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CsiR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
L-2-hydroxyglutarate ketoglutarate GABA GABA_Ext CsiD CsiR GabD GabP GabT L-glutamate LhgO csiD-lhgO-gabDTP csiD-lhgO-gabDTP_mRNA perhydrol oxygen succinate succ-S-ald


Gensor Unit       
Name: CsiR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0003824 - catalytic activity
GO:0016020 - membrane
GO:0016491 - oxidoreductase activity
GO:0005737 - cytoplasm
GO:0004777 - succinate-semialdehyde dehydrogenase (NAD+) activity
GO:0055085 - transmembrane transport
GO:0003333 - amino acid transmembrane transport
GO:0015185 - gamma-aminobutyric acid transmembrane transporter activity
GO:0003867 - 4-aminobutyrate transaminase activity
GO:0030170 - pyridoxal phosphate binding
GO:0052853 - long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity
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Components:
Function Name Type
simple molecule succ-S-ald simple molecule


Reactions       
Showing 10 reactions
csiD-lhgO-gabDTP csiD-lhgO-gabDTP_mRNA
Name: csiD-lhgO-gabDTP -> csiD-lhgO-gabDTP_mRNA
Description: Transcription of transcription unit csiD-lhgO-gabDTP; reaction inhibition by CsiR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant csiD-lhgO-gabDTP gene nd nd
product csiD-lhgO-gabDTP_mRNA RNA nd nd
csiD-lhgO-gabDTP_mRNA LhgO
Name: csiD-lhgO-gabDTP_mRNA -> LhgO
Description: Translation of LhgO
Type: translation
Components:
Function Name Type Evidence Reference(s)
product LhgO protein nd nd
reactant csiD-lhgO-gabDTP_mRNA RNA nd nd
L-2-hydroxyglutarate + oxygen ketoglutarate + perhydrol
Name: L-2-hydroxyglutarate + oxygen -> ketoglutarate + perhydrol
Description: Reaction transforming L-2-hydroxyglutarate, oxygen into ketoglutarate, perhydrol
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant oxygen simple molecule nd nd
product ketoglutarate simple molecule nd nd
reactant L-2-hydroxyglutarate simple molecule nd nd
product perhydrol simple molecule nd nd
csiD-lhgO-gabDTP_mRNA GabT
Name: csiD-lhgO-gabDTP_mRNA -> GabT
Description: Translation of GabT
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GabT protein nd nd
reactant csiD-lhgO-gabDTP_mRNA RNA nd nd
ketoglutarate + GABA L-glutamate + succ-S-ald
Name: ketoglutarate + GABA -> L-glutamate + succ-S-ald
Description: Reaction transforming ketoglutarate, GABA into L-glutamate, succ-S-ald
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product L-glutamate simple molecule nd nd
reactant ketoglutarate simple molecule nd nd
product succ-S-ald simple molecule nd nd
reactant GABA simple molecule nd nd
csiD-lhgO-gabDTP_mRNA CsiD
Name: csiD-lhgO-gabDTP_mRNA -> CsiD
Description: Translation of CsiD
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant csiD-lhgO-gabDTP_mRNA RNA nd nd
product CsiD protein nd nd
csiD-lhgO-gabDTP_mRNA GabD
Name: csiD-lhgO-gabDTP_mRNA -> GabD
Description: Translation of GabD
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant csiD-lhgO-gabDTP_mRNA RNA nd nd
product GabD protein nd nd
succ-S-ald suc
Name: succ-S-ald -> suc
Description: Reaction transforming succ-S-ald into suc
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant succ-S-ald simple molecule nd nd
product suc simple molecule nd nd
csiD-lhgO-gabDTP_mRNA GabP
Name: csiD-lhgO-gabDTP_mRNA -> GabP
Description: Translation of GabP
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GabP protein nd nd
reactant csiD-lhgO-gabDTP_mRNA RNA nd nd
GABA_Ext GABA
Name: GABA_Ext -> GABA
Description: Transport of GABA_Ext through a bacterial membrane, leading to the presence of GABA inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
reactant GABA_Ext simple molecule nd nd
product GABA simple molecule nd nd



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