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CadC Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
CO2 CadA CadB CadC L-lysine L-lysine_Ext cadBA cadBA_mRNA cadC cadC_mRNA BioDex 1- BioDex 1-_Ext


Gensor Unit       
Name: CadC
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:1903401 - L-lysine transmembrane transport
GO:0015839 - cadaverine transport
GO:1990451 - cellular stress response to acidic pH
GO:0006554 - lysine catabolic process
GO:0045893 - positive regulation of transcription, DNA-templated
cellular_component GO:0005887 - integral component of plasma membrane
GO:0005622 - intracellular
GO:0016020 - membrane
GO:0005886 - plasma membrane
molecular_function GO:0015297 - antiporter activity
GO:0097216 - guanosine tetraphosphate binding
GO:0042802 - identical protein binding
GO:0008923 - lysine decarboxylase activity
GO:0043872 - lysine:cadaverine antiporter activity
GO:0005515 - protein binding
GO:0015295 - solute:proton symporter activity
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Components: Show/Hide Components Table (12 more...)
Function Name Type
simple_molecule BioDex 1- simple_molecule
simple_molecule BioDex 1-_Ext simple_molecule
simple_molecule CO2 simple_molecule
protein CadA protein
protein CadB protein
protein CadC protein
gene cadBA gene
RNA cadBA_mRNA RNA
gene cadC gene
RNA cadC_mRNA RNA
simple_molecule lysine simple_molecule
simple_molecule lysine_Ext simple_molecule


Reactions       
Showing 8 reactions
CadC cadBA cadBA_mRNA
Name: cadBA -> cadBA_mRNA
Description: Transcription of transcription unit cadBA. Reaction activation by CadC.
Type: transcription
Pathway Components: cadBA - CadC -> cadBA_mRNA
Components:
Function Name Type Evidence Reference(s)
activator CadC protein nd nd
reactant cadBA gene nd nd
product cadBA_mRNA RNA nd nd
CadC cadC cadC_mRNA
Name: cadC -> cadC_mRNA
Description: Transcription of transcription unit cadC. Reaction activation by CadC.
Type: transcription
Pathway Components: cadC - CadC -> cadC_mRNA
Components:
Function Name Type Evidence Reference(s)
activator CadC protein nd nd
reactant cadC gene nd nd
product cadC_mRNA RNA nd nd
cadC_mRNA CadC
Name: cadC_mRNA -> CadC
Description: Translation of CadC
Type: translation
Pathway Components: cadC_mRNA -> CadC
Components:
Function Name Type Evidence Reference(s)
product CadC protein nd nd
reactant cadC_mRNA RNA nd nd
cadBA_mRNA CadB
Name: cadBA_mRNA -> CadB
Description: Translation of CadB
Type: translation
Pathway Components: cadBA_mRNA -> CadB
Components:
Function Name Type Evidence Reference(s)
product CadB protein nd nd
reactant cadBA_mRNA RNA nd nd
CadB lysine BioDex 1-_Ext BioDex 1-
Name: BioDex 1-_Ext -> BioDex 1-
Description: Transport of BioDex 1-_Ext through a bacterial membrane, leading to the presence of BioDex 1- inside the cell.
Type: transport
Pathway Components: BioDex 1-_Ext - CadB - lysine -> BioDex 1-
Components:
Function Name Type Evidence Reference(s)
product BioDex 1- simple_molecule nd nd
reactant BioDex 1-_Ext simple_molecule nd nd
catalyzer CadB protein nd nd
inhibitor lysine simple_molecule nd nd
CadB BioDex 1-_Ext + lysine_Ext BioDex 1- + lysine
Name: BioDex 1-_Ext + lysine_Ext -> BioDex 1- + lysine
Description: Transport of BioDex 1-_Ext, lysine_Ext through a bacterial membrane, leading to the presence of BioDex 1-, lysine inside the cell.
Type: transport
Pathway Components: BioDex 1-_Ext + lysine_Ext - CadB -> BioDex 1- + lysine
Components:
Function Name Type Evidence Reference(s)
product BioDex 1- simple_molecule nd nd
reactant BioDex 1-_Ext simple_molecule nd nd
catalyzer CadB protein nd nd
product lysine simple_molecule nd nd
reactant lysine_Ext simple_molecule nd nd
cadBA_mRNA CadA
Name: cadBA_mRNA -> CadA
Description: Translation of CadA
Type: translation
Pathway Components: cadBA_mRNA -> CadA
Components:
Function Name Type Evidence Reference(s)
product CadA protein nd nd
reactant cadBA_mRNA RNA nd nd
CadA lysine BioDex 1- + CO2
Name: lysine -> BioDex 1- + CO2
Description: Reaction transforming lysine into BioDex 1-, CO2
Type: state transition
Pathway Components: lysine - CadA -> BioDex 1- + CO2
Components:
Function Name Type Evidence Reference(s)
product BioDex 1- simple_molecule nd nd
product CO2 simple_molecule nd nd
catalyzer CadA protein nd nd
reactant lysine simple_molecule nd nd



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