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CdaR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
2-P-D-glycerate KDG CdaR mucate mucate_Ext glucarate glucarate_Ext D-glycerate D-glycerate_Ext GarD GarK GarL GarP GarR GudD GudP GudX RnpB ssRNA a tRNA precursor with a 5' extension a tRNA precursor with a 5' extension and a short 3' extension a tRNA precursor with a short 3' extension an uncharged tRNA cdaR cdaR_mRNA garD garD_mRNA garPLRK-rnpB garPLRK-rnpB_mRNA gudPXD gudPXD_mRNA pyruvate tartronate semialdehyde L-idarate


Gensor Unit       
Name: CdaR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:0042838 - D-glucarate catabolic process
GO:0006820 - anion transport
GO:0044248 - cellular catabolic process
GO:0046392 - galactarate catabolic process
GO:0019394 - glucarate catabolic process
GO:0045893 - positive regulation of transcription, DNA-templated
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cellular_component GO:0005737 - cytoplasm
GO:0016021 - integral component of membrane
GO:0005886 - plasma membrane
molecular_function GO:0008672 - 2-dehydro-3-deoxyglucarate aldolase activity
GO:0008679 - 2-hydroxy-3-oxopropionate reductase activity
GO:0003677 - DNA binding
GO:0003700 - DNA binding transcription factor activity
GO:0016832 - aldehyde-lyase activity
GO:0016830 - carbon-carbon lyase activity
GO:0008867 - galactarate dehydratase activity
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Components: Show/Hide Components Table (35 more...)
Function Name Type
simple_molecule 2-P-D-glycerate simple_molecule
simple_molecule 5-KDG simple_molecule
protein CdaR protein
protein GarD protein
protein GarK protein
protein GarL protein
protein GarP protein
protein GarR protein
protein GudD protein
protein GudP protein
protein GudX protein
protein RNA:RnpB protein
protein RnpB protein
gene cdaR gene
RNA cdaR_mRNA RNA
gene garD gene
RNA garD_mRNA RNA
gene garPLRK-rnpB gene
RNA garPLRK-rnpB_mRNA RNA
simple_molecule glucarate simple_molecule
simple_molecule glucarate_Ext simple_molecule
simple_molecule glycerate simple_molecule
simple_molecule glycerate_Ext simple_molecule
gene gudPXD gene
RNA gudPXD_mRNA RNA
simple_molecule idarate simple_molecule
simple_molecule mucate simple_molecule
simple_molecule mucate_Ext simple_molecule
simple_molecule pyruvate simple_molecule
simple_molecule single-stranded RNA simple_molecule
simple_molecule tRNA precursor with a 5' extension simple_molecule
simple_molecule tRNA precursor with a 5' extension and a short 3' extension simple_molecule
simple_molecule tRNA precursor with a short 3' extension simple_molecule
simple_molecule tartronate-S-ald simple_molecule
simple_molecule uncharged tRNA simple_molecule


Reactions       
Showing 27 reactions
CdaR cdaR cdaR_mRNA
Name: cdaR -> cdaR_mRNA
Description: Transcription of transcription unit cdaR. Reaction activation by CdaR.
Type: transcription
Pathway Components: cdaR - CdaR -> cdaR_mRNA
Components:
Function Name Type Evidence Reference(s)
activator CdaR protein nd nd
reactant cdaR gene nd nd
product cdaR_mRNA RNA nd nd
CdaR garD garD_mRNA
Name: garD -> garD_mRNA
Description: Transcription of transcription unit garD. Reaction activation by CdaR.
Type: transcription
Pathway Components: garD - CdaR -> garD_mRNA
Components:
Function Name Type Evidence Reference(s)
activator CdaR protein nd nd
reactant garD gene nd nd
product garD_mRNA RNA nd nd
CdaR garPLRK-rnpB garPLRK-rnpB_mRNA
Name: garPLRK-rnpB -> garPLRK-rnpB_mRNA
Description: Transcription of transcription unit garPLRK-rnpB. Reaction activation by CdaR.
Type: transcription
Pathway Components: garPLRK-rnpB - CdaR -> garPLRK-rnpB_mRNA
Components:
Function Name Type Evidence Reference(s)
activator CdaR protein nd nd
reactant garPLRK-rnpB gene nd nd
product garPLRK-rnpB_mRNA RNA nd nd
CdaR gudPXD gudPXD_mRNA
Name: gudPXD -> gudPXD_mRNA
Description: Transcription of transcription unit gudPXD. Reaction activation by CdaR.
Type: transcription
Pathway Components: gudPXD - CdaR -> gudPXD_mRNA
Components:
Function Name Type Evidence Reference(s)
activator CdaR protein nd nd
reactant gudPXD gene nd nd
product gudPXD_mRNA RNA nd nd
garPLRK-rnpB_mRNA GarP
Name: garPLRK-rnpB_mRNA -> GarP
Description: Translation of GarP
Type: translation
Pathway Components: garPLRK-rnpB_mRNA -> GarP
Components:
Function Name Type Evidence Reference(s)
product GarP protein nd nd
reactant garPLRK-rnpB_mRNA RNA nd nd
GarP GudP glycerate_Ext glycerate
Name: glycerate_Ext -> glycerate
Description: Transport of glycerate_Ext through a bacterial membrane, leading to the presence of glycerate inside the cell.
Type: transport
Pathway Components: glycerate_Ext - GarP - GudP -> glycerate
Components:
Function Name Type Evidence Reference(s)
catalyzer GarP protein nd nd
catalyzer GudP protein nd nd
product glycerate simple_molecule nd nd
reactant glycerate_Ext simple_molecule nd nd
GarP GudP glucarate_Ext glucarate
Name: glucarate_Ext -> glucarate
Description: Transport of glucarate_Ext through a bacterial membrane, leading to the presence of glucarate inside the cell.
Type: transport
Pathway Components: glucarate_Ext - GarP - GudP -> glucarate
Components:
Function Name Type Evidence Reference(s)
catalyzer GarP protein nd nd
catalyzer GudP protein nd nd
product glucarate simple_molecule nd nd
reactant glucarate_Ext simple_molecule nd nd
GarP GudP mucate_Ext mucate
Name: mucate_Ext -> mucate
Description: Transport of mucate_Ext through a bacterial membrane, leading to the presence of mucate inside the cell.
Type: transport
Pathway Components: mucate_Ext - GarP - GudP -> mucate
Components:
Function Name Type Evidence Reference(s)
catalyzer GarP protein nd nd
catalyzer GudP protein nd nd
product mucate simple_molecule nd nd
reactant mucate_Ext simple_molecule nd nd
garPLRK-rnpB_mRNA GarL
Name: garPLRK-rnpB_mRNA -> GarL
Description: Translation of GarL
Type: translation
Pathway Components: garPLRK-rnpB_mRNA -> GarL
Components:
Function Name Type Evidence Reference(s)
product GarL protein nd nd
reactant garPLRK-rnpB_mRNA RNA nd nd
GarL glucarate mucate 5-KDG tartronate-S-ald + pyruvate
Name: 5-KDG -> tartronate-S-ald + pyruvate
Description: Reaction transforming 5-KDG into tartronate-S-ald, pyruvate
Type: state transition
Pathway Components: 5-KDG - GarL - glucarate - mucate -> tartronate-S-ald + pyruvate
Components:
Function Name Type Evidence Reference(s)
reactant 5-KDG simple_molecule nd nd
catalyzer GarL protein nd nd
inhibitor glucarate simple_molecule nd nd
inhibitor mucate simple_molecule nd nd
product pyruvate simple_molecule nd nd
product tartronate-S-ald simple_molecule nd nd
garPLRK-rnpB_mRNA GarR
Name: garPLRK-rnpB_mRNA -> GarR
Description: Translation of GarR
Type: translation
Pathway Components: garPLRK-rnpB_mRNA -> GarR
Components:
Function Name Type Evidence Reference(s)
product GarR protein nd nd
reactant garPLRK-rnpB_mRNA RNA nd nd
GarR tartronate-S-ald glycerate
Name: tartronate-S-ald -> glycerate
Description: Reaction transforming tartronate-S-ald into glycerate
Type: state transition
Pathway Components: tartronate-S-ald - GarR -> glycerate
Components:
Function Name Type Evidence Reference(s)
catalyzer GarR protein nd nd
product glycerate simple_molecule nd nd
reactant tartronate-S-ald simple_molecule nd nd
GarR glycerate tartronate-S-ald
Name: glycerate -> tartronate-S-ald
Description: Reaction transforming glycerate into tartronate-S-ald
Type: state transition
Pathway Components: glycerate - GarR -> tartronate-S-ald
Components:
Function Name Type Evidence Reference(s)
catalyzer GarR protein nd nd
reactant glycerate simple_molecule nd nd
product tartronate-S-ald simple_molecule nd nd
garPLRK-rnpB_mRNA GarK
Name: garPLRK-rnpB_mRNA -> GarK
Description: Translation of GarK
Type: translation
Pathway Components: garPLRK-rnpB_mRNA -> GarK
Components:
Function Name Type Evidence Reference(s)
product GarK protein nd nd
reactant garPLRK-rnpB_mRNA RNA nd nd
GarK glycerate 2-P-D-glycerate
Name: glycerate -> 2-P-D-glycerate
Description: Reaction transforming glycerate into 2-P-D-glycerate
Type: state transition
Pathway Components: glycerate - GarK -> 2-P-D-glycerate
Components:
Function Name Type Evidence Reference(s)
product 2-P-D-glycerate simple_molecule nd nd
catalyzer GarK protein nd nd
reactant glycerate simple_molecule nd nd
garPLRK-rnpB_mRNA RNA:RnpB
Name: garPLRK-rnpB_mRNA -> RNA:RnpB
Description: Translation of RNA:RnpB
Type: translation
Pathway Components: garPLRK-rnpB_mRNA -> RNA:RnpB
Components:
Function Name Type Evidence Reference(s)
product RNA:RnpB protein nd nd
reactant garPLRK-rnpB_mRNA RNA nd nd
RNA:RnpB RnpB tRNA precursor with a 5' extension single-stranded RNA + uncharged tRNA
Name: tRNA precursor with a 5' extension -> single-stranded RNA + uncharged tRNA
Description: Reaction transforming tRNA precursor with a 5' extension into single-stranded RNA, uncharged tRNA
Type: state transition
Pathway Components: tRNA precursor with a 5' extension - RNA:RnpB - RnpB -> single-stranded RNA + uncharged tRNA
Components:
Function Name Type Evidence Reference(s)
catalyzer RNA:RnpB protein nd nd
catalyzer RnpB protein nd nd
product single-stranded RNA simple_molecule nd nd
reactant tRNA precursor with a 5' extension simple_molecule nd nd
product uncharged tRNA simple_molecule nd nd
RNA:RnpB RnpB Reactants Products
Name: tRNA precursor with a 5' extension and a short 3' extension -> tRNA precursor with a short 3' extension + single-stranded RNA
Description: Reaction transforming tRNA precursor with a 5' extension and a short 3' extension into tRNA precursor with a short 3' extension, single-stranded RNA
Type: state transition
Pathway Components: tRNA precursor with a 5' extension and a short 3' extension - RNA:RnpB - RnpB -> tRNA precursor with a short 3' extension + single-stranded RNA
Components:
Function Name Type Evidence Reference(s)
catalyzer RNA:RnpB protein nd nd
catalyzer RnpB protein nd nd
product single-stranded RNA simple_molecule nd nd
reactant tRNA precursor with a 5' extension and a short 3' extension simple_molecule nd nd
product tRNA precursor with a short 3' extension simple_molecule nd nd
garPLRK-rnpB_mRNA RnpB
Name: garPLRK-rnpB_mRNA -> RnpB
Description: Translation of RnpB
Type: translation
Pathway Components: garPLRK-rnpB_mRNA -> RnpB
Components:
Function Name Type Evidence Reference(s)
product RnpB protein nd nd
reactant garPLRK-rnpB_mRNA RNA nd nd
garD_mRNA GarD
Name: garD_mRNA -> GarD
Description: Translation of GarD
Type: translation
Pathway Components: garD_mRNA -> GarD
Components:
Function Name Type Evidence Reference(s)
product GarD protein nd nd
reactant garD_mRNA RNA nd nd
GarD mucate 5-KDG
Name: mucate -> 5-KDG
Description: Reaction transforming mucate into 5-KDG
Type: state transition
Pathway Components: mucate - GarD -> 5-KDG
Components:
Function Name Type Evidence Reference(s)
product 5-KDG simple_molecule nd nd
catalyzer GarD protein nd nd
reactant mucate simple_molecule nd nd
gudPXD_mRNA GudP
Name: gudPXD_mRNA -> GudP
Description: Translation of GudP
Type: translation
Pathway Components: gudPXD_mRNA -> GudP
Components:
Function Name Type Evidence Reference(s)
product GudP protein nd nd
reactant gudPXD_mRNA RNA nd nd
gudPXD_mRNA GudX
Name: gudPXD_mRNA -> GudX
Description: Translation of GudX
Type: translation
Pathway Components: gudPXD_mRNA -> GudX
Components:
Function Name Type Evidence Reference(s)
product GudX protein nd nd
reactant gudPXD_mRNA RNA nd nd
gudPXD_mRNA GudD
Name: gudPXD_mRNA -> GudD
Description: Translation of GudD
Type: translation
Pathway Components: gudPXD_mRNA -> GudD
Components:
Function Name Type Evidence Reference(s)
product GudD protein nd nd
reactant gudPXD_mRNA RNA nd nd
GudD idarate glucarate
Name: idarate -> glucarate
Description: Reaction transforming idarate into glucarate
Type: state transition
Pathway Components: idarate - GudD -> glucarate
Components:
Function Name Type Evidence Reference(s)
catalyzer GudD protein nd nd
product glucarate simple_molecule nd nd
reactant idarate simple_molecule nd nd
GudD mucate glucarate 5-KDG
Name: glucarate -> 5-KDG
Description: Reaction transforming glucarate into 5-KDG
Type: state transition
Pathway Components: glucarate - GudD - mucate -> 5-KDG
Components:
Function Name Type Evidence Reference(s)
product 5-KDG simple_molecule nd nd
catalyzer GudD protein nd nd
reactant glucarate simple_molecule nd nd
inhibitor mucate simple_molecule nd nd
cdaR_mRNA CdaR
Name: cdaR_mRNA -> CdaR
Description: Translation of CdaR
Type: translation
Pathway Components: cdaR_mRNA -> CdaR
Components:
Function Name Type Evidence Reference(s)
product CdaR protein nd nd
reactant cdaR_mRNA RNA nd nd



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