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AsnC Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
5,10-methylenetetrahydrofolate dihydrofolate AsnA AsnC GDP GTP L-asparagine asp MioC MnmE MnmG a tRNA 2-thiouridine34 a 5-aminomethyl-2-thiouridine in tRNA a 5-carboxymethylaminomethyl-2-thiouridine in tRNA a 5-carboxymethylaminomethyluridine in tRNA a tRNA uridine34 ammonium asnA asnA_mRNA asnC asnC-mioC asnC-mioC-mnmG asnC-mioC-mnmG_mRNA asnC-mioC_mRNA asnC_mRNA PP glycine phosphate AsnC L-asparagine MnmE MnmG GDP phosphate GTP dihydrofolate


Gensor Unit       
Name: AsnC
Classification:
Groups: GUs related to the metabolism of amino acids
Gene Ontology Terms (GO): GO:0010181 - FMN binding
GO:0008033 - tRNA processing
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0045892 - negative regulation of transcription, DNA-templated
GO:0016491 - oxidoreductase activity
GO:0008652 - cellular amino acid biosynthetic process
GO:0005622 - intracellular
GO:0004812 - aminoacyl-tRNA ligase activity
GO:0030488 - tRNA methylation
GO:0005737 - cytoplasm
GO:0045893 - positive regulation of transcription, DNA-templated
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Components:
Function Name Type
simple molecule phosphate simple molecule


Reactions       
Showing 14 reactions
asnA asnA_mRNA
Name: asnA -> asnA_mRNA
Description: Transcription of transcription unit asnA; reaction activation by AsnC.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant asnA gene nd nd
product asnA_mRNA RNA nd nd
asnC asnC_mRNA
Name: asnC -> asnC_mRNA
Description: Transcription of transcription unit asnC; reaction inhibition by AsnC.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product asnC_mRNA RNA nd nd
reactant asnC gene nd nd
asnC-mioC asnC-mioC_mRNA
Name: asnC-mioC -> asnC-mioC_mRNA
Description: Transcription of transcription unit asnC-mioC; reaction inhibition by AsnC.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product asnC-mioC_mRNA RNA nd nd
reactant asnC-mioC gene nd nd
asnC-mioC-mnmG asnC-mioC-mnmG_mRNA
Name: asnC-mioC-mnmG -> asnC-mioC-mnmG_mRNA
Description: Transcription of transcription unit asnC-mioC-mnmG; reaction inhibition by AsnC.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant asnC-mioC-mnmG gene nd nd
product asnC-mioC-mnmG_mRNA RNA nd nd
AsnC + L-asparagine AsnC-L-asparagine
Name: AsnC + L-asparagine -> AsnC-L-asparagine
Description: Reaction transforming AsnC, L-asparagine into AsnC-L-asparagine
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product AsnC-L-asparagine complex nd nd
reactant AsnC protein nd nd
reactant L-asparagine simple molecule nd nd
asnC-mioC-mnmG_mRNA AsnC
Name: asnC-mioC-mnmG_mRNA -> AsnC
Description: Translation of AsnC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product AsnC protein nd nd
reactant asnC-mioC-mnmG_mRNA RNA nd nd
asnA_mRNA AsnA
Name: asnA_mRNA -> AsnA
Description: Translation of AsnA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product AsnA protein nd nd
reactant asnA_mRNA RNA nd nd
asp + ammonium L-asparagine + PP
Name: asp + ammonium -> L-asparagine + PP
Description: Reaction transforming asp, ammonium into L-asparagine, PP
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant ammonium simple molecule nd nd
product L-asparagine simple molecule nd nd
reactant asp simple molecule nd nd
product PP simple molecule nd nd
asnC-mioC-mnmG_mRNA MioC
Name: asnC-mioC-mnmG_mRNA -> MioC
Description: Translation of MioC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MioC protein nd nd
reactant asnC-mioC-mnmG_mRNA RNA nd nd
asnC-mioC-mnmG_mRNA MnmG
Name: asnC-mioC-mnmG_mRNA -> MnmG
Description: Translation of MnmG
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant asnC-mioC-mnmG_mRNA RNA nd nd
product MnmG protein nd nd
MnmE + MnmG MnmE-MnmG
Name: MnmE + MnmG -> MnmE-MnmG
Description: Reaction transforming MnmE, MnmG into MnmE-MnmG
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant MnmG protein nd nd
reactant MnmE protein nd nd
product MnmE-MnmG complex nd nd
a tRNA uridine34 + GTP + 5,10-methylenetetrahydrofolate + glycine a 5-carboxymethylaminomethyluridine in tRNA + GDP + phosphate + dihydrofolate
Name: a tRNA uridine34 + GTP + 5,10-methylenetetrahydrofolate + glycine -> a 5-carboxymethylaminomethyluridine in tRNA + GDP + phosphate + dihydrofolate
Description: Reaction transforming a tRNA uridine34, GTP, 5,10-methylenetetrahydrofolate, glycine into a 5-carboxymethylaminomethyluridine in tRNA, GDP , phosphate , dihydrofolate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant a tRNA uridine34 simple molecule nd nd
product a 5-carboxymethylaminomethyluridine in tRNA simple molecule nd nd
reactant GTP simple molecule nd nd
reactant glycine simple molecule nd nd
product dihydrofolate simple molecule nd nd
product phosphate simple molecule nd nd
reactant 5,10-methylenetetrahydrofolate simple molecule nd nd
product GDP simple molecule nd nd
a tRNA 2-thiouridine34 + GTP + glycine + 5,10-methylenetetrahydrofolate a 5-carboxymethylaminomethyl-2-thiouridine in tRNA + GDP + dihydrofolate + phosphate
Name: a tRNA 2-thiouridine34 + GTP + glycine + 5,10-methylenetetrahydrofolate -> a 5-carboxymethylaminomethyl-2-thiouridine in tRNA + GDP + dihydrofolate + phosphate
Description: Reaction transforming a tRNA 2-thiouridine34, GTP, glycine, 5,10-methylenetetrahydrofolate into a 5-carboxymethylaminomethyl-2-thiouridine in tRNA, GDP , dihydrofolate , phosphate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product GDP simple molecule nd nd
reactant 5,10-methylenetetrahydrofolate simple molecule nd nd
product dihydrofolate simple molecule nd nd
product phosphate simple molecule nd nd
reactant a tRNA 2-thiouridine34 simple molecule nd nd
reactant glycine simple molecule nd nd
product a 5-carboxymethylaminomethyl-2-thiouridine in tRNA simple molecule nd nd
reactant GTP simple molecule nd nd
a tRNA 2-thiouridine34 + 5,10-methylenetetrahydrofolate + ammonium + GTP a 5-aminomethyl-2-thiouridine in tRNA + dihydrofolate + GDP + phosphate
Name: a tRNA 2-thiouridine34 + 5,10-methylenetetrahydrofolate + ammonium + GTP -> a 5-aminomethyl-2-thiouridine in tRNA + dihydrofolate + GDP + phosphate
Description: Reaction transforming a tRNA 2-thiouridine34, 5,10-methylenetetrahydrofolate, ammonium, GTP into a 5-aminomethyl-2-thiouridine in tRNA, dihydrofolate , GDP , phosphate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant GTP simple molecule nd nd
reactant ammonium simple molecule nd nd
reactant a tRNA 2-thiouridine34 simple molecule nd nd
reactant 5,10-methylenetetrahydrofolate simple molecule nd nd
product dihydrofolate simple molecule nd nd
product a 5-aminomethyl-2-thiouridine in tRNA simple molecule nd nd
product GDP simple molecule nd nd
product phosphate simple molecule nd nd



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