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CusR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
silver silver_Ext Cu(I) Cu(I)_Ext CusA CusB CusC CusF CusR CusS phosphate cusCFBA cusCFBA_mRNA cusRS cusRS_mRNA CusR phosphate CusC CusB CusF CusA


Gensor Unit       
Name: CusR
Classification:
Groups: GUs related to the two-component system
Gene Ontology Terms (GO): GO:0046930 - pore complex
GO:0005375 - copper ion transmembrane transporter activity
GO:0016020 - membrane
GO:0060003 - copper ion export
GO:0015080 - silver ion transmembrane transporter activity
GO:0010043 - response to zinc ion
GO:0004871 - signal transducer activity
GO:0006825 - copper ion transport
GO:0016310 - phosphorylation
GO:0042597 - periplasmic space
GO:0006811 - ion transport
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Components:
Function Name Type
RNA cusRS_mRNA RNA


Reactions       
Showing 12 reactions
CusR + phosphate CusR-Pasp
Name: CusR + phosphate -> CusR-Pasp
Description: Reaction transforming CusR, phosphate into CusR-Pasp
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant phosphate simple molecule nd nd
product CusR-Pasp complex nd nd
reactant CusR protein nd nd
cusCFBA cusCFBA_mRNA
Name: cusCFBA -> cusCFBA_mRNA
Description: Transcription of transcription unit cusCFBA; reaction activation by CusR-Pasp.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant cusCFBA gene nd nd
product cusCFBA_mRNA RNA nd nd
cusRS cusRS_mRNA
Name: cusRS -> cusRS_mRNA
Description: Transcription of transcription unit cusRS; reaction activation by CusR-Pasp.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product cusRS_mRNA RNA nd nd
reactant cusRS gene nd nd
cusRS_mRNA CusR
Name: cusRS_mRNA -> CusR
Description: Translation of CusR
Type: translation
Components:
Function Name Type Evidence Reference(s)
product CusR protein nd nd
reactant cusRS_mRNA RNA nd nd
cusCFBA_mRNA CusB
Name: cusCFBA_mRNA -> CusB
Description: Translation of CusB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant cusCFBA_mRNA RNA nd nd
product CusB protein nd nd
CusC + CusB + CusF + CusA CusC-CusB-CusF-CusA
Name: CusC + CusB + CusF + CusA -> CusC-CusB-CusF-CusA
Description: Reaction transforming CusC, CusB, CusF, CusA into CusC-CusB-CusF-CusA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant CusA protein nd nd
reactant CusF protein nd nd
reactant CusB protein nd nd
product CusC-CusB-CusF-CusA complex nd nd
reactant CusC protein nd nd
Cu(I)_Ext Cu(I)
Name: Cu(I)_Ext -> Cu(I)
Description: Transport of Cu(I)_Ext through a bacterial membrane, leading to the presence of Cu(I) inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant Cu(I)_Ext simple molecule nd nd
product Cu(I) simple molecule nd nd
silver_Ext silver
Name: silver_Ext -> silver
Description: Transport of silver_Ext through a bacterial membrane, leading to the presence of silver inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product silver simple molecule nd nd
reactant silver_Ext simple molecule nd nd
cusCFBA_mRNA CusA
Name: cusCFBA_mRNA -> CusA
Description: Translation of CusA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant cusCFBA_mRNA RNA nd nd
product CusA protein nd nd
cusCFBA_mRNA CusF
Name: cusCFBA_mRNA -> CusF
Description: Translation of CusF
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant cusCFBA_mRNA RNA nd nd
product CusF protein nd nd
cusRS_mRNA CusS
Name: cusRS_mRNA -> CusS
Description: Translation of CusS
Type: translation
Components:
Function Name Type Evidence Reference(s)
product CusS protein nd nd
reactant cusRS_mRNA RNA nd nd
cusCFBA_mRNA CusC
Name: cusCFBA_mRNA -> CusC
Description: Translation of CusC
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant cusCFBA_mRNA RNA nd nd
product CusC protein nd nd



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