RegulonDB RegulonDB

ArsR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
Antimonite ArsB ArsC ArsR reduced glutaredoxin oxidized glutaredoxin arsRBC arsRBC_mRNA arsenate arsenite arsenite_Ext ArsR Antimonite ArsR arsenite


Gensor Unit       
Name: ArsR
Description: ArsR negatively regulates the expression of genes involved in detoxification of arsenic-containing substances in the absence of arsenite and antimonite. The presence of arsenite or antimonite induces the expression of genes related to the reduction of arsenate to arsenite and to arsenite efllux.
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:0015699 - antimonite transport
GO:0015700 - arsenite transport
GO:0006974 - cellular response to DNA damage stimulus
GO:0055114 - oxidation-reduction process
GO:0006355 - regulation of transcription, DNA-templated
GO:0046685 - response to arsenic-containing substance
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cellular_component GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0005622 - intracellular
GO:0016020 - membrane
GO:0005886 - plasma membrane
molecular_function GO:0003677 - DNA binding
GO:0042960 - antimonite secondary active transmembrane transporter activity
GO:0008794 - arsenate reductase (glutaredoxin) activity
GO:0008490 - arsenite secondary active transmembrane transporter activity
GO:0015105 - arsenite transmembrane transporter activity
GO:0016491 - oxidoreductase activity
GO:0003700 - transcription factor activity, sequence-specific DNA binding
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Components:
Function Name Type
simple molecule arsenite simple molecule</