RegulonDB RegulonDB

ArgP Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate tetrahydrodipicolinate ketoglutarate ArgO ArgP CDP CO2 DapB DapD DnaA DnaN GDP GdhA L-arginine asp L-aspartyl-4-P L-glutamate L-lysine L-lysine_Ext LysA LysC LysP N-Succinyl-2-L-amino-6-oxoheptanedioate NrdA NrdB RecF RecO RecR Udp YfaE a 2'-deoxyribonucleoside 5'-diphosphate a reduced thioredoxin nucleoside diphosphate a stabilized RecA filament-DNA complex ammonia oxidized thioredoxin an unstable RecA filament-DNA complex argO argO_mRNA argP argP_mRNA CoA dADP dCDP dGDP dUDP dapB dapB_mRNA dapD dapD_mRNA dnaAN-recF dnaAN-recF_mRNA gdhA gdhA_mRNA lysA lysA_mRNA lysC lysC_mRNA lysP lysP_mRNA M-DAP nrdAB-yfaE nrdAB-yfaE_mRNA suc-coa ArgP L-arginine ArgP L-lysine RecF RecR RecO NrdA NrdB oxidized thioredoxin a reduced thioredoxin a reduced thioredoxin oxidized thioredoxin dUTP


Gensor Unit       
Name: ArgP
Classification:
Groups: GUs related to the metabolism of amino acids
Gene Ontology Terms (GO): GO:0019877 - diaminopimelate biosynthetic process
GO:0003688 - DNA replication origin binding
GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0004354 - glutamate dehydrogenase (NADP+) activity
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0045892 - negative regulation of transcription, DNA-templated
GO:0016491 - oxidoreductase activity
GO:0016020 - membrane
GO:0008652 - cellular amino acid biosynthetic process
GO:0003824 - catalytic activity
GO:0051287 - NAD binding
Read more >
Components:
Function Name Type
simple molecule dUTP simple molecule


Reactions       
Showing 43 reactions
dapB dapB_mRNA
Name: dapB -> dapB_mRNA
Description: Transcription of transcription unit dapB; reaction activation by ArgP.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant dapB gene nd nd
product dapB_mRNA RNA nd nd
dapD dapD_mRNA
Name: dapD -> dapD_mRNA
Description: Transcription of transcription unit dapD; reaction activation by ArgP.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product dapD_mRNA RNA nd nd
reactant dapD gene nd nd
dnaAN-recF dnaAN-recF_mRNA
Name: dnaAN-recF -> dnaAN-recF_mRNA
Description: Transcription of transcription unit dnaAN-recF; reaction activation by ArgP.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product dnaAN-recF_mRNA RNA nd nd
reactant dnaAN-recF gene nd nd
gdhA gdhA_mRNA
Name: gdhA -> gdhA_mRNA
Description: Transcription of transcription unit gdhA; reaction activation by ArgP.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant gdhA gene nd nd
product gdhA_mRNA RNA nd nd
lysA lysA_mRNA
Name: lysA -> lysA_mRNA
Description: Transcription of transcription unit lysA; reaction activation by ArgP.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product lysA_mRNA RNA nd nd
reactant lysA gene nd nd
lysC lysC_mRNA
Name: lysC -> lysC_mRNA
Description: Transcription of transcription unit lysC; reaction activation by ArgP.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product lysC_mRNA RNA nd nd
reactant lysC gene nd nd
lysP lysP_mRNA
Name: lysP -> lysP_mRNA
Description: Transcription of transcription unit lysP; reaction activation by ArgP.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product lysP_mRNA RNA nd nd
reactant lysP gene nd nd
nrdAB-yfaE nrdAB-yfaE_mRNA
Name: nrdAB-yfaE -> nrdAB-yfaE_mRNA
Description: Transcription of transcription unit nrdAB-yfaE; reaction activation by ArgP.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product nrdAB-yfaE_mRNA RNA nd nd
reactant nrdAB-yfaE gene nd nd
ArgP + L-arginine ArgP-L-arginine
Name: ArgP + L-arginine -> ArgP-L-arginine
Description: Reaction transforming ArgP, L-arginine into ArgP-L-arginine
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant ArgP protein nd nd
reactant L-arginine simple molecule nd nd
product ArgP-L-arginine complex nd nd
argO argO_mRNA
Name: argO -> argO_mRNA
Description: Transcription of transcription unit argO; reaction activation by ArgP-L-arginine.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product argO_mRNA RNA nd nd
reactant argO gene nd nd
argP argP_mRNA
Name: argP -> argP_mRNA
Description: Transcription of transcription unit argP; reaction inhibition by ArgP-L-arginine.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product argP_mRNA RNA nd nd
reactant argP gene nd nd
ArgP + L-lysine ArgP-L-lysine
Name: ArgP + L-lysine -> ArgP-L-lysine
Description: Reaction transforming ArgP, L-lysine into ArgP-L-lysine
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant L-lysine simple molecule nd nd
product ArgP-L-lysine complex nd nd
reactant ArgP protein nd nd
dnaAN-recF_mRNA RecF
Name: dnaAN-recF_mRNA -> RecF
Description: Translation of RecF
Type: translation
Components:
Function Name Type Evidence Reference(s)
product RecF protein nd nd
reactant dnaAN-recF_mRNA RNA nd nd
RecF + RecR + RecO RecF-RecR-RecO
Name: RecF + RecR + RecO -> RecF-RecR-RecO
Description: Reaction transforming RecF, RecR, RecO into RecF-RecR-RecO
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant RecR protein nd nd
reactant RecF protein nd nd
product RecF-RecR-RecO complex nd nd
reactant RecO protein nd nd
an unstable RecA filament-DNA complex a stabilized RecA filament-DNA complex
Name: an unstable RecA filament-DNA complex -> a stabilized RecA filament-DNA complex
Description: Reaction transforming an unstable RecA filament-DNA complex into a stabilized RecA filament-DNA complex
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product a stabilized RecA filament-DNA complex simple molecule nd nd
reactant an unstable RecA filament-DNA complex simple molecule nd nd
lysA_mRNA LysA
Name: lysA_mRNA -> LysA
Description: Translation of LysA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant lysA_mRNA RNA nd nd
product LysA protein nd nd
M-DAP L-lysine + CO2
Name: M-DAP -> L-lysine + CO2
Description: Reaction transforming M-DAP into L-lysine, CO2
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product L-lysine simple molecule nd nd
reactant M-DAP simple molecule nd nd
product CO2 simple molecule nd nd
argO_mRNA ArgO
Name: argO_mRNA -> ArgO
Description: Translation of ArgO
Type: translation
Components:
Function Name Type Evidence Reference(s)
product ArgO protein nd nd
reactant argO_mRNA RNA nd nd
dnaAN-recF_mRNA DnaA
Name: dnaAN-recF_mRNA -> DnaA
Description: Translation of DnaA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant dnaAN-recF_mRNA RNA nd nd
product DnaA protein nd nd
nrdAB-yfaE_mRNA YfaE
Name: nrdAB-yfaE_mRNA -> YfaE
Description: Translation of YfaE
Type: translation
Components:
Function Name Type Evidence Reference(s)
product YfaE protein nd nd
reactant nrdAB-yfaE_mRNA RNA nd nd
gdhA_mRNA GdhA
Name: gdhA_mRNA -> GdhA
Description: Translation of GdhA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product GdhA protein nd nd
reactant gdhA_mRNA RNA nd nd
L-glutamate ketoglutarate + ammonia
Name: L-glutamate -> ketoglutarate + ammonia
Description: Reaction transforming L-glutamate into ketoglutarate, ammonia
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant L-glutamate simple molecule nd nd
product ketoglutarate simple molecule nd nd
product ammonia simple molecule nd nd
dnaAN-recF_mRNA DnaN
Name: dnaAN-recF_mRNA -> DnaN
Description: Translation of DnaN
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant dnaAN-recF_mRNA RNA nd nd
product DnaN protein nd nd
lysC_mRNA LysC
Name: lysC_mRNA -> LysC
Description: Translation of LysC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product LysC protein nd nd
reactant lysC_mRNA RNA nd nd
asp L-aspartyl-4-P
Name: asp -> L-aspartyl-4-P
Description: Reaction transforming asp into L-aspartyl-4-P
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product L-aspartyl-4-P simple molecule nd nd
reactant asp simple molecule nd nd
dapD_mRNA DapD
Name: dapD_mRNA -> DapD
Description: Translation of DapD
Type: translation
Components:
Function Name Type Evidence Reference(s)
product DapD protein nd nd
reactant dapD_mRNA RNA nd nd
tetrahydrodipicolinate + suc-coa N-Succinyl-2-L-amino-6-oxoheptanedioate + CoA
Name: tetrahydrodipicolinate + suc-coa -> N-Succinyl-2-L-amino-6-oxoheptanedioate + CoA
Description: Reaction transforming tetrahydrodipicolinate, suc-coa into N-Succinyl-2-L-amino-6-oxoheptanedioate, CoA
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product N-Succinyl-2-L-amino-6-oxoheptanedioate simple molecule nd nd
product CoA simple molecule nd nd
reactant suc-coa simple molecule nd nd
reactant tetrahydrodipicolinate simple molecule nd nd
lysP_mRNA LysP
Name: lysP_mRNA -> LysP
Description: Translation of LysP
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant lysP_mRNA RNA nd nd
product LysP protein nd nd
L-lysine_Ext L-lysine
Name: L-lysine_Ext -> L-lysine
Description: Transport of L-lysine_Ext through a bacterial membrane, leading to the presence of L-lysine inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product L-lysine simple molecule nd nd
reactant L-lysine_Ext simple molecule nd nd
nrdAB-yfaE_mRNA NrdA
Name: nrdAB-yfaE_mRNA -> NrdA
Description: Translation of NrdA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product NrdA protein nd nd
reactant nrdAB-yfaE_mRNA RNA nd nd
NrdA + NrdB NrdA-NrdB
Name: NrdA + NrdB -> NrdA-NrdB
Description: Reaction transforming NrdA, NrdB into NrdA-NrdB
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant NrdB protein nd nd
reactant NrdA protein nd nd
product NrdA-NrdB complex nd nd
oxidized thioredoxin + deoxynucleoside diphosphate reduced thioredoxin + nucleoside diphosphate
Name: oxidized thioredoxin + deoxynucleoside diphosphate -> reduced thioredoxin + nucleoside diphosphate
Description: Reaction transforming oxidized thioredoxin, deoxynucleoside diphosphate into reduced thioredoxin, nucleoside diphosphate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant oxidized thioredoxin simple molecule nd nd
product reduced thioredoxin simple molecule nd nd
product nucleoside diphosphate simple molecule nd nd
reactant deoxynucleoside diphosphate simple molecule nd nd
dCDP + oxidized thioredoxin CDP + reduced thioredoxin
Name: dCDP + oxidized thioredoxin -> CDP + reduced thioredoxin
Description: Reaction transforming dCDP, oxidized thioredoxin into CDP, reduced thioredoxin
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant dCDP simple molecule nd nd
reactant oxidized thioredoxin simple molecule nd nd
product reduced thioredoxin simple molecule nd nd
product CDP simple molecule nd nd
dUDP + oxidized thioredoxin UDP + reduced thioredoxin
Name: dUDP + oxidized thioredoxin -> UDP + reduced thioredoxin
Description: Reaction transforming dUDP, oxidized thioredoxin into UDP, reduced thioredoxin
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product reduced thioredoxin simple molecule nd nd
reactant dUDP simple molecule nd nd
reactant oxidized thioredoxin simple molecule nd nd
product UDP simple molecule nd nd
dADP + oxidized thioredoxin reduced thioredoxin
Name: dADP + oxidized thioredoxin -> reduced thioredoxin
Description: Reaction transforming dADP, oxidized thioredoxin into reduced thioredoxin
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant oxidized thioredoxin simple molecule nd nd
product reduced thioredoxin simple molecule nd nd
reactant dADP simple molecule nd nd
dGDP + oxidized thioredoxin GDP + reduced thioredoxin
Name: dGDP + oxidized thioredoxin -> GDP + reduced thioredoxin
Description: Reaction transforming dGDP, oxidized thioredoxin into GDP, reduced thioredoxin
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product GDP simple molecule nd nd
product reduced thioredoxin simple molecule nd nd
reactant dGDP simple molecule nd nd
reactant oxidized thioredoxin simple molecule nd nd
nrdAB-yfaE_mRNA NrdB
Name: nrdAB-yfaE_mRNA -> NrdB
Description: Translation of NrdB
Type: translation
Components:
Function Name Type Evidence Reference(s)
product NrdB protein nd nd
reactant nrdAB-yfaE_mRNA RNA nd nd
argP_mRNA ArgP
Name: argP_mRNA -> ArgP
Description: Translation of ArgP
Type: translation
Components:
Function Name Type Evidence Reference(s)
product ArgP protein nd nd
reactant argP_mRNA RNA nd nd
dapB_mRNA DapB
Name: dapB_mRNA -> DapB
Description: Translation of DapB
Type: translation
Components:
Function Name Type Evidence Reference(s)
product DapB protein nd nd
reactant dapB_mRNA RNA nd nd
tetrahydrodipicolinate (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate
Name: tetrahydrodipicolinate -> (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate
Description: Reaction transforming tetrahydrodipicolinate into (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant tetrahydrodipicolinate simple molecule nd nd
product (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate simple molecule nd nd
dUDP dUTP
Name: dUDP -> dUTP
Description: Transformation of dUDP into dUTP by one, or two/three reactions not shown.
Type: super-reaction
Components:
Function Name Type Evidence Reference(s)
product dUTP simple molecule nd nd
reactant dUDP simple molecule nd nd
dCDP dUTP
Name: dCDP -> dUTP
Description: Transformation of dCDP into dUTP by one, or two/three reactions not shown.
Type: super-reaction
Components:
Function Name Type Evidence Reference(s)
reactant dCDP simple molecule nd nd
product dUTP simple molecule nd nd
UDP CDP
Name: UDP -> CDP
Description: Transformation of UDP into CDP by one, or two/three reactions not shown.
Type: super-reaction
Components:
Function Name Type Evidence Reference(s)
reactant UDP simple molecule nd nd
product CDP simple molecule nd nd



RegulonDB