaK -> DhaR-DhaK
Description: Reaction transforming DhaR, DhaK into DhaR-DhaK
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant DhaR protein nd nd
reactant DhaK protein nd nd
product DhaR-DhaK complex nd nd
dhaKLM_mRNA DhaM
Name: dhaKLM_mRNA -> DhaM
Description: Translation of DhaM
Type: translation
Components:
Function Name Type Evidence Reference(s)
product DhaM protein nd nd
reactant dhaKLM_mRNA RNA nd nd
DhaM + DhaK + DhaL DhaM-DhaK-DhaL
Name: DhaM + DhaK + DhaL -> DhaM-DhaK-DhaL
Description: Reaction transforming DhaM, DhaK, DhaL into DhaM-DhaK-DhaL
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant DhaM protein nd nd
product DhaM-DhaK-DhaL complex nd nd
reactant DhaL protein nd nd
reactant DhaK protein nd nd
dihydroxyacetone + phosphoenolpyruvate dihydroxyacetone phosphate + pyruvate
Name: dihydroxyacetone + phosphoenolpyruvate -> dihydroxyacetone phosphate + pyruvate
Description: Reaction transforming dihydroxyacetone, phosphoenolpyruvate into dihydroxyacetone phosphate, pyruvate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant dihydroxyacetone simple molecule nd nd
reactant phosphoenolpyruvate simple molecule nd nd
product pyruvate simple molecule nd nd
product dihydroxyacetone phosphate simple molecule nd nd
dhaKLM_mRNA DhaL
Name: dhaKLM_mRNA -> DhaL
Description: Translation of DhaL
Type: translation
Components:
Function Name Type Evidence Reference(s)
product DhaL protein nd nd
reactant dhaKLM_mRNA RNA nd nd
dhaR_mRNA DhaR
Name: dhaR_mRNA -> DhaR
Description: Translation of DhaR
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant dhaR_mRNA RNA nd nd
product DhaR protein nd nd
dhaKLM_mRNA DhaK
Name: dhaKLM_mRNA -> DhaK
Description: Translation of DhaK
Type: translation
Components:
Function Name Type Evidence Reference(s)
product DhaK protein nd nd
reactant dhaKLM_mRNA RNA nd nd



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