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CueR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
2,3-dihydroxybenzoate 2-carboxymuconate CopA Cu(I) Cu(I)_Ext Cu(II) CueO CueR Fe(II) Fe(III) GTP MoaA MoaB MoaC MoaD MoaE small subunit of molybdopterin synthase thiocarboxylated small subunit of molybdopterin synthase copA copA_mRNA cueO cueO_mRNA cyclic pyranopterin phosphate moaABCDE moaABCDE_mRNA molybdopterin CueR Cu(I) MoaD MoaE


Gensor Unit       
Name: CueR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0043682 - copper-transporting ATPase activity
GO:0016491 - oxidoreductase activity
GO:0016020 - membrane
GO:0003824 - catalytic activity
GO:0005525 - GTP binding
GO:0006825 - copper ion transport
GO:0042597 - periplasmic space
GO:0016887 - ATPase activity
GO:0016829 - lyase activity
GO:0006811 - ion transport
GO:0031224 - intrinsic component of membrane
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Components:
Function Name Type
simple molecule molybdopterin simple molecule


Reactions       
Showing 18 reactions
CueR + Cu+ CueR-Cu+
Name: CueR + Cu+ -> CueR-Cu+
Description: Reaction transforming CueR, Cu+ into CueR-Cu+
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant Cu+ simple molecule nd nd
reactant CueR protein nd nd
product CueR-Cu+ complex nd nd
copA copA_mRNA
Name: copA -> copA_mRNA
Description: Transcription of transcription unit copA; reaction activation by CueR-Cu+.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant copA gene nd nd
product copA_mRNA RNA nd nd
cueO cueO_mRNA
Name: cueO -> cueO_mRNA
Description: Transcription of transcription unit cueO; reaction activation by CueR-Cu+.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product cueO_mRNA RNA nd nd
reactant cueO gene nd nd
moaABCDE moaABCDE_mRNA
Name: moaABCDE -> moaABCDE_mRNA
Description: Transcription of transcription unit moaABCDE; reaction inhibition by CueR-Cu+.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant moaABCDE gene nd nd
product moaABCDE_mRNA RNA nd nd
moaABCDE_mRNA MoaC
Name: moaABCDE_mRNA -> MoaC
Description: Translation of MoaC
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant moaABCDE_mRNA RNA nd nd
product MoaC protein nd nd
moaABCDE_mRNA MoaE
Name: moaABCDE_mRNA -> MoaE
Description: Translation of MoaE
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MoaE protein nd nd
reactant moaABCDE_mRNA RNA nd nd
MoaD + MoaE MoaD-MoaE
Name: MoaD + MoaE -> MoaD-MoaE
Description: Reaction transforming MoaD, MoaE into MoaD-MoaE
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant MoaE protein nd nd
reactant MoaD protein nd nd
product MoaD-MoaE complex nd nd
cyclic pyranopterin monophosphate + a thiocarboxylated small subunit of molybdopterin synthase molybdopterin + a small subunit of molybdopterin synthase
Name: cyclic pyranopterin monophosphate + a thiocarboxylated small subunit of molybdopterin synthase -> molybdopterin + a small subunit of molybdopterin synthase
Description: Reaction transforming cyclic pyranopterin monophosphate, a thiocarboxylated small subunit of molybdopterin synthase into molybdopterin, a small subunit of molybdopterin synthase
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product molybdopterin simple molecule nd nd
product a small subunit of molybdopterin synthase simple molecule nd nd
reactant cyclic pyranopterin monophosphate simple molecule nd nd
reactant a thiocarboxylated small subunit of molybdopterin synthase simple molecule nd nd
moaABCDE_mRNA MoaB
Name: moaABCDE_mRNA -> MoaB
Description: Translation of MoaB
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MoaB protein nd nd
reactant moaABCDE_mRNA RNA nd nd
copA_mRNA CopA
Name: copA_mRNA -> CopA
Description: Translation of CopA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant copA_mRNA RNA nd nd
product CopA protein nd nd
Cu+ Cu+_Ext
Name: Cu+ -> Cu+_Ext
Description: Transport of Cu+ through a bacterial membrane, leading to the presence of Cu+_Ext inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product Cu+_Ext simple molecule nd nd
reactant Cu+ simple molecule nd nd
moaABCDE_mRNA MoaA
Name: moaABCDE_mRNA -> MoaA
Description: Translation of MoaA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MoaA protein nd nd
reactant moaABCDE_mRNA RNA nd nd
GTP cyclic pyranopterin monophosphate
Name: GTP -> cyclic pyranopterin monophosphate
Description: Reaction transforming GTP into cyclic pyranopterin monophosphate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant GTP simple molecule nd nd
product cyclic pyranopterin monophosphate simple molecule nd nd
moaABCDE_mRNA MoaD
Name: moaABCDE_mRNA -> MoaD
Description: Translation of MoaD
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant moaABCDE_mRNA RNA nd nd
product MoaD protein nd nd
cueO_mRNA CueO
Name: cueO_mRNA -> CueO
Description: Translation of CueO
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant cueO_mRNA RNA nd nd
product CueO protein nd nd
Cu+ Cu2+
Name: Cu+ -> Cu2+
Description: Reaction transforming Cu+ into Cu2+
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product Cu2+ simple molecule nd nd
reactant Cu+ simple molecule nd nd
2,3-dihydroxybenzoate 2-carboxymuconate
Name: 2,3-dihydroxybenzoate -> 2-carboxymuconate
Description: Reaction transforming 2,3-dihydroxybenzoate into 2-carboxymuconate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant 2,3-dihydroxybenzoate simple molecule nd nd
product 2-carboxymuconate simple molecule nd nd
Fe2+ Fe(III)
Name: Fe2+ -> Fe(III)
Description: Reaction transforming Fe2+ into Fe(III)
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant Fe2+ simple molecule nd nd
product Fe(III) simple molecule nd nd



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