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ArgP Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate tetrahydrodipicolinate ketoglutarate ArgO ArgP CDP CO2 DapB DapD DnaA DnaN GDP GdhA L-arginine asp L-aspartyl-4-P L-glutamate L-lysine L-lysine_Ext LysA LysC LysP N-Succinyl-2-L-amino-6-oxoheptanedioate NrdA NrdB RecF RecO RecR Udp YfaE a 2'-deoxyribonucleoside 5'-diphosphate a reduced thioredoxin nucleoside diphosphate a stabilized RecA filament-DNA complex ammonia oxidized thioredoxin an unstable RecA filament-DNA complex argO argO_mRNA argP argP_mRNA CoA dADP dCDP dGDP dUDP dapB dapB_mRNA dapD dapD_mRNA dnaAN-recF dnaAN-recF_mRNA gdhA gdhA_mRNA lysA lysA_mRNA lysC lysC_mRNA lysP lysP_mRNA M-DAP nrdAB-yfaE nrdAB-yfaE_mRNA suc-coa ArgP L-arginine ArgP L-lysine RecF RecR RecO NrdA NrdB oxidized thioredoxin a reduced thioredoxin a reduced thioredoxin oxidized thioredoxin dUTP


Gensor Unit       
Name: ArgP
Description: Molecular biology level
Detailed: In the absence of L-lysine, ArgP positively regulates the expression of genes required for lysine and glutamate biosynthetic process, DNA replication and recombination, and deoxyribonucleoside metabolic process. Under these conditions, ArgP binds its target sites enabling the expression of its regulated genes. In the presence of L-lysine, ArgP is modified to ArgP-L-lysine, binds its own promoter, preventing its own expression.
Less detailed: In the absence of L-lysine, ArgP positively regulates the expression of genes needed for lysine and glutamate biosynthetic processes, DNA replication and recombination, and deoxyribonucleoside metabolic process.

Physiology level
Detailed: The presence of L-lysine inhibits the expression of genes involved with lysine and glutamate biosynthetic process, DNA replication and recombination, and deoxyribonucleoside metabolic process. Under these condition the genes necessary for biosynthesis of L-lysine from M-DAP and tetrahydropicolinate, conversion of ketoglutarate to L-glutamate, oxidation of nucleosides and DNA recombination are expressed.
Less detailed: The presence of L-lysine induces the expression of genes needful for biosynthesis of L-lysine from M-DAP and tetrahydropicolinate, conversion of ketoglutarate to L-glutamate, oxidation of nucleosides and DNA recombination.
Classification:
Groups: GUs related to the metabolism of amino acids
Gene Ontology Terms (GO): biological_process GO:0071897 - DNA biosynthetic process
GO:0006260 - DNA replication
GO:0006270 - DNA replication initiation
GO:0006271 - DNA strand elongation involved in DNA replication
GO:0000731 - DNA synthesis involved in DNA repair
GO:1902023 - L-arginine transport
Read more >
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005887 - integral component of plasma membrane
GO:0005886 - plasma membrane
GO:0005971 - ribonucleoside-diphosphate reductase complex
molecular_function GO:0051537 - 2 iron, 2 sulfur cluster binding
GO:0008666 - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity
GO:0008839 - 4-hydroxy-tetrahydrodipicolinate reductase
GO:0005524 - ATP binding
GO:0003677 - DNA binding
GO:0003700 - DNA binding transcription factor activity
GO:0003688 - DNA replication origin binding
Read more >
Components: Show/Hide Components Table (91 more...)
Function Name Type
simple_molecule (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate simple_molecule
simple_molecule 5'-UMP simple_molecule
protein ArgO protein
protein ArgP protein
complex ArgP-arginine complex
complex ArgP-lysine complex
simple_molecule CO2 simple_molecule
protein DapB protein
protein DapD protein
protein DnaA protein
protein DnaE protein
protein DnaN protein
protein DnaQ protein
protein DnaX protein
protein GdhA protein
simple_molecule GlnB simple_molecule
protein GlnD protein
simple_molecule GlnK simple_molecule
protein HolA protein
protein HolB protein
protein HolC protein
protein HolD protein
protein HolE protein
complex HolE-DnaQ-DnaE-HolA-HolB-DnaX-DnaN-HolD-HolC complex
simple_molecule L-glutamate simple_molecule
protein LysA protein
protein LysC protein
protein LysP protein
simple_molecule M-DAP simple_molecule
protein Map protein
simple_molecule N-Succinyl-2-L-amino-6-oxoheptanedioate simple_molecule
protein NrdA protein
complex NrdA-NrdB complex
protein NrdB protein
protein RecF protein
complex RecF-RecR-RecO complex
protein RecO protein
protein RecR protein
simple_molecule YbaI simple_molecule
protein YfaE protein
simple_molecule ammonium simple_molecule
gene argO gene
RNA argO_mRNA RNA
gene argP gene
RNA argP_mRNA RNA
simple_molecule arginine simple_molecule
simple_molecule arginine_Ext simple_molecule
simple_molecule aspartate simple_molecule
simple_molecule aspartyl-4-P simple_molecule
simple_molecule coenzyme A simple_molecule
simple_molecule cytidine-diphosphate simple_molecule
simple_molecule dADP simple_molecule
simple_molecule dCDP simple_molecule
simple_molecule dGDP simple_molecule
simple_molecule dUDP simple_molecule
gene dapB gene
RNA dapB_mRNA RNA
gene dapD gene
RNA dapD_mRNA RNA
simple_molecule deoxynucleoside diphosphate simple_molecule
simple_molecule diphosphate simple_molecule
gene dnaAN-recF gene
RNA dnaAN-recF_mRNA RNA
gene gdhA gene
RNA gdhA_mRNA RNA
simple_molecule guanosine-diphosphate simple_molecule
simple_molecule ketoglutarate simple_molecule
gene lysA gene
RNA lysA_mRNA RNA
gene lysC gene
RNA lysC_mRNA RNA
gene lysP gene
RNA lysP_mRNA RNA
simple_molecule lysine simple_molecule
simple_molecule lysine_Ext simple_molecule
gene map-glnD-dapD gene
RNA map-glnD-dapD_mRNA RNA
simple_molecule methionine simple_molecule
gene nrdAB-yfaE gene
RNA nrdAB-yfaE_mRNA RNA
simple_molecule nucleoside diphosphate simple_molecule
simple_molecule peptide simple_molecule
simple_molecule peptide with an N-terminal L-methionine simple_molecule
simple_molecule reduced thioredoxin simple_molecule
simple_molecule stabilized RecA filament-DNA complex simple_molecule
simple_molecule suc-coa simple_molecule
simple_molecule tetrahydrodipicolinate simple_molecule
simple_molecule thioredoxin disulfide simple_molecule
simple_molecule unstable RecA filament-DNA complex simple_molecule
simple_molecule uridine-diphosphate simple_molecule
simple_molecule uridine-triphosphate simple_molecule


Reactions       
Showing 52 reactions
ArgP ArgP-arginine argO argO_mRNA
Name: argO -> argO_mRNA
Description: Transcription of transcription unit argO. Reaction activation by ArgP, and ArgP-arginine.
Type: transcription
Pathway Components: argO - ArgP - ArgP-arginine -> argO_mRNA
Components:
Function Name Type Evidence Reference(s)
activator ArgP protein nd nd
activator ArgP-arginine complex nd nd
reactant argO gene nd nd
product argO_mRNA RNA nd nd
ArgP ArgP-arginine dapB dapB_mRNA
Name: dapB -> dapB_mRNA
Description: Transcription of transcription unit dapB. Reaction activation by ArgP, and ArgP-arginine.
Type: transcription
Pathway Components: dapB - ArgP - ArgP-arginine -> dapB_mRNA
Components:
Function Name Type Evidence Reference(s)
activator ArgP protein nd nd
activator ArgP-arginine complex nd nd
reactant dapB gene nd nd
product dapB_mRNA RNA nd nd
ArgP ArgP-arginine dnaAN-recF dnaAN-recF_mRNA
Name: dnaAN-recF -> dnaAN-recF_mRNA
Description: Transcription of transcription unit dnaAN-recF. Reaction activation by ArgP, and ArgP-arginine.
Type: transcription
Pathway Components: dnaAN-recF - ArgP - ArgP-arginine -> dnaAN-recF_mRNA
Components:
Function Name Type Evidence Reference(s)
activator ArgP protein nd nd
activator ArgP-arginine complex nd nd
reactant dnaAN-recF gene nd nd
product dnaAN-recF_mRNA RNA nd nd
ArgP ArgP-arginine gdhA gdhA_mRNA
Name: gdhA -> gdhA_mRNA
Description: Transcription of transcription unit gdhA. Reaction activation by ArgP, and ArgP-arginine.
Type: transcription
Pathway Components: gdhA - ArgP - ArgP-arginine -> gdhA_mRNA
Components:
Function Name Type Evidence Reference(s)
activator ArgP protein nd nd
activator ArgP-arginine complex nd nd
reactant gdhA gene nd nd
product gdhA_mRNA RNA nd nd
ArgP ArgP-arginine lysA lysA_mRNA
Name: lysA -> lysA_mRNA
Description: Transcription of transcription unit lysA. Reaction activation by ArgP, and ArgP-arginine.
Type: transcription
Pathway Components: lysA - ArgP - ArgP-arginine -> lysA_mRNA
Components:
Function Name Type Evidence Reference(s)
activator ArgP protein nd nd
activator ArgP-arginine complex nd nd
reactant lysA gene nd nd
product lysA_mRNA RNA nd nd
ArgP ArgP-arginine lysC lysC_mRNA
Name: lysC -> lysC_mRNA
Description: Transcription of transcription unit lysC. Reaction activation by ArgP, and ArgP-arginine.
Type: transcription
Pathway Components: lysC - ArgP - ArgP-arginine -> lysC_mRNA
Components:
Function Name Type Evidence Reference(s)
activator ArgP protein nd nd
activator ArgP-arginine complex nd nd
reactant lysC gene nd nd
product lysC_mRNA RNA nd nd
ArgP ArgP-arginine lysP lysP_mRNA
Name: lysP -> lysP_mRNA
Description: Transcription of transcription unit lysP. Reaction activation by ArgP, and ArgP-arginine.
Type: transcription
Pathway Components: lysP - ArgP - ArgP-arginine -> lysP_mRNA
Components:
Function Name Type Evidence Reference(s)
activator ArgP protein nd nd
activator ArgP-arginine complex nd nd
reactant lysP gene nd nd
product lysP_mRNA RNA nd nd
ArgP ArgP-arginine map-glnD-dapD map-glnD-dapD_mRNA
Name: map-glnD-dapD -> map-glnD-dapD_mRNA
Description: Transcription of transcription unit map-glnD-dapD. Reaction activation by ArgP, and ArgP-arginine.
Type: transcription
Pathway Components: map-glnD-dapD - ArgP - ArgP-arginine -> map-glnD-dapD_mRNA
Components:
Function Name Type Evidence Reference(s)
activator ArgP protein nd nd
activator ArgP-arginine complex nd nd
reactant map-glnD-dapD gene nd nd
product map-glnD-dapD_mRNA RNA nd nd
ArgP ArgP-arginine nrdAB-yfaE nrdAB-yfaE_mRNA
Name: nrdAB-yfaE -> nrdAB-yfaE_mRNA
Description: Transcription of transcription unit nrdAB-yfaE. Reaction activation by ArgP, and ArgP-arginine.
Type: transcription
Pathway Components: nrdAB-yfaE - ArgP - ArgP-arginine -> nrdAB-yfaE_mRNA
Components:
Function Name Type Evidence Reference(s)
activator ArgP protein nd nd
activator ArgP-arginine complex nd nd
reactant nrdAB-yfaE gene nd nd
product nrdAB-yfaE_mRNA RNA nd nd
ArgP ArgP-arginine argP argP_mRNA
Name: argP -> argP_mRNA
Description: Transcription of transcription unit argP. Reaction inhibition by ArgP, and ArgP-arginine.
Type: transcription
Pathway Components: argP - ArgP - ArgP-arginine -> argP_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor ArgP protein nd nd
inhibitor ArgP-arginine complex nd nd
reactant argP gene nd nd
product argP_mRNA RNA nd nd
arginine + ArgP ArgP-arginine
Name: arginine + ArgP -> ArgP-arginine
Description: Reaction transforming arginine, ArgP into ArgP-arginine
Type: state transition
Pathway Components: arginine + ArgP -> ArgP-arginine
Components:
Function Name Type Evidence Reference(s)
reactant ArgP protein nd nd
product ArgP-arginine complex nd nd
reactant arginine simple_molecule nd nd
lysine + ArgP ArgP-lysine
Name: lysine + ArgP -> ArgP-lysine
Description: Reaction transforming lysine, ArgP into ArgP-lysine
Type: state transition
Pathway Components: lysine + ArgP -> ArgP-lysine
Components:
Function Name Type Evidence Reference(s)
reactant ArgP protein nd nd
product ArgP-lysine complex nd nd
reactant lysine simple_molecule nd nd
ArgP dapD dapD_mRNA
Name: dapD -> dapD_mRNA
Description: Transcription of transcription unit dapD. Reaction activation by ArgP.
Type: transcription
Pathway Components: dapD - ArgP -> dapD_mRNA
Components:
Function Name Type Evidence Reference(s)
activator ArgP protein nd nd
reactant dapD gene nd nd
product dapD_mRNA RNA nd nd
lysA_mRNA LysA
Name: lysA_mRNA -> LysA
Description: Translation of LysA
Type: translation
Pathway Components: lysA_mRNA -> LysA
Components:
Function Name Type Evidence Reference(s)
product LysA protein nd nd
reactant lysA_mRNA RNA nd nd
L-glutamate LysA lysine M-DAP lysine + CO2
Name: M-DAP -> lysine + CO2
Description: Reaction transforming M-DAP into lysine, CO2
Type: state transition
Pathway Components: M-DAP - LysA - L-glutamate - lysine -> lysine + CO2
Components:
Function Name Type Evidence Reference(s)
product CO2 simple_molecule nd nd
inhibitor L-glutamate simple_molecule nd nd
catalyzer LysA protein nd nd
reactant M-DAP simple_molecule nd nd
inhibitor lysine simple_molecule nd nd
product lysine simple_molecule nd nd
argO_mRNA ArgO
Name: argO_mRNA -> ArgO
Description: Translation of ArgO
Type: translation
Pathway Components: argO_mRNA -> ArgO
Components:
Function Name Type Evidence Reference(s)
product ArgO protein nd nd
reactant argO_mRNA RNA nd nd
ArgO arginine_Ext arginine
Name: arginine_Ext -> arginine
Description: Transport of arginine_Ext through a bacterial membrane, leading to the presence of arginine inside the cell.
Type: transport
Pathway Components: arginine_Ext - ArgO -> arginine
Components:
Function Name Type Evidence Reference(s)
catalyzer ArgO protein nd nd
product arginine simple_molecule nd nd
reactant arginine_Ext simple_molecule nd nd
gdhA_mRNA GdhA
Name: gdhA_mRNA -> GdhA
Description: Translation of GdhA
Type: translation
Pathway Components: gdhA_mRNA -> GdhA
Components:
Function Name Type Evidence Reference(s)
product GdhA protein nd nd
reactant gdhA_mRNA RNA nd nd
GdhA L-glutamate ketoglutarate + ammonium
Name: L-glutamate -> ketoglutarate + ammonium
Description: Reaction transforming L-glutamate into ketoglutarate, ammonium
Type: state transition
Pathway Components: L-glutamate - GdhA -> ketoglutarate + ammonium
Components:
Function Name Type Evidence Reference(s)
catalyzer GdhA protein nd nd
reactant L-glutamate simple_molecule nd nd
product ammonium simple_molecule nd nd
product ketoglutarate simple_molecule nd nd
lysC_mRNA LysC
Name: lysC_mRNA -> LysC
Description: Translation of LysC
Type: translation
Pathway Components: lysC_mRNA -> LysC
Components:
Function Name Type Evidence Reference(s)
product LysC protein nd nd
reactant lysC_mRNA RNA nd nd
LysC lysine aspartate aspartyl-4-P
Name: aspartate -> aspartyl-4-P
Description: Reaction transforming aspartate into aspartyl-4-P
Type: state transition
Pathway Components: aspartate - LysC - lysine -> aspartyl-4-P
Components:
Function Name Type Evidence Reference(s)
catalyzer LysC protein nd nd
reactant aspartate simple_molecule nd nd
product aspartyl-4-P simple_molecule nd nd
inhibitor lysine simple_molecule nd nd
dapD_mRNA DapD
Name: dapD_mRNA -> DapD
Description: Translation of DapD
Type: translation
Pathway Components: dapD_mRNA -> DapD
Components:
Function Name Type Evidence Reference(s)
product DapD protein nd nd
reactant dapD_mRNA RNA nd nd
DapD tetrahydrodipicolinate + suc-coa Products
Name: tetrahydrodipicolinate + suc-coa -> N-Succinyl-2-L-amino-6-oxoheptanedioate + coenzyme A
Description: Reaction transforming tetrahydrodipicolinate, suc-coa into N-Succinyl-2-L-amino-6-oxoheptanedioate, coenzyme A
Type: state transition
Pathway Components: tetrahydrodipicolinate + suc-coa - DapD -> N-Succinyl-2-L-amino-6-oxoheptanedioate + coenzyme A
Components:
Function Name Type Evidence Reference(s)
catalyzer DapD protein nd nd
product N-Succinyl-2-L-amino-6-oxoheptanedioate simple_molecule nd nd
product coenzyme A simple_molecule nd nd
reactant suc-coa simple_molecule nd nd
reactant tetrahydrodipicolinate simple_molecule nd nd
lysP_mRNA LysP
Name: lysP_mRNA -> LysP
Description: Translation of LysP
Type: translation
Pathway Components: lysP_mRNA -> LysP
Components:
Function Name Type Evidence Reference(s)
product LysP protein nd nd
reactant lysP_mRNA RNA nd nd
LysP lysine_Ext lysine
Name: lysine_Ext -> lysine
Description: Transport of lysine_Ext through a bacterial membrane, leading to the presence of lysine inside the cell.
Type: transport
Pathway Components: lysine_Ext - LysP -> lysine
Components:
Function Name Type Evidence Reference(s)
catalyzer LysP protein nd nd
product lysine simple_molecule nd nd
reactant lysine_Ext simple_molecule nd nd
nrdAB-yfaE_mRNA NrdA
Name: nrdAB-yfaE_mRNA -> NrdA
Description: Translation of NrdA
Type: translation
Pathway Components: nrdAB-yfaE_mRNA -> NrdA
Components:
Function Name Type Evidence Reference(s)
product NrdA protein nd nd
reactant nrdAB-yfaE_mRNA RNA nd nd
NrdB + NrdA NrdA-NrdB
Name: NrdB + NrdA -> NrdA-NrdB
Description: Reaction transforming NrdB, NrdA into NrdA-NrdB
Type: state transition
Pathway Components: NrdB + NrdA -> NrdA-NrdB
Components:
Function Name Type Evidence Reference(s)
reactant NrdA protein nd nd
product NrdA-NrdB complex nd nd
reactant NrdB protein nd nd
NrdA-NrdB dCDP nucleoside diphosphate + reduced thioredoxin Products
Name: nucleoside diphosphate + reduced thioredoxin -> deoxynucleoside diphosphate + thioredoxin disulfide
Description: Reaction transforming nucleoside diphosphate, reduced thioredoxin into deoxynucleoside diphosphate, thioredoxin disulfide
Type: state transition
Pathway Components: nucleoside diphosphate + reduced thioredoxin - NrdA-NrdB - dCDP -> deoxynucleoside diphosphate + thioredoxin disulfide
Components:
Function Name Type Evidence Reference(s)
catalyzer NrdA-NrdB complex nd nd
inhibitor dCDP simple_molecule nd nd
product deoxynucleoside diphosphate simple_molecule nd nd
reactant nucleoside diphosphate simple_molecule nd nd
reactant reduced thioredoxin simple_molecule nd nd
product thioredoxin disulfide simple_molecule nd nd
NrdA-NrdB cytidine-diphosphate + reduced thioredoxin thioredoxin disulfide + dCDP
Name: cytidine-diphosphate + reduced thioredoxin -> thioredoxin disulfide + dCDP
Description: Reaction transforming cytidine-diphosphate, reduced thioredoxin into thioredoxin disulfide, dCDP
Type: state transition
Pathway Components: cytidine-diphosphate + reduced thioredoxin - NrdA-NrdB -> thioredoxin disulfide + dCDP
Components:
Function Name Type Evidence Reference(s)
catalyzer NrdA-NrdB complex nd nd
reactant cytidine-diphosphate simple_molecule nd nd
product dCDP simple_molecule nd nd
reactant reduced thioredoxin simple_molecule nd nd
product thioredoxin disulfide simple_molecule nd nd
NrdA-NrdB reduced thioredoxin + uridine-diphosphate thioredoxin disulfide + dUDP
Name: reduced thioredoxin + uridine-diphosphate -> thioredoxin disulfide + dUDP
Description: Reaction transforming reduced thioredoxin, uridine-diphosphate into thioredoxin disulfide, dUDP
Type: state transition
Pathway Components: reduced thioredoxin + uridine-diphosphate - NrdA-NrdB -> thioredoxin disulfide + dUDP
Components:
Function Name Type Evidence Reference(s)
catalyzer NrdA-NrdB complex nd nd
product dUDP simple_molecule nd nd
reactant reduced thioredoxin simple_molecule nd nd
product thioredoxin disulfide simple_molecule nd nd
reactant uridine-diphosphate simple_molecule nd nd
NrdA-NrdB thioredoxin disulfide + dADP reduced thioredoxin
Name: thioredoxin disulfide + dADP -> reduced thioredoxin
Description: Reaction transforming thioredoxin disulfide, dADP into reduced thioredoxin
Type: state transition
Pathway Components: thioredoxin disulfide + dADP - NrdA-NrdB -> reduced thioredoxin
Components:
Function Name Type Evidence Reference(s)
catalyzer NrdA-NrdB complex nd nd
reactant dADP simple_molecule nd nd
product reduced thioredoxin simple_molecule nd nd
reactant thioredoxin disulfide simple_molecule nd nd
NrdA-NrdB guanosine-diphosphate + reduced thioredoxin thioredoxin disulfide + dGDP
Name: guanosine-diphosphate + reduced thioredoxin -> thioredoxin disulfide + dGDP
Description: Reaction transforming guanosine-diphosphate, reduced thioredoxin into thioredoxin disulfide, dGDP
Type: state transition
Pathway Components: guanosine-diphosphate + reduced thioredoxin - NrdA-NrdB -> thioredoxin disulfide + dGDP
Components:
Function Name Type Evidence Reference(s)
catalyzer NrdA-NrdB complex nd nd
product dGDP simple_molecule nd nd
reactant guanosine-diphosphate simple_molecule nd nd
reactant reduced thioredoxin simple_molecule nd nd
product thioredoxin disulfide simple_molecule nd nd
nrdAB-yfaE_mRNA NrdB
Name: nrdAB-yfaE_mRNA -> NrdB
Description: Translation of NrdB
Type: translation
Pathway Components: nrdAB-yfaE_mRNA -> NrdB
Components:
Function Name Type Evidence Reference(s)
product NrdB protein nd nd
reactant nrdAB-yfaE_mRNA RNA nd nd
nrdAB-yfaE_mRNA YfaE
Name: nrdAB-yfaE_mRNA -> YfaE
Description: Translation of YfaE
Type: translation
Pathway Components: nrdAB-yfaE_mRNA -> YfaE
Components:
Function Name Type Evidence Reference(s)
product YfaE protein nd nd
reactant nrdAB-yfaE_mRNA RNA nd nd
map-glnD-dapD_mRNA DapD
Name: map-glnD-dapD_mRNA -> DapD
Description: Translation of DapD
Type: translation
Pathway Components: map-glnD-dapD_mRNA -> DapD
Components:
Function Name Type Evidence Reference(s)
product DapD protein nd nd
reactant map-glnD-dapD_mRNA RNA nd nd
map-glnD-dapD_mRNA GlnD
Name: map-glnD-dapD_mRNA -> GlnD
Description: Translation of GlnD
Type: translation
Pathway Components: map-glnD-dapD_mRNA -> GlnD
Components:
Function Name Type Evidence Reference(s)
product GlnD protein nd nd
reactant map-glnD-dapD_mRNA RNA nd nd
GlnD uridine-triphosphate + GlnB diphosphate + GlnB
Name: uridine-triphosphate + GlnB -> diphosphate + GlnB
Description: Reaction transforming uridine-triphosphate, GlnB into diphosphate, GlnB
Type: state transition
Pathway Components: uridine-triphosphate + GlnB - GlnD -> diphosphate + GlnB
Components:
Function Name Type Evidence Reference(s)
product GlnB simple_molecule nd nd
reactant GlnB simple_molecule nd nd
catalyzer GlnD protein nd nd
product diphosphate simple_molecule nd nd
reactant uridine-triphosphate simple_molecule nd nd
GlnD GlnB 5'-UMP + GlnB
Name: GlnB -> 5'-UMP + GlnB
Description: Reaction transforming GlnB into 5'-UMP, GlnB
Type: state transition
Pathway Components: GlnB - GlnD -> 5'-UMP + GlnB
Components:
Function Name Type Evidence Reference(s)
product 5'-UMP simple_molecule nd nd
product GlnB simple_molecule nd nd
reactant GlnB simple_molecule nd nd
catalyzer GlnD protein nd nd
GlnD uridine-triphosphate + GlnK diphosphate + YbaI
Name: uridine-triphosphate + GlnK -> diphosphate + YbaI
Description: Reaction transforming uridine-triphosphate, GlnK into diphosphate, YbaI
Type: state transition
Pathway Components: uridine-triphosphate + GlnK - GlnD -> diphosphate + YbaI
Components:
Function Name Type Evidence Reference(s)
catalyzer GlnD protein nd nd
reactant GlnK simple_molecule nd nd
product YbaI simple_molecule nd nd
product diphosphate simple_molecule nd nd
reactant uridine-triphosphate simple_molecule nd nd
map-glnD-dapD_mRNA Map
Name: map-glnD-dapD_mRNA -> Map
Description: Translation of Map
Type: translation
Pathway Components: map-glnD-dapD_mRNA -> Map
Components:
Function Name Type Evidence Reference(s)
product Map protein nd nd
reactant map-glnD-dapD_mRNA RNA nd nd
Map peptide with an N-terminal L-methionine methionine + peptide
Name: peptide with an N-terminal L-methionine -> methionine + peptide
Description: Reaction transforming peptide with an N-terminal L-methionine into methionine, peptide
Type: state transition
Pathway Components: peptide with an N-terminal L-methionine - Map -> methionine + peptide
Components:
Function Name Type Evidence Reference(s)
catalyzer Map protein nd nd
product methionine simple_molecule nd nd
product peptide simple_molecule nd nd
reactant peptide with an N-terminal L-methionine simple_molecule nd nd
argP_mRNA ArgP
Name: argP_mRNA -> ArgP
Description: Translation of ArgP
Type: translation
Pathway Components: argP_mRNA -> ArgP
Components:
Function Name Type Evidence Reference(s)
product ArgP protein nd nd
reactant argP_mRNA RNA nd nd
dnaAN-recF_mRNA DnaA
Name: dnaAN-recF_mRNA -> DnaA
Description: Translation of DnaA
Type: translation
Pathway Components: dnaAN-recF_mRNA -> DnaA
Components:
Function Name Type Evidence Reference(s)
product DnaA protein nd nd
reactant dnaAN-recF_mRNA RNA nd nd
dnaAN-recF_mRNA DnaN
Name: dnaAN-recF_mRNA -> DnaN
Description: Translation of DnaN
Type: translation
Pathway Components: dnaAN-recF_mRNA -> DnaN
Components:
Function Name Type Evidence Reference(s)
product DnaN protein nd nd
reactant dnaAN-recF_mRNA RNA nd nd
Protein Monomers HolE-DnaQ-DnaE-HolA-HolB-DnaX-DnaN-HolD-HolC
Name: HolE + HolA + DnaN + HolB + HolC + HolD + DnaE + DnaX + DnaQ -> HolE-DnaQ-DnaE-HolA-HolB-DnaX-DnaN-HolD-HolC
Description: Reaction transforming HolE, HolA, DnaN, HolB, HolC, HolD, DnaE, DnaX, DnaQ into HolE-DnaQ-DnaE-HolA-HolB-DnaX-DnaN-HolD-HolC
Type: state transition
Pathway Components: HolE + HolA + DnaN + HolB + HolC + HolD + DnaE + DnaX + DnaQ -> HolE-DnaQ-DnaE-HolA-HolB-DnaX-DnaN-HolD-HolC
Components: Show/Hide Components Table
dnaAN-recF_mRNA RecF
Name: dnaAN-recF_mRNA -> RecF
Description: Translation of RecF
Type: translation
Pathway Components: dnaAN-recF_mRNA -> RecF
Components:
Function Name Type Evidence Reference(s)
product RecF protein nd nd
reactant dnaAN-recF_mRNA RNA nd nd
RecO + RecF + RecR RecF-RecR-RecO
Name: RecO + RecF + RecR -> RecF-RecR-RecO
Description: Reaction transforming RecO, RecF, RecR into RecF-RecR-RecO
Type: state transition
Pathway Components: RecO + RecF + RecR -> RecF-RecR-RecO
Components:
Function Name Type Evidence Reference(s)
reactant RecF protein nd nd
product RecF-RecR-RecO complex nd nd
reactant RecO protein nd nd
reactant RecR protein nd nd
RecF-RecR-RecO unstable RecA filament-DNA complex stabilized RecA filament-DNA complex
Name: unstable RecA filament-DNA complex -> stabilized RecA filament-DNA complex
Description: Reaction transforming unstable RecA filament-DNA complex into stabilized RecA filament-DNA complex
Type: state transition
Pathway Components: unstable RecA filament-DNA complex - RecF-RecR-RecO -> stabilized RecA filament-DNA complex
Components:
Function Name Type Evidence Reference(s)
catalyzer RecF-RecR-RecO complex nd nd
product stabilized RecA filament-DNA complex simple_molecule nd nd
reactant unstable RecA filament-DNA complex simple_molecule nd nd
dapB_mRNA DapB
Name: dapB_mRNA -> DapB
Description: Translation of DapB
Type: translation
Pathway Components: dapB_mRNA -> DapB
Components:
Function Name Type Evidence Reference(s)
product DapB protein nd nd
reactant dapB_mRNA RNA nd nd
DapB (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate tetrahydrodipicolinate
Name: (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate -> tetrahydrodipicolinate
Description: Reaction transforming (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate into tetrahydrodipicolinate
Type: state transition
Pathway Components: (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate - DapB -> tetrahydrodipicolinate
Components:
Function Name Type Evidence Reference(s)
reactant (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate simple_molecule nd nd
catalyzer DapB protein nd nd
product tetrahydrodipicolinate simple_molecule nd nd
N-Succinyl-2-L-amino-6-oxoheptanedioate M-DAP
Name: N-Succinyl-2-L-amino-6-oxoheptanedioate -> M-DAP
Description: Transformation of N-Succinyl-2-L-amino-6-oxoheptanedioate into M-DAP by one or more reactions not shown.
Type: complementary pathway reaction
Pathway Components: N-Succinyl-2-L-amino-6-oxoheptanedioate / SUCCINYLDIAMINOPIMTRANS-RXN / SUCCDIAMINOPIMDESUCC-RXN / DIAMINOPIMEPIM-RXN / M-DAP
Components:
Function Name Type Evidence Reference(s)
product M-DAP simple_molecule nd nd
reactant N-Succinyl-2-L-amino-6-oxoheptanedioate simple_molecule nd nd
aspartyl-4-P (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate
Name: aspartyl-4-P -> (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate
Description: Transformation of aspartyl-4-P into (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate by one or more reactions not shown.
Type: complementary pathway reaction
Pathway Components: aspartyl-4-P / ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN / DIHYDRODIPICSYN-RXN / (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate
Components:
Function Name Type Evidence Reference(s)
product (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate simple_molecule nd nd
reactant aspartyl-4-P simple_molecule nd nd



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