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AsnC Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
5,10-methylenetetrahydrofolate dihydrofolate AsnA AsnC GDP GTP L-asparagine asp MioC MnmE MnmG a tRNA 2-thiouridine34 a 5-aminomethyl-2-thiouridine in tRNA a 5-carboxymethylaminomethyl-2-thiouridine in tRNA a 5-carboxymethylaminomethyluridine in tRNA a tRNA uridine34 ammonium asnA asnA_mRNA asnC asnC-mioC asnC-mioC-mnmG asnC-mioC-mnmG_mRNA asnC-mioC_mRNA asnC_mRNA PP glycine phosphate AsnC L-asparagine MnmE MnmG GDP phosphate GTP dihydrofolate


Gensor Unit       
Name: AsnC
Classification:
Groups: GUs related to the metabolism of amino acids
Gene Ontology Terms (GO): GO:0045892 - negative regulation of transcription, DNA-templated
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0005622 - intracellular
GO:0008652 - cellular amino acid biosynthetic process
GO:0010181 - FMN binding
GO:0016491 - oxidoreductase activity
GO:0008033 - tRNA processing
GO:0030488 - tRNA methylation
GO:0005737 - cytoplasm
GO:0004812 - aminoacyl-tRNA ligase activity
GO:0045893 - positive regulation of transcription, DNA-templated
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Components:
Function Name Type
simple molecule phosphate simple molecule


Reactions       
Showing 14 reactions
asnA asnA_mRNA
Name: asnA -> asnA_mRNA
Description: Transcription of transcription unit asnA; reaction activation by AsnC.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant asnA gene nd nd
product asnA_mRNA RNA nd nd
asnC asnC_mRNA
Name: asnC -> asnC_mRNA
Description: Transcription of transcription unit asnC; reaction inhibition by AsnC.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant asnC gene nd nd
product asnC_mRNA RNA nd nd
asnC-mioC asnC-mioC_mRNA
Name: asnC-mioC -> asnC-mioC_mRNA
Description: Transcription of transcription unit asnC-mioC; reaction inhibition by AsnC.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product asnC-mioC_mRNA RNA nd nd
reactant asnC-mioC gene nd nd
asnC-mioC-mnmG asnC-mioC-mnmG_mRNA
Name: asnC-mioC-mnmG -> asnC-mioC-mnmG_mRNA
Description: Transcription of transcription unit asnC-mioC-mnmG; reaction inhibition by AsnC.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product asnC-mioC-mnmG_mRNA RNA nd nd
reactant asnC-mioC-mnmG gene nd nd
AsnC + L-asparagine AsnC-L-asparagine
Name: AsnC + L-asparagine -> AsnC-L-asparagine
Description: Reaction transforming AsnC, L-asparagine into AsnC-L-asparagine
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant AsnC protein nd nd
product AsnC-L-asparagine complex nd nd
reactant L-asparagine simple molecule nd nd
asnC-mioC-mnmG_mRNA AsnC
Name: asnC-mioC-mnmG_mRNA -> AsnC
Description: Translation of AsnC
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant asnC-mioC-mnmG_mRNA RNA nd nd
product AsnC protein nd nd
asnA_mRNA AsnA
Name: asnA_mRNA -> AsnA
Description: Translation of AsnA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant asnA_mRNA RNA nd nd
product AsnA protein nd nd
asp + ammonium L-asparagine + PP
Name: asp + ammonium -> L-asparagine + PP
Description: Reaction transforming asp, ammonium into L-asparagine, PP
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant ammonium simple molecule nd nd
product L-asparagine simple molecule nd nd
reactant asp simple molecule nd nd
product PP simple molecule nd nd
asnC-mioC-mnmG_mRNA MioC
Name: asnC-mioC-mnmG_mRNA -> MioC
Description: Translation of MioC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MioC protein nd nd
reactant asnC-mioC-mnmG_mRNA RNA nd nd
asnC-mioC-mnmG_mRNA MnmG
Name: asnC-mioC-mnmG_mRNA -> MnmG
Description: Translation of MnmG
Type: translation
Components:
Function Name Type Evidence Reference(s)
product MnmG protein nd nd
reactant asnC-mioC-mnmG_mRNA RNA nd nd
MnmE + MnmG MnmE-MnmG
Name: MnmE + MnmG -> MnmE-MnmG
Description: Reaction transforming MnmE, MnmG into MnmE-MnmG
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product MnmE-MnmG complex nd nd
reactant MnmE protein nd nd
reactant MnmG protein nd nd
a tRNA uridine34 + GTP + 5,10-methylenetetrahydrofolate + glycine a 5-carboxymethylaminomethyluridine in tRNA + GDP + phosphate + dihydrofolate
Name: a tRNA uridine34 + GTP + 5,10-methylenetetrahydrofolate + glycine -> a 5-carboxymethylaminomethyluridine in tRNA + GDP + phosphate + dihydrofolate
Description: Reaction transforming a tRNA uridine34, GTP, 5,10-methylenetetrahydrofolate, glycine into a 5-carboxymethylaminomethyluridine in tRNA, GDP , phosphate , dihydrofolate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product phosphate simple molecule nd nd
reactant glycine simple molecule nd nd
product dihydrofolate simple molecule nd nd
product GDP simple molecule nd nd
product a 5-carboxymethylaminomethyluridine in tRNA simple molecule nd nd
reactant GTP simple molecule nd nd
reactant 5,10-methylenetetrahydrofolate simple molecule nd nd
reactant a tRNA uridine34 simple molecule nd nd
a tRNA 2-thiouridine34 + GTP + glycine + 5,10-methylenetetrahydrofolate a 5-carboxymethylaminomethyl-2-thiouridine in tRNA + GDP + dihydrofolate + phosphate
Name: a tRNA 2-thiouridine34 + GTP + glycine + 5,10-methylenetetrahydrofolate -> a 5-carboxymethylaminomethyl-2-thiouridine in tRNA + GDP + dihydrofolate + phosphate
Description: Reaction transforming a tRNA 2-thiouridine34, GTP, glycine, 5,10-methylenetetrahydrofolate into a 5-carboxymethylaminomethyl-2-thiouridine in tRNA, GDP , dihydrofolate , phosphate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant GTP simple molecule nd nd
reactant 5,10-methylenetetrahydrofolate simple molecule nd nd
product dihydrofolate simple molecule nd nd
product a 5-carboxymethylaminomethyl-2-thiouridine in tRNA simple molecule nd nd
product GDP simple molecule nd nd
reactant a tRNA 2-thiouridine34 simple molecule nd nd
reactant glycine simple molecule nd nd
product phosphate simple molecule nd nd
a tRNA 2-thiouridine34 + 5,10-methylenetetrahydrofolate + ammonium + GTP a 5-aminomethyl-2-thiouridine in tRNA + dihydrofolate + GDP + phosphate
Name: a tRNA 2-thiouridine34 + 5,10-methylenetetrahydrofolate + ammonium + GTP -> a 5-aminomethyl-2-thiouridine in tRNA + dihydrofolate + GDP + phosphate
Description: Reaction transforming a tRNA 2-thiouridine34, 5,10-methylenetetrahydrofolate, ammonium, GTP into a 5-aminomethyl-2-thiouridine in tRNA, dihydrofolate , GDP , phosphate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product a 5-aminomethyl-2-thiouridine in tRNA simple molecule nd nd
reactant GTP simple molecule nd nd
reactant a tRNA 2-thiouridine34 simple molecule nd nd
reactant 5,10-methylenetetrahydrofolate simple molecule nd nd
product GDP simple molecule nd nd
reactant ammonium simple molecule nd nd
product dihydrofolate simple molecule nd nd
product phosphate simple molecule nd nd



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