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AtoC Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          


Gensor Unit       
Name: AtoC
Signal name: acetoacetate
spermidine.
Classification:
Groups: GUs related to the two-component system
Gene Ontology Terms (GO): biological_process GO:0043442 - acetoacetic acid catabolic process
GO:0006635 - fatty acid beta-oxidation
GO:0051289 - protein homotetramerization
cellular_component GO:0005886 - plasma membrane
molecular_function GO:0008775 - acetate CoA-transferase activity
GO:0003985 - acetyl-CoA C-acetyltransferase activity
GO:0003988 - acetyl-CoA C-acyltransferase activity
GO:0042802 - identical protein binding
GO:0005515 - protein binding
Components: Show/Hide Components Table (16 more...)
Function Name Type
protein AtoA protein
complex AtoA-AtoD complex
protein AtoB protein
protein AtoC protein
complex AtoC-phosphate complex
protein AtoD protein
protein AtoE protein
simple_molecule acetate simple_molecule
simple_molecule acetoacetyl-CoA simple_molecule
simple_molecule acetyl-CoA simple_molecule
gene atoDAEB gene
RNA atoDAEB_mRNA RNA
simple_molecule coenzyme A simple_molecule
simple_molecule oxobutyrate simple_molecule
simple_molecule oxobutyrate_Ext simple_molecule
simple_molecule phosphate simple_molecule


Reactions       
Showing 10 reactions
phosphate + AtoC AtoC-phosphate
Name: phosphate + AtoC -> AtoC-phosphate
Description: Reaction transforming phosphate, AtoC into AtoC-phosphate
Type: state transition
Pathway Components: phosphate + AtoC -> AtoC-phosphate
Components:
Function Name Type Evidence Reference(s)
reactant AtoC protein nd nd
product AtoC-phosphate complex nd nd
reactant phosphate simple_molecule nd nd
AtoC-phosphate atoDAEB atoDAEB_mRNA
Name: atoDAEB -> atoDAEB_mRNA
Description: Transcription of transcription unit atoDAEB. Reaction activation by AtoC-phosphate.
Type: transcription
Pathway Components: atoDAEB - AtoC-phosphate -> atoDAEB_mRNA
Components:
Function Name Type Evidence Reference(s)
activator AtoC-phosphate complex nd nd
reactant atoDAEB gene nd nd
product atoDAEB_mRNA RNA nd nd
atoDAEB_mRNA AtoD
Name: atoDAEB_mRNA -> AtoD
Description: Translation of AtoD
Type: translation
Pathway Components: atoDAEB_mRNA -> AtoD
Components:
Function Name Type Evidence Reference(s)
product AtoD protein nd nd
reactant atoDAEB_mRNA RNA nd nd
AtoD + AtoA AtoA-AtoD
Name: AtoD + AtoA -> AtoA-AtoD
Description: Reaction transforming AtoD, AtoA into AtoA-AtoD
Type: state transition
Pathway Components: AtoD + AtoA -> AtoA-AtoD
Components:
Function Name Type Evidence Reference(s)
reactant AtoA protein nd nd
product AtoA-AtoD complex nd nd
reactant AtoD protein nd nd
AtoA-AtoD acetyl-CoA coenzyme A oxobutyrate + acetyl-CoA acetoacetyl-CoA + acetate
Name: oxobutyrate + acetyl-CoA -> acetoacetyl-CoA + acetate
Description: Reaction transforming oxobutyrate, acetyl-CoA into acetoacetyl-CoA, acetate
Type: state transition
Pathway Components: oxobutyrate + acetyl-CoA - AtoA-AtoD - acetyl-CoA - coenzyme A -> acetoacetyl-CoA + acetate
Components:
Function Name Type Evidence Reference(s)
catalyzer AtoA-AtoD complex nd nd
product acetate simple_molecule nd nd
product acetoacetyl-CoA simple_molecule nd nd
inhibitor acetyl-CoA simple_molecule nd nd
reactant acetyl-CoA simple_molecule nd nd
inhibitor coenzyme A simple_molecule nd nd
reactant oxobutyrate simple_molecule nd nd
atoDAEB_mRNA AtoA
Name: atoDAEB_mRNA -> AtoA
Description: Translation of AtoA
Type: translation
Pathway Components: atoDAEB_mRNA -> AtoA
Components:
Function Name Type Evidence Reference(s)
product AtoA protein nd nd
reactant atoDAEB_mRNA RNA nd nd
atoDAEB_mRNA AtoE
Name: atoDAEB_mRNA -> AtoE
Description: Translation of AtoE
Type: translation
Pathway Components: atoDAEB_mRNA -> AtoE
Components:
Function Name Type Evidence Reference(s)
product AtoE protein nd nd
reactant atoDAEB_mRNA RNA nd nd
AtoE oxobutyrate_Ext oxobutyrate
Name: oxobutyrate_Ext -> oxobutyrate
Description: Transport of oxobutyrate_Ext through a bacterial membrane, leading to the presence of oxobutyrate inside the cell.
Type: transport
Pathway Components: oxobutyrate_Ext - AtoE -> oxobutyrate
Components:
Function Name Type Evidence Reference(s)
catalyzer AtoE protein nd nd
product oxobutyrate simple_molecule nd nd
reactant oxobutyrate_Ext simple_molecule nd nd
atoDAEB_mRNA AtoB
Name: atoDAEB_mRNA -> AtoB
Description: Translation of AtoB
Type: translation
Pathway Components: atoDAEB_mRNA -> AtoB
Components:
Function Name Type Evidence Reference(s)
product AtoB protein nd nd
reactant atoDAEB_mRNA RNA nd nd
AtoB acetoacetyl-CoA acetyl-CoA acetoacetyl-CoA + coenzyme A
Name: acetyl-CoA -> acetoacetyl-CoA + coenzyme A
Description: Reaction transforming acetyl-CoA into acetoacetyl-CoA, coenzyme A
Type: state transition
Pathway Components: acetyl-CoA - AtoB - acetoacetyl-CoA -> acetoacetyl-CoA + coenzyme A
Components:
Function Name Type Evidence Reference(s)
catalyzer AtoB protein nd nd
inhibitor acetoacetyl-CoA simple_molecule nd nd
product acetoacetyl-CoA simple_molecule nd nd
reactant acetyl-CoA simple_molecule nd nd
product coenzyme A simple_molecule nd nd



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