RegulonDB RegulonDB

CusR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
CusF silver CusR ubiquinone CyoC Cu(I)_Ext CyoE cusCFBA oxygen_Ext YedX (S)-OHCU CusA CyoB CusF CusS cusRS_mRNA ubiquinol_Ext silver_Ext phosphate CyoD diphosphate cyoABCDE CusC Cu(I) yedX_mRNA CusA CusB CusB farnesyl-PP CyoB CyoA cusCFBA_mRNA phosphate (S)-5-hydroxyisourate cusRS cyoABCDE_mRNA yedX CyoC CusC CyoD protoheme IX CusR ferroheme o CyoA


Gensor Unit       
Name: CusR
Signal name: increased copper concentration
Ag.
Classification:
Groups: Inorganic ion transport and metabolism
Energy production and conversion
Signal transduction mechanisms
Coenzyme transport and metabolism
Cell wall/membrane/envelope biogenesis
Nucleotide transport and metabolism
Gene Ontology Terms (GO): biological_process GO:0042773 - ATP synthesis coupled electron transport
GO:0019646 - aerobic electron transport chain
GO:0009060 - aerobic respiration
GO:0006812 - cation transport
GO:0006878 - cellular copper ion homeostasis
GO:0045333 - cellular respiration
Read more >
cellular_component GO:0009279 - cell outer membrane
GO:0009319 - cytochrome o ubiquinol oxidase complex
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0071575 - integral component of external side of plasma membrane
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
Read more >
molecular_function GO:0005524 - ATP binding
GO:0003677 - DNA binding
GO:0008324 - cation transmembrane transporter activity
GO:0016531 - copper chaperone activity
GO:0005507 - copper ion binding
GO:0005375 - copper ion transmembrane transporter activity
GO:0009486 - cytochrome bo3 ubiquinol oxidase activity
Read more >
Components:
  Function Name Type
  simple_molecule (S)-5-hydroxyisourate simple_molecule
  simple_molecule (S)-OHCU simple_molecule
  simple_molecule Cu(I) simple_molecule
  simple_molecule Cu(I)_Ext simple_molecule
  protein CusA protein
  protein CusB protein
  protein CusC protein
  complex CusC-CusB-CusF-CusA complex
  protein CusF protein
  protein CusR protein
  complex CusR-phosphate complex
  protein CusS protein
  protein CyoA protein
  protein CyoB protein
  protein CyoC protein
  protein CyoD protein
  complex CyoD-CyoA-CyoB-CyoC complex
  protein CyoE protein
  protein YedX protein
  gene cusCFBA gene
  RNA cusCFBA_mRNA RNA
  gene cusRS gene
  RNA cusRS_mRNA RNA
  gene cyoABCDE gene
  RNA cyoABCDE_mRNA RNA
  simple_molecule diphosphate simple_molecule
  simple_molecule farnesyl-PP simple_molecule
  simple_molecule ferroheme o simple_molecule
  simple_molecule oxygen_Ext simple_molecule
  simple_molecule phosphate simple_molecule
  simple_molecule protoheme IX simple_molecule
  simple_molecule silver simple_molecule
  simple_molecule silver_Ext simple_molecule
  simple_molecule ubiquinol_Ext simple_molecule
  simple_molecule ubiquinone simple_molecule
  gene yedX gene
  RNA yedX_mRNA RNA


Reactions       
Showing 24 reactions
phosphate + CusR CusR-phosphate
Name: phosphate + CusR -> CusR-phosphate
Description: Reaction transforming phosphate, CusR into CusR-phosphate
Type: state transition
Pathway Components: phosphate + CusR -> CusR-phosphate
Components:
Function Name Type
reactant CusR protein
product CusR-phosphate complex
reactant phosphate simple_molecule
CusR-phosphate cusCFBA cusCFBA_mRNA
Name: cusCFBA -> cusCFBA_mRNA
Description: Transcription of transcription unit cusCFBA. Reaction activation by CusR-phosphate.
Type: transcription
Pathway Components: cusCFBA - CusR-phosphate -> cusCFBA_mRNA
Components:
Function Name Type
activator CusR-phosphate complex
reactant cusCFBA gene
product cusCFBA_mRNA RNA
CusR-phosphate cusRS cusRS_mRNA
Name: cusRS -> cusRS_mRNA
Description: Transcription of transcription unit cusRS. Reaction activation by CusR-phosphate.
Type: transcription
Pathway Components: cusRS - CusR-phosphate -> cusRS_mRNA
Components:
Function Name Type
activator CusR-phosphate complex
reactant cusRS gene
product cusRS_mRNA RNA
CusR-phosphate cyoABCDE cyoABCDE_mRNA
Name: cyoABCDE -> cyoABCDE_mRNA
Description: Transcription of transcription unit cyoABCDE. Reaction activation by CusR-phosphate.
Type: transcription
Pathway Components: cyoABCDE - CusR-phosphate -> cyoABCDE_mRNA
Components:
Function Name Type
activator CusR-phosphate complex
reactant cyoABCDE gene
product cyoABCDE_mRNA RNA
CusR-phosphate yedX yedX_mRNA
Name: yedX -> yedX_mRNA
Description: Transcription of transcription unit yedX. Reaction activation by CusR-phosphate.
Type: transcription
Pathway Components: yedX - CusR-phosphate -> yedX_mRNA
Components:
Function Name Type
activator CusR-phosphate complex
reactant yedX gene
product yedX_mRNA RNA
cyoABCDE_mRNA CyoA
Name: cyoABCDE_mRNA -> CyoA
Description: Translation of CyoA
Type: translation
Pathway Components: cyoABCDE_mRNA -> CyoA
Components:
Function Name Type
product CyoA protein
reactant cyoABCDE_mRNA RNA
CyoA + CyoC + CyoB + CyoD CyoD-CyoA-CyoB-CyoC
Name: CyoA + CyoC + CyoB + CyoD -> CyoD-CyoA-CyoB-CyoC
Description: Reaction transforming CyoA, CyoC, CyoB, CyoD into CyoD-CyoA-CyoB-CyoC
Type: state transition
Pathway Components: CyoA + CyoC + CyoB + CyoD -> CyoD-CyoA-CyoB-CyoC
Components:
Function Name Type
reactant CyoA protein
reactant CyoB protein
reactant CyoC protein
reactant CyoD protein
product CyoD-CyoA-CyoB-CyoC complex
CyoD-CyoA-CyoB-CyoC ubiquinol_Ext + oxygen_Ext ubiquinone
Name: ubiquinol_Ext + oxygen_Ext -> ubiquinone
Description: Transport of ubiquinol_Ext, oxygen_Ext through a bacterial membrane, leading to the presence of ubiquinone inside the cell.
Type: transport
Pathway Components: ubiquinol_Ext + oxygen_Ext - CyoD-CyoA-CyoB-CyoC -> ubiquinone
Components:
Function Name Type
catalyzer CyoD-CyoA-CyoB-CyoC complex
reactant oxygen_Ext simple_molecule
reactant ubiquinol_Ext simple_molecule
product ubiquinone simple_molecule
cyoABCDE_mRNA CyoB
Name: cyoABCDE_mRNA -> CyoB
Description: Translation of CyoB
Type: translation
Pathway Components: cyoABCDE_mRNA -> CyoB
Components:
Function Name Type
product CyoB protein
reactant cyoABCDE_mRNA RNA
cyoABCDE_mRNA CyoC
Name: cyoABCDE_mRNA -> CyoC
Description: Translation of CyoC
Type: translation
Pathway Components: cyoABCDE_mRNA -> CyoC
Components:
Function Name Type
product CyoC protein
reactant cyoABCDE_mRNA RNA
cyoABCDE_mRNA CyoD
Name: cyoABCDE_mRNA -> CyoD
Description: Translation of CyoD
Type: translation
Pathway Components: cyoABCDE_mRNA -> CyoD
Components:
Function Name Type
product CyoD protein
reactant cyoABCDE_mRNA RNA
cyoABCDE_mRNA CyoE
Name: cyoABCDE_mRNA -> CyoE
Description: Translation of CyoE
Type: translation
Pathway Components: cyoABCDE_mRNA -> CyoE
Components:
Function Name Type
product CyoE protein
reactant cyoABCDE_mRNA RNA
CyoE protoheme IX + farnesyl-PP ferroheme o + diphosphate
Name: protoheme IX + farnesyl-PP -> ferroheme o + diphosphate
Description: Reaction transforming protoheme IX, farnesyl-PP into ferroheme o, diphosphate
Type: state transition
Pathway Components: protoheme IX + farnesyl-PP - CyoE -> ferroheme o + diphosphate
Components:
Function Name Type
catalyzer CyoE protein
product diphosphate simple_molecule
reactant farnesyl-PP simple_molecule
product ferroheme o simple_molecule
reactant protoheme IX simple_molecule
cusRS_mRNA CusR
Name: cusRS_mRNA -> CusR
Description: Translation of CusR
Type: translation
Pathway Components: cusRS_mRNA -> CusR
Components:
Function Name Type
product CusR protein
reactant cusRS_mRNA RNA
cusRS_mRNA CusS
Name: cusRS_mRNA -> CusS
Description: Translation of CusS
Type: translation
Pathway Components: cusRS_mRNA -> CusS
Components:
Function Name Type
product CusS protein
reactant cusRS_mRNA RNA
cusCFBA_mRNA CusC
Name: cusCFBA_mRNA -> CusC
Description: Translation of CusC
Type: translation
Pathway Components: cusCFBA_mRNA -> CusC
Components:
Function Name Type
product CusC protein
reactant cusCFBA_mRNA RNA
CusB + CusF + CusC + CusA CusC-CusB-CusF-CusA
Name: CusB + CusF + CusC + CusA -> CusC-CusB-CusF-CusA
Description: Reaction transforming CusB, CusF, CusC, CusA into CusC-CusB-CusF-CusA
Type: state transition
Pathway Components: CusB + CusF + CusC + CusA -> CusC-CusB-CusF-CusA
Components:
Function Name Type
reactant CusA protein
reactant CusB protein
reactant CusC protein
product CusC-CusB-CusF-CusA complex
reactant CusF protein
CusC-CusB-CusF-CusA Cu(I)_Ext Cu(I)
Name: Cu(I)_Ext -> Cu(I)
Description: Transport of Cu(I)_Ext through a bacterial membrane, leading to the presence of Cu(I) inside the cell.
Type: transport
Pathway Components: Cu(I)_Ext - CusC-CusB-CusF-CusA -> Cu(I)
Components:
Function Name Type
product Cu(I) simple_molecule
reactant Cu(I)_Ext simple_molecule
catalyzer CusC-CusB-CusF-CusA complex
CusC-CusB-CusF-CusA silver_Ext silver
Name: silver_Ext -> silver
Description: Transport of silver_Ext through a bacterial membrane, leading to the presence of silver inside the cell.
Type: transport
Pathway Components: silver_Ext - CusC-CusB-CusF-CusA -> silver
Components:
Function Name Type
catalyzer CusC-CusB-CusF-CusA complex
product silver simple_molecule
reactant silver_Ext simple_molecule
cusCFBA_mRNA CusF
Name: cusCFBA_mRNA -> CusF
Description: Translation of CusF
Type: translation
Pathway Components: cusCFBA_mRNA -> CusF
Components:
Function Name Type
product CusF protein
reactant cusCFBA_mRNA RNA
cusCFBA_mRNA CusB
Name: cusCFBA_mRNA -> CusB
Description: Translation of CusB
Type: translation
Pathway Components: cusCFBA_mRNA -> CusB
Components:
Function Name Type
product CusB protein
reactant cusCFBA_mRNA RNA
cusCFBA_mRNA CusA
Name: cusCFBA_mRNA -> CusA
Description: Translation of CusA
Type: translation
Pathway Components: cusCFBA_mRNA -> CusA
Components:
Function Name Type
product CusA protein
reactant cusCFBA_mRNA RNA
yedX_mRNA YedX
Name: yedX_mRNA -> YedX
Description: Translation of YedX
Type: translation
Pathway Components: yedX_mRNA -> YedX
Components:
Function Name Type
product YedX protein
reactant yedX_mRNA RNA
YedX (S)-5-hydroxyisourate (S)-OHCU
Name: (S)-5-hydroxyisourate -> (S)-OHCU
Description: Reaction transforming (S)-5-hydroxyisourate into (S)-OHCU
Type: state transition
Pathway Components: (S)-5-hydroxyisourate - YedX -> (S)-OHCU
Components:
Function Name Type
reactant (S)-5-hydroxyisourate simple_molecule
product (S)-OHCU simple_molecule
catalyzer YedX protein



RegulonDB