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CreB Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
CreB CreD erythrose-4P D-fructose 6-phosphate D-glyceraldehyde 3-phosphate sedoheptulose-7-P MalE MalF MalG MalK TalA beta-maltose beta-maltose_Ext This Gensor Unit is not yet available This Gensor Unit is not yet available malEFG malEFG_mRNA maltotetraose maltotetraose_Ext maltotriose maltotriose_Ext phosphate talA talA_mRNA CreB phosphate MalK MalF MalG MalE phosphate


Gensor Unit       
Name: CreB
Signal name: lactoferricin B.
Classification:
Groups: GUs related to the two-component system
Gene Ontology Terms (GO): biological_process GO:0008643 - carbohydrate transport
GO:0060326 - cell chemotaxis
GO:0006974 - cellular response to DNA damage stimulus
GO:0034289 - detection of maltose stimulus
GO:0042956 - maltodextrin transport
GO:0015768 - maltose transport
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cellular_component GO:0043190 - ATP-binding cassette (ABC) transporter complex
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
GO:0005829 - cytosol
GO:0005887 - integral component of plasma membrane
GO:1990060 - maltose transport complex
GO:0016020 - membrane
GO:0030288 - outer membrane-bounded periplasmic space
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molecular_function GO:1901982 - maltose binding
GO:0005363 - maltose transmembrane transporter activity
GO:0015423 - maltose-transporting ATPase activity
GO:0005515 - protein binding
GO:0004801 - sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity
GO:0005215 - transporter activity
Components: Show/Hide Components Table (36 more...)
Function Name Type
protein CreA protein
protein CreB protein
complex CreB-phosphate complex
protein CreC protein
protein CreD protein
protein MalE protein
protein MalF protein
protein MalG protein
protein MalK protein
complex MalK-MalF-MalG-MalE complex
protein TalA protein
protein TktB protein
protein YjjE protein
gene creABCD gene
RNA creABCD_mRNA RNA
gene creD gene
RNA creD_mRNA RNA
simple_molecule erythrose-4P simple_molecule
simple_molecule fructose-6-P simple_molecule
simple_molecule glyceraldehyde-P simple_molecule
gene malEFG gene
RNA malEFG_mRNA RNA
simple_molecule maltose simple_molecule
simple_molecule maltose_Ext simple_molecule
simple_molecule maltotetraose simple_molecule
simple_molecule maltotetraose_Ext simple_molecule
simple_molecule maltotriose simple_molecule
simple_molecule maltotriose_Ext simple_molecule
simple_molecule phosphate simple_molecule
simple_molecule ribose-5P simple_molecule
simple_molecule sedoheptulose-7-P simple_molecule
gene talA gene
gene talA-tktB gene
RNA talA-tktB_mRNA RNA
RNA talA_mRNA RNA
simple_molecule xylulose-P simple_molecule


Reactions       
Showing 25 reactions
phosphate + CreB CreB-phosphate
Name: phosphate + CreB -> CreB-phosphate
Description: Reaction transforming phosphate, CreB into CreB-phosphate
Type: state transition
Pathway Components: phosphate + CreB -> CreB-phosphate
Components:
Function Name Type Evidence Reference(s)
reactant CreB protein nd nd
product CreB-phosphate complex nd nd
reactant phosphate simple_molecule nd nd
CreB-phosphate creABCD creABCD_mRNA
Name: creABCD -> creABCD_mRNA
Description: Transcription of transcription unit creABCD. Reaction activation by CreB-phosphate.
Type: transcription
Pathway Components: creABCD - CreB-phosphate -> creABCD_mRNA
Components:
Function Name Type Evidence Reference(s)
activator CreB-phosphate complex nd nd
reactant creABCD gene nd nd
product creABCD_mRNA RNA nd nd
CreB-phosphate talA-tktB talA-tktB_mRNA
Name: talA-tktB -> talA-tktB_mRNA
Description: Transcription of transcription unit talA-tktB. Reaction activation by CreB-phosphate.
Type: transcription
Pathway Components: talA-tktB - CreB-phosphate -> talA-tktB_mRNA
Components:
Function Name Type Evidence Reference(s)
activator CreB-phosphate complex nd nd
reactant talA-tktB gene nd nd
product talA-tktB_mRNA RNA nd nd
CreB-phosphate malEFG malEFG_mRNA
Name: malEFG -> malEFG_mRNA
Description: Transcription of transcription unit malEFG. Reaction inhibition by CreB-phosphate.
Type: transcription
Pathway Components: malEFG - CreB-phosphate -> malEFG_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor CreB-phosphate complex nd nd
reactant malEFG gene nd nd
product malEFG_mRNA RNA nd nd
CreB creD creD_mRNA
Name: creD -> creD_mRNA
Description: Transcription of transcription unit creD. Reaction activation by CreB.
Type: transcription
Pathway Components: creD - CreB -> creD_mRNA
Components:
Function Name Type Evidence Reference(s)
activator CreB protein nd nd
reactant creD gene nd nd
product creD_mRNA RNA nd nd
CreB talA talA_mRNA
Name: talA -> talA_mRNA
Description: Transcription of transcription unit talA. Reaction activation by CreB.
Type: transcription
Pathway Components: talA - CreB -> talA_mRNA
Components:
Function Name Type Evidence Reference(s)
activator CreB protein nd nd
reactant talA gene nd nd
product talA_mRNA RNA nd nd
malEFG_mRNA MalE
Name: malEFG_mRNA -> MalE
Description: Translation of MalE
Type: translation
Pathway Components: malEFG_mRNA -> MalE
Components:
Function Name Type Evidence Reference(s)
product MalE protein nd nd
reactant malEFG_mRNA RNA nd nd
MalE + MalF + MalG + MalK MalK-MalF-MalG-MalE
Name: MalE + MalF + MalG + MalK -> MalK-MalF-MalG-MalE
Description: Reaction transforming MalE, MalF, MalG, MalK into MalK-MalF-MalG-MalE
Type: state transition
Pathway Components: MalE + MalF + MalG + MalK -> MalK-MalF-MalG-MalE
Components:
Function Name Type Evidence Reference(s)
reactant MalE protein nd nd
reactant MalF protein nd nd
reactant MalG protein nd nd
reactant MalK protein nd nd
product MalK-MalF-MalG-MalE complex nd nd
MalK-MalF-MalG-MalE maltose_Ext maltose
Name: maltose_Ext -> maltose
Description: Transport of maltose_Ext through a bacterial membrane, leading to the presence of maltose inside the cell.
Type: transport
Pathway Components: maltose_Ext - MalK-MalF-MalG-MalE -> maltose
Components:
Function Name Type Evidence Reference(s)
catalyzer MalK-MalF-MalG-MalE complex nd nd
product maltose simple_molecule nd nd
reactant maltose_Ext simple_molecule nd nd
MalK-MalF-MalG-MalE maltotetraose_Ext maltotetraose
Name: maltotetraose_Ext -> maltotetraose
Description: Transport of maltotetraose_Ext through a bacterial membrane, leading to the presence of maltotetraose inside the cell.
Type: transport
Pathway Components: maltotetraose_Ext - MalK-MalF-MalG-MalE -> maltotetraose
Components:
Function Name Type Evidence Reference(s)
catalyzer MalK-MalF-MalG-MalE complex nd nd
product maltotetraose simple_molecule nd nd
reactant maltotetraose_Ext simple_molecule nd nd
MalK-MalF-MalG-MalE maltotriose_Ext maltotriose
Name: maltotriose_Ext -> maltotriose
Description: Transport of maltotriose_Ext through a bacterial membrane, leading to the presence of maltotriose inside the cell.
Type: transport
Pathway Components: maltotriose_Ext - MalK-MalF-MalG-MalE -> maltotriose
Components:
Function Name Type Evidence Reference(s)
catalyzer MalK-MalF-MalG-MalE complex nd nd
product maltotriose simple_molecule nd nd
reactant maltotriose_Ext simple_molecule nd nd
malEFG_mRNA MalF
Name: malEFG_mRNA -> MalF
Description: Translation of MalF
Type: translation
Pathway Components: malEFG_mRNA -> MalF
Components:
Function Name Type Evidence Reference(s)
product MalF protein nd nd
reactant malEFG_mRNA RNA nd nd
malEFG_mRNA MalG
Name: malEFG_mRNA -> MalG
Description: Translation of MalG
Type: translation
Pathway Components: malEFG_mRNA -> MalG
Components:
Function Name Type Evidence Reference(s)
product MalG protein nd nd
reactant malEFG_mRNA RNA nd nd
creABCD_mRNA CreA
Name: creABCD_mRNA -> CreA
Description: Translation of CreA
Type: translation
Pathway Components: creABCD_mRNA -> CreA
Components:
Function Name Type Evidence Reference(s)
product CreA protein nd nd
reactant creABCD_mRNA RNA nd nd
creABCD_mRNA CreB
Name: creABCD_mRNA -> CreB
Description: Translation of CreB
Type: translation
Pathway Components: creABCD_mRNA -> CreB
Components:
Function Name Type Evidence Reference(s)
product CreB protein nd nd
reactant creABCD_mRNA RNA nd nd
creABCD_mRNA YjjE
Name: creABCD_mRNA -> YjjE
Description: Translation of YjjE
Type: translation
Pathway Components: creABCD_mRNA -> YjjE
Components:
Function Name Type Evidence Reference(s)
product YjjE protein nd nd
reactant creABCD_mRNA RNA nd nd
creABCD_mRNA CreC
Name: creABCD_mRNA -> CreC
Description: Translation of CreC
Type: translation
Pathway Components: creABCD_mRNA -> CreC
Components:
Function Name Type Evidence Reference(s)
product CreC protein nd nd
reactant creABCD_mRNA RNA nd nd
creABCD_mRNA CreD
Name: creABCD_mRNA -> CreD
Description: Translation of CreD
Type: translation
Pathway Components: creABCD_mRNA -> CreD
Components:
Function Name Type Evidence Reference(s)
product CreD protein nd nd
reactant creABCD_mRNA RNA nd nd
talA-tktB_mRNA TalA
Name: talA-tktB_mRNA -> TalA
Description: Translation of TalA
Type: translation
Pathway Components: talA-tktB_mRNA -> TalA
Components:
Function Name Type Evidence Reference(s)
product TalA protein nd nd
reactant talA-tktB_mRNA RNA nd nd
TalA sedoheptulose-7-P + glyceraldehyde-P erythrose-4P + fructose-6-P
Name: sedoheptulose-7-P + glyceraldehyde-P -> erythrose-4P + fructose-6-P
Description: Reaction transforming sedoheptulose-7-P, glyceraldehyde-P into erythrose-4P, fructose-6-P
Type: state transition
Pathway Components: sedoheptulose-7-P + glyceraldehyde-P - TalA -> erythrose-4P + fructose-6-P
Components:
Function Name Type Evidence Reference(s)
catalyzer TalA protein nd nd
product erythrose-4P simple_molecule nd nd
product fructose-6-P simple_molecule nd nd
reactant glyceraldehyde-P simple_molecule nd nd
reactant sedoheptulose-7-P simple_molecule nd nd
talA-tktB_mRNA TktB
Name: talA-tktB_mRNA -> TktB
Description: Translation of TktB
Type: translation
Pathway Components: talA-tktB_mRNA -> TktB
Components:
Function Name Type Evidence Reference(s)
product TktB protein nd nd
reactant talA-tktB_mRNA RNA nd nd
TktB sedoheptulose-7-P + glyceraldehyde-P xylulose-P + ribose-5P
Name: sedoheptulose-7-P + glyceraldehyde-P -> xylulose-P + ribose-5P
Description: Reaction transforming sedoheptulose-7-P, glyceraldehyde-P into xylulose-P, ribose-5P
Type: state transition
Pathway Components: sedoheptulose-7-P + glyceraldehyde-P - TktB -> xylulose-P + ribose-5P
Components:
Function Name Type Evidence Reference(s)
catalyzer TktB protein nd nd
reactant glyceraldehyde-P simple_molecule nd nd
product ribose-5P simple_molecule nd nd
reactant sedoheptulose-7-P simple_molecule nd nd
product xylulose-P simple_molecule nd nd
TktB erythrose-4P + xylulose-P glyceraldehyde-P + fructose-6-P
Name: erythrose-4P + xylulose-P -> glyceraldehyde-P + fructose-6-P
Description: Reaction transforming erythrose-4P, xylulose-P into glyceraldehyde-P, fructose-6-P
Type: state transition
Pathway Components: erythrose-4P + xylulose-P - TktB -> glyceraldehyde-P + fructose-6-P
Components:
Function Name Type Evidence Reference(s)
catalyzer TktB protein nd nd
reactant erythrose-4P simple_molecule nd nd
product fructose-6-P simple_molecule nd nd
product glyceraldehyde-P simple_molecule nd nd
reactant xylulose-P simple_molecule nd nd
creD_mRNA CreD
Name: creD_mRNA -> CreD
Description: Translation of CreD
Type: translation
Pathway Components: creD_mRNA -> CreD
Components:
Function Name Type Evidence Reference(s)
product CreD protein nd nd
reactant creD_mRNA RNA nd nd
talA_mRNA TalA
Name: talA_mRNA -> TalA
Description: Translation of TalA
Type: translation
Pathway Components: talA_mRNA -> TalA
Components:
Function Name Type Evidence Reference(s)
product TalA protein nd nd
reactant talA_mRNA RNA nd nd



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