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Cbl Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
butanesulfonate ketoglutarate Adenosine 5' phosphosulphate CO2 Cbl FMN Reduced FMN SsuA SsuB SsuC SsuD SsuE TauA TauB TauC TauD Thiosulphate aminoacetaldehyde RCHO an aliphatic sulfonate an aliphatic sulfonate_Ext alkanesulfonate butanal glycoaldehyde isethionate oxygen phosphate ssuEADCB ssuEADCB_mRNA succinate sulfite tauABCD tauABCD_mRNA taufon taufon_Ext Cbl Adenosine 5' phosphosulphate Cbl Thiosulphate SsuA SsuC SsuB TauA TauC TauB oxygen sulfite sulfite Reduced FMN oxygen oxygen FMN


Gensor Unit       
Name: Cbl
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:0099133 - ATP hydrolysis coupled anion transmembrane transport
GO:0046306 - alkanesulfonate catabolic process
GO:0042918 - alkanesulfonate transport
GO:0006974 - cellular response to DNA damage stimulus
GO:0009970 - cellular response to sulfate starvation
GO:0010438 - cellular response to sulfur starvation
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cellular_component GO:0043190 - ATP-binding cassette (ABC) transporter complex
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
GO:0005737 - cytoplasm
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0016020 - membrane
GO:0030288 - outer membrane-bounded periplasmic space
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molecular_function GO:0005524 - ATP binding
GO:0008752 - FMN reductase activity
GO:0008726 - alkanesulfonate monooxygenase activity
GO:0042959 - alkanesulfonate transmembrane transporter activity
GO:0042802 - identical protein binding
GO:0005515 - protein binding
GO:0000907 - sulfonate dioxygenase activity
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Components: Show/Hide Components Table (40 more...)
Function Name Type
simple_molecule 3-morpholinopropanal simple_molecule
simple_molecule CO2 simple_molecule
protein Cbl protein
complex Cbl-PAPS complex
complex Cbl-thiosulfate complex
simple_molecule MOPS simple_molecule
simple_molecule PAPS simple_molecule
simple_molecule RCHO simple_molecule
simple_molecule Reduced FMN simple_molecule
protein SsuA protein
complex SsuA-SsuC-SsuB complex
protein SsuB protein
protein SsuC protein
protein SsuD protein
protein SsuE protein
protein TauA protein
complex TauA-TauC-TauB complex
protein TauB protein
protein TauC protein
protein TauD protein
simple_molecule aliphatic sulfonate simple_molecule
simple_molecule aliphatic sulfonate_Ext simple_molecule
simple_molecule alkanesulfonate simple_molecule
simple_molecule aminoacetaldehyde simple_molecule
simple_molecule butanal simple_molecule
simple_molecule butanesulfonate simple_molecule
simple_molecule flavin mononucleotide simple_molecule
simple_molecule glycoaldehyde simple_molecule
simple_molecule isethionate simple_molecule
simple_molecule ketoglutarate simple_molecule
simple_molecule oxygen simple_molecule
gene ssuEADCB gene
RNA ssuEADCB_mRNA RNA
simple_molecule succinate simple_molecule
simple_molecule sulfite simple_molecule
gene tauABCD gene
RNA tauABCD_mRNA RNA
simple_molecule taufon simple_molecule
simple_molecule taufon_Ext simple_molecule
simple_molecule thiosulfate simple_molecule


Reactions       
Showing 23 reactions
Cbl ssuEADCB ssuEADCB_mRNA
Name: ssuEADCB -> ssuEADCB_mRNA
Description: Transcription of transcription unit ssuEADCB. Reaction activation by Cbl.
Type: transcription
Pathway Components: ssuEADCB - Cbl -> ssuEADCB_mRNA
Components:
Function Name Type Evidence Reference(s)
activator Cbl protein nd nd
reactant ssuEADCB gene nd nd
product ssuEADCB_mRNA RNA nd nd
Cbl tauABCD tauABCD_mRNA
Name: tauABCD -> tauABCD_mRNA
Description: Transcription of transcription unit tauABCD. Reaction activation by Cbl.
Type: transcription
Pathway Components: tauABCD - Cbl -> tauABCD_mRNA
Components:
Function Name Type Evidence Reference(s)
activator Cbl protein nd nd
reactant tauABCD gene nd nd
product tauABCD_mRNA RNA nd nd
thiosulfate + Cbl Cbl-thiosulfate
Name: thiosulfate + Cbl -> Cbl-thiosulfate
Description: Reaction transforming thiosulfate, Cbl into Cbl-thiosulfate
Type: state transition
Pathway Components: thiosulfate + Cbl -> Cbl-thiosulfate
Components:
Function Name Type Evidence Reference(s)
reactant Cbl protein nd nd
product Cbl-thiosulfate complex nd nd
reactant thiosulfate simple_molecule nd nd
PAPS + Cbl Cbl-PAPS
Name: PAPS + Cbl -> Cbl-PAPS
Description: Reaction transforming PAPS, Cbl into Cbl-PAPS
Type: state transition
Pathway Components: PAPS + Cbl -> Cbl-PAPS
Components:
Function Name Type Evidence Reference(s)
reactant Cbl protein nd nd
product Cbl-PAPS complex nd nd
reactant PAPS simple_molecule nd nd
tauABCD_mRNA TauA
Name: tauABCD_mRNA -> TauA
Description: Translation of TauA
Type: translation
Pathway Components: tauABCD_mRNA -> TauA
Components:
Function Name Type Evidence Reference(s)
product TauA protein nd nd
reactant tauABCD_mRNA RNA nd nd
TauC + TauA + TauB TauA-TauC-TauB
Name: TauC + TauA + TauB -> TauA-TauC-TauB
Description: Reaction transforming TauC, TauA, TauB into TauA-TauC-TauB
Type: state transition
Pathway Components: TauC + TauA + TauB -> TauA-TauC-TauB
Components:
Function Name Type Evidence Reference(s)
reactant TauA protein nd nd
product TauA-TauC-TauB complex nd nd
reactant TauB protein nd nd
reactant TauC protein nd nd
TauA-TauC-TauB taufon_Ext taufon
Name: taufon_Ext -> taufon
Description: Transport of taufon_Ext through a bacterial membrane, leading to the presence of taufon inside the cell.
Type: transport
Pathway Components: taufon_Ext - TauA-TauC-TauB -> taufon
Components:
Function Name Type Evidence Reference(s)
catalyzer TauA-TauC-TauB complex nd nd
product taufon simple_molecule nd nd
reactant taufon_Ext simple_molecule nd nd
tauABCD_mRNA TauB
Name: tauABCD_mRNA -> TauB
Description: Translation of TauB
Type: translation
Pathway Components: tauABCD_mRNA -> TauB
Components:
Function Name Type Evidence Reference(s)
product TauB protein nd nd
reactant tauABCD_mRNA RNA nd nd
tauABCD_mRNA TauC
Name: tauABCD_mRNA -> TauC
Description: Translation of TauC
Type: translation
Pathway Components: tauABCD_mRNA -> TauC
Components:
Function Name Type Evidence Reference(s)
product TauC protein nd nd
reactant tauABCD_mRNA RNA nd nd
tauABCD_mRNA TauD
Name: tauABCD_mRNA -> TauD
Description: Translation of TauD
Type: translation
Pathway Components: tauABCD_mRNA -> TauD
Components:
Function Name Type Evidence Reference(s)
product TauD protein nd nd
reactant tauABCD_mRNA RNA nd nd
TauD ketoglutarate + taufon + oxygen aminoacetaldehyde + succinate + sulfite + CO2
Name: ketoglutarate + taufon + oxygen -> aminoacetaldehyde + succinate + sulfite + CO2
Description: Reaction transforming ketoglutarate, taufon, oxygen into aminoacetaldehyde, succinate , sulfite , CO2
Type: state transition
Pathway Components: ketoglutarate + taufon + oxygen - TauD -> aminoacetaldehyde + succinate + sulfite + CO2
Components:
Function Name Type Evidence Reference(s)
product CO2 simple_molecule nd nd
catalyzer TauD protein nd nd
product aminoacetaldehyde simple_molecule nd nd
reactant ketoglutarate simple_molecule nd nd
reactant oxygen simple_molecule nd nd
product succinate simple_molecule nd nd
product sulfite simple_molecule nd nd
reactant taufon simple_molecule nd nd
ssuEADCB_mRNA SsuE
Name: ssuEADCB_mRNA -> SsuE
Description: Translation of SsuE
Type: translation
Pathway Components: ssuEADCB_mRNA -> SsuE
Components:
Function Name Type Evidence Reference(s)
product SsuE protein nd nd
reactant ssuEADCB_mRNA RNA nd nd
SsuE flavin mononucleotide Reduced FMN
Name: flavin mononucleotide -> Reduced FMN
Description: Reaction transforming flavin mononucleotide into Reduced FMN
Type: state transition
Pathway Components: flavin mononucleotide - SsuE -> Reduced FMN
Components:
Function Name Type Evidence Reference(s)
product Reduced FMN simple_molecule nd nd
catalyzer SsuE protein nd nd
reactant flavin mononucleotide simple_molecule nd nd
ssuEADCB_mRNA SsuA
Name: ssuEADCB_mRNA -> SsuA
Description: Translation of SsuA
Type: translation
Pathway Components: ssuEADCB_mRNA -> SsuA
Components:
Function Name Type Evidence Reference(s)
product SsuA protein nd nd
reactant ssuEADCB_mRNA RNA nd nd
SsuC + SsuA + SsuB SsuA-SsuC-SsuB
Name: SsuC + SsuA + SsuB -> SsuA-SsuC-SsuB
Description: Reaction transforming SsuC, SsuA, SsuB into SsuA-SsuC-SsuB
Type: state transition
Pathway Components: SsuC + SsuA + SsuB -> SsuA-SsuC-SsuB
Components:
Function Name Type Evidence Reference(s)
reactant SsuA protein nd nd
product SsuA-SsuC-SsuB complex nd nd
reactant SsuB protein nd nd
reactant SsuC protein nd nd
SsuA-SsuC-SsuB aliphatic sulfonate_Ext aliphatic sulfonate
Name: aliphatic sulfonate_Ext -> aliphatic sulfonate
Description: Transport of aliphatic sulfonate_Ext through a bacterial membrane, leading to the presence of aliphatic sulfonate inside the cell.
Type: transport
Pathway Components: aliphatic sulfonate_Ext - SsuA-SsuC-SsuB -> aliphatic sulfonate
Components:
Function Name Type Evidence Reference(s)
catalyzer SsuA-SsuC-SsuB complex nd nd
product aliphatic sulfonate simple_molecule nd nd
reactant aliphatic sulfonate_Ext simple_molecule nd nd
ssuEADCB_mRNA SsuD
Name: ssuEADCB_mRNA -> SsuD
Description: Translation of SsuD
Type: translation
Pathway Components: ssuEADCB_mRNA -> SsuD
Components:
Function Name Type Evidence Reference(s)
product SsuD protein nd nd
reactant ssuEADCB_mRNA RNA nd nd
SsuD alkanesulfonate + Reduced FMN + oxygen flavin mononucleotide + sulfite + RCHO
Name: alkanesulfonate + Reduced FMN + oxygen -> flavin mononucleotide + sulfite + RCHO
Description: Reaction transforming alkanesulfonate, Reduced FMN, oxygen into flavin mononucleotide, sulfite , RCHO
Type: state transition
Pathway Components: alkanesulfonate + Reduced FMN + oxygen - SsuD -> flavin mononucleotide + sulfite + RCHO
Components:
Function Name Type Evidence Reference(s)
product RCHO simple_molecule nd nd
reactant Reduced FMN simple_molecule nd nd
catalyzer SsuD protein nd nd
reactant alkanesulfonate simple_molecule nd nd
product flavin mononucleotide simple_molecule nd nd
reactant oxygen simple_molecule nd nd
product sulfite simple_molecule nd nd
SsuD Reduced FMN + oxygen + MOPS Products
Name: Reduced FMN + oxygen + MOPS -> flavin mononucleotide + 3-morpholinopropanal + sulfite
Description: Reaction transforming Reduced FMN, oxygen, MOPS into flavin mononucleotide, 3-morpholinopropanal , sulfite
Type: state transition
Pathway Components: Reduced FMN + oxygen + MOPS - SsuD -> flavin mononucleotide + 3-morpholinopropanal + sulfite
Components:
Function Name Type Evidence Reference(s)
product 3-morpholinopropanal simple_molecule nd nd
reactant MOPS simple_molecule nd nd
reactant Reduced FMN simple_molecule nd nd
catalyzer SsuD protein nd nd
product flavin mononucleotide simple_molecule nd nd
reactant oxygen simple_molecule nd nd
product sulfite simple_molecule nd nd
SsuD butanesulfonate + Reduced FMN + oxygen flavin mononucleotide + sulfite + butanal
Name: butanesulfonate + Reduced FMN + oxygen -> flavin mononucleotide + sulfite + butanal
Description: Reaction transforming butanesulfonate, Reduced FMN, oxygen into flavin mononucleotide, sulfite , butanal
Type: state transition
Pathway Components: butanesulfonate + Reduced FMN + oxygen - SsuD -> flavin mononucleotide + sulfite + butanal
Components:
Function Name Type Evidence Reference(s)
reactant Reduced FMN simple_molecule nd nd
catalyzer SsuD protein nd nd
product butanal simple_molecule nd nd
reactant butanesulfonate simple_molecule nd nd
product flavin mononucleotide simple_molecule nd nd
reactant oxygen simple_molecule nd nd
product sulfite simple_molecule nd nd
SsuD Reduced FMN + isethionate + oxygen flavin mononucleotide + glycoaldehyde + sulfite
Name: Reduced FMN + isethionate + oxygen -> flavin mononucleotide + glycoaldehyde + sulfite
Description: Reaction transforming Reduced FMN, isethionate, oxygen into flavin mononucleotide, glycoaldehyde , sulfite
Type: state transition
Pathway Components: Reduced FMN + isethionate + oxygen - SsuD -> flavin mononucleotide + glycoaldehyde + sulfite
Components:
Function Name Type Evidence Reference(s)
reactant Reduced FMN simple_molecule nd nd
catalyzer SsuD protein nd nd
product flavin mononucleotide simple_molecule nd nd
product glycoaldehyde simple_molecule nd nd
reactant isethionate simple_molecule nd nd
reactant oxygen simple_molecule nd nd
product sulfite simple_molecule nd nd
ssuEADCB_mRNA SsuC
Name: ssuEADCB_mRNA -> SsuC
Description: Translation of SsuC
Type: translation
Pathway Components: ssuEADCB_mRNA -> SsuC
Components:
Function Name Type Evidence Reference(s)
product SsuC protein nd nd
reactant ssuEADCB_mRNA RNA nd nd
ssuEADCB_mRNA SsuB
Name: ssuEADCB_mRNA -> SsuB
Description: Translation of SsuB
Type: translation
Pathway Components: ssuEADCB_mRNA -> SsuB
Components:
Function Name Type Evidence Reference(s)
product SsuB protein nd nd
reactant ssuEADCB_mRNA RNA nd nd



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