RegulonDB RegulonDB

ArgP Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
guanosine-diphosphate RecO GdhA NrdB canavanine dnaAN-recF_mRNA LysP CO2 DapD HolD RecF nrdAB-yfaE ArgP aspartate DnaE dapB_mRNA NrdA DnaQ lysine RecR argP lysine_Ext DnaQ dapD arginine YfaE HolB coenzyme A DnaX NrdA lysA argP_mRNA ammonium DnaE dUDP RecO ArgO nucleoside diphosphate HolA RecR DnaX DapB aspartyl-4-P uridine-diphosphate lysC LysA cytidine-diphosphate suc-coa dADP DnaN HolB unstable RecA filament-DNA complex dGDP gdhA_mRNA lysP_mRNA HolC stabilized RecA filament-DNA complex lysC_mRNA ArgP HolA dCDP ArgP N-Succinyl-2-L-amino-6-oxoheptanedioate HolD ketoglutarate DnaA HolE arginine gdhA tetrahydrodipicolinate dnaAN-recF argO_mRNA dapD_mRNA (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate nrdAB-yfaE_mRNA lysP M-DAP DnaN argO L-glutamate thioredoxin disulfide lysA_mRNA LysC canavanine_Ext HolC RecF lysine dapB HolE reduced thioredoxin NrdB deoxynucleoside diphosphate arginine_Ext reduced thioredoxin thioredoxin disulfide dCDP thioredoxin disulfide


Gensor Unit       
Name: ArgP
Description: Molecular biology level
Detailed: In the absence of L-lysine, ArgP positively regulates the expression of genes required for lysine and glutamate biosynthetic process, DNA replication and recombination, and deoxyribonucleoside metabolic process. Under these conditions, ArgP binds its target sites enabling the expression of its regulated genes. In the presence of L-lysine, ArgP is modified to ArgP-L-lysine, binds its own promoter, preventing its own expression.
Less detailed: In the absence of L-lysine, ArgP positively regulates the expression of genes needed for lysine and glutamate biosynthetic processes, DNA replication and recombination, and deoxyribonucleoside metabolic process.

Physiology level
Detailed: The presence of L-lysine inhibits the expression of genes involved with lysine and glutamate biosynthetic process, DNA replication and recombination, and deoxyribonucleoside metabolic process. Under these condition the genes necessary for biosynthesis of L-lysine from M-DAP and tetrahydropicolinate, conversion of ketoglutarate to L-glutamate, oxidation of nucleosides and DNA recombination are expressed.
Less detailed: The presence of L-lysine induces the expression of genes needful for biosynthesis of L-lysine from M-DAP and tetrahydropicolinate, conversion of ketoglutarate to L-glutamate, oxidation of nucleosides and DNA recombination.
Classification:
Groups: Transcription
Energy production and conversion
Replication, recombination and repair
Amino acid transport and metabolism
Nucleotide transport and metabolism
Gene Ontology Terms (GO): biological_process GO:0071897 - DNA biosynthetic process
GO:0006281 - DNA repair
GO:0006260 - DNA replication
GO:0006270 - DNA replication initiation
GO:0006271 - DNA strand elongation involved in DNA replication
GO:0000731 - DNA synthesis involved in DNA repair
Read more >
cellular_component GO:0009360 - DNA polymerase III complex
GO:0005737 - cytoplasm
GO:0009898 - cytoplasmic side of plasma membrane
GO:0005829 - cytosol
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0016020 - membrane
Read more >
molecular_function GO:0051537 - 2 iron, 2 sulfur cluster binding
GO:0008666 - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity
GO:0008408 - 3'-5' exonuclease activity
GO:0008839 - 4-hydroxy-tetrahydrodipicolinate reductase
GO:0005524 - ATP binding
GO:0003677 - DNA binding
GO:0003688 - DNA replication origin binding
Read more >
Components:
  Function Name Type
  simple_molecule (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate simple_molecule
  protein ArgO protein
  protein ArgP protein
  complex ArgP-arginine complex
  complex ArgP-lysine complex
  simple_molecule CO2 simple_molecule
  protein DapB protein
  protein DapD protein
  protein DnaA protein
  protein DnaE protein
  protein DnaN protein
  protein DnaQ protein
  protein DnaX protein
  protein GdhA protein
  protein HolA protein
  protein HolB protein
  protein HolC protein
  protein HolD protein
  protein HolE protein
  complex HolE-DnaQ-DnaE-HolA-HolB-DnaX-DnaN-HolD-HolC complex
  simple_molecule L-glutamate simple_molecule
  protein LysA protein
  protein LysC protein
  protein LysP protein
  simple_molecule M-DAP simple_molecule
  simple_molecule N-Succinyl-2-L-amino-6-oxoheptanedioate simple_molecule
  protein NrdA protein
  complex NrdA-NrdB complex
  protein NrdB protein
  protein RecF protein
  complex RecF-RecR-RecO complex
  protein RecO protein
  protein RecR protein
  protein YfaE protein
  simple_molecule ammonium simple_molecule
  gene argO gene
  RNA argO_mRNA RNA
  gene argP gene
  RNA argP_mRNA RNA
  simple_molecule arginine simple_molecule
  simple_molecule arginine_Ext simple_molecule
  simple_molecule aspartate simple_molecule
  simple_molecule aspartyl-4-P simple_molecule
  simple_molecule canavanine simple_molecule
  simple_molecule canavanine_Ext simple_molecule
  simple_molecule coenzyme A simple_molecule
  simple_molecule cytidine-diphosphate simple_molecule
  simple_molecule dADP simple_molecule
  simple_molecule dCDP simple_molecule
  simple_molecule dGDP simple_molecule
  simple_molecule dUDP simple_molecule
  gene dapB gene
  RNA dapB_mRNA RNA
  gene dapD gene
  RNA dapD_mRNA RNA
  simple_molecule deoxynucleoside diphosphate simple_molecule
  gene dnaAN-recF gene
  RNA dnaAN-recF_mRNA RNA
  gene gdhA gene
  RNA gdhA_mRNA RNA
  simple_molecule guanosine-diphosphate simple_molecule
  simple_molecule ketoglutarate simple_molecule
  gene lysA gene
  RNA lysA_mRNA RNA
  gene lysC gene
  RNA lysC_mRNA RNA
  gene lysP gene
  RNA lysP_mRNA RNA
  simple_molecule lysine simple_molecule
  simple_molecule lysine_Ext simple_molecule
  gene nrdAB-yfaE gene
  RNA nrdAB-yfaE_mRNA RNA
  simple_molecule nucleoside diphosphate simple_molecule
  simple_molecule reduced thioredoxin simple_molecule
  simple_molecule stabilized RecA filament-DNA complex simple_molecule
  simple_molecule suc-coa simple_molecule
  simple_molecule tetrahydrodipicolinate simple_molecule
  simple_molecule thioredoxin disulfide simple_molecule
  simple_molecule unstable RecA filament-DNA complex simple_molecule
  simple_molecule uridine-diphosphate simple_molecule


Reactions       
Showing 45 reactions
ArgP dapB dapB_mRNA
Name: dapB -> dapB_mRNA
Description: Transcription of transcription unit dapB. Reaction activation by ArgP.
Type: transcription
Pathway Components: dapB - ArgP -> dapB_mRNA
Components:
Function Name Type
activator ArgP protein
reactant dapB gene
product dapB_mRNA RNA
ArgP dapD dapD_mRNA
Name: dapD -> dapD_mRNA
Description: Transcription of transcription unit dapD. Reaction activation by ArgP.
Type: transcription
Pathway Components: dapD - ArgP -> dapD_mRNA
Components:
Function Name Type
activator ArgP protein
reactant dapD gene
product dapD_mRNA RNA
ArgP dnaAN-recF dnaAN-recF_mRNA
Name: dnaAN-recF -> dnaAN-recF_mRNA
Description: Transcription of transcription unit dnaAN-recF. Reaction activation by ArgP.
Type: transcription
Pathway Components: dnaAN-recF - ArgP -> dnaAN-recF_mRNA
Components:
Function Name Type
activator ArgP protein
reactant dnaAN-recF gene
product dnaAN-recF_mRNA RNA
ArgP gdhA gdhA_mRNA
Name: gdhA -> gdhA_mRNA
Description: Transcription of transcription unit gdhA. Reaction activation by ArgP.
Type: transcription
Pathway Components: gdhA - ArgP -> gdhA_mRNA
Components:
Function Name Type
activator ArgP protein
reactant gdhA gene
product gdhA_mRNA RNA
ArgP lysA lysA_mRNA
Name: lysA -> lysA_mRNA
Description: Transcription of transcription unit lysA. Reaction activation by ArgP.
Type: transcription
Pathway Components: lysA - ArgP -> lysA_mRNA
Components:
Function Name Type
activator ArgP protein
reactant lysA gene
product lysA_mRNA RNA
ArgP lysC lysC_mRNA
Name: lysC -> lysC_mRNA
Description: Transcription of transcription unit lysC. Reaction activation by ArgP.
Type: transcription
Pathway Components: lysC - ArgP -> lysC_mRNA
Components:
Function Name Type
activator ArgP protein
reactant lysC gene
product lysC_mRNA RNA
ArgP lysP lysP_mRNA
Name: lysP -> lysP_mRNA
Description: Transcription of transcription unit lysP. Reaction activation by ArgP.
Type: transcription
Pathway Components: lysP - ArgP -> lysP_mRNA
Components:
Function Name Type
activator ArgP protein
reactant lysP gene
product lysP_mRNA RNA
ArgP nrdAB-yfaE nrdAB-yfaE_mRNA
Name: nrdAB-yfaE -> nrdAB-yfaE_mRNA
Description: Transcription of transcription unit nrdAB-yfaE. Reaction activation by ArgP.
Type: transcription
Pathway Components: nrdAB-yfaE - ArgP -> nrdAB-yfaE_mRNA
Components:
Function Name Type
activator ArgP protein
reactant nrdAB-yfaE gene
product nrdAB-yfaE_mRNA RNA
arginine + ArgP ArgP-arginine
Name: arginine + ArgP -> ArgP-arginine
Description: Reaction transforming arginine, ArgP into ArgP-arginine
Type: state transition
Pathway Components: arginine + ArgP -> ArgP-arginine
Components:
Function Name Type
reactant ArgP protein
product ArgP-arginine complex
reactant arginine simple_molecule
ArgP-arginine argO argO_mRNA
Name: argO -> argO_mRNA
Description: Transcription of transcription unit argO. Reaction activation by ArgP-arginine.
Type: transcription
Pathway Components: argO - ArgP-arginine -> argO_mRNA
Components:
Function Name Type
activator ArgP-arginine complex
reactant argO gene
product argO_mRNA RNA
ArgP-arginine argP argP_mRNA
Name: argP -> argP_mRNA
Description: Transcription of transcription unit argP. Reaction inhibition by ArgP-arginine.
Type: transcription
Pathway Components: argP - ArgP-arginine -> argP_mRNA
Components:
Function Name Type
inhibitor ArgP-arginine complex
reactant argP gene
product argP_mRNA RNA
lysine + ArgP ArgP-lysine
Name: lysine + ArgP -> ArgP-lysine
Description: Reaction transforming lysine, ArgP into ArgP-lysine
Type: state transition
Pathway Components: lysine + ArgP -> ArgP-lysine
Components:
Function Name Type
reactant ArgP protein
product ArgP-lysine complex
reactant lysine simple_molecule
lysA_mRNA LysA
Name: lysA_mRNA -> LysA
Description: Translation of LysA
Type: translation
Pathway Components: lysA_mRNA -> LysA
Components:
Function Name Type
product LysA protein
reactant lysA_mRNA RNA
L-glutamate LysA lysine M-DAP lysine + CO2
Name: M-DAP -> lysine + CO2
Description: Reaction transforming M-DAP into lysine, CO2
Type: state transition
Pathway Components: M-DAP - LysA - L-glutamate - lysine -> lysine + CO2
Components:
Function Name Type
product CO2 simple_molecule
inhibitor L-glutamate simple_molecule
catalyzer LysA protein
reactant M-DAP simple_molecule
inhibitor lysine simple_molecule
product lysine simple_molecule
gdhA_mRNA GdhA
Name: gdhA_mRNA -> GdhA
Description: Translation of GdhA
Type: translation
Pathway Components: gdhA_mRNA -> GdhA
Components:
Function Name Type
product GdhA protein
reactant gdhA_mRNA RNA
GdhA L-glutamate ketoglutarate + ammonium
Name: L-glutamate -> ketoglutarate + ammonium
Description: Reaction transforming L-glutamate into ketoglutarate, ammonium
Type: state transition
Pathway Components: L-glutamate - GdhA -> ketoglutarate + ammonium
Components:
Function Name Type
catalyzer GdhA protein
reactant L-glutamate simple_molecule
product ammonium simple_molecule
product ketoglutarate simple_molecule
dapB_mRNA DapB
Name: dapB_mRNA -> DapB
Description: Translation of DapB
Type: translation
Pathway Components: dapB_mRNA -> DapB
Components:
Function Name Type
product DapB protein
reactant dapB_mRNA RNA
DapB (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate tetrahydrodipicolinate
Name: (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate -> tetrahydrodipicolinate
Description: Reaction transforming (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate into tetrahydrodipicolinate
Type: state transition
Pathway Components: (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate - DapB -> tetrahydrodipicolinate
Components:
Function Name Type
reactant (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate simple_molecule
catalyzer DapB protein
product tetrahydrodipicolinate simple_molecule
nrdAB-yfaE_mRNA NrdA
Name: nrdAB-yfaE_mRNA -> NrdA
Description: Translation of NrdA
Type: translation
Pathway Components: nrdAB-yfaE_mRNA -> NrdA
Components:
Function Name Type
product NrdA protein
reactant nrdAB-yfaE_mRNA RNA
NrdB + NrdA NrdA-NrdB
Name: NrdB + NrdA -> NrdA-NrdB
Description: Reaction transforming NrdB, NrdA into NrdA-NrdB
Type: state transition
Pathway Components: NrdB + NrdA -> NrdA-NrdB
Components:
Function Name Type
reactant NrdA protein
product NrdA-NrdB complex
reactant NrdB protein
NrdA-NrdB dCDP nucleoside diphosphate + reduced thioredoxin Products
Name: nucleoside diphosphate + reduced thioredoxin -> deoxynucleoside diphosphate + thioredoxin disulfide
Description: Reaction transforming nucleoside diphosphate, reduced thioredoxin into deoxynucleoside diphosphate, thioredoxin disulfide
Type: state transition
Pathway Components: nucleoside diphosphate + reduced thioredoxin - NrdA-NrdB - dCDP -> deoxynucleoside diphosphate + thioredoxin disulfide
Components:
Function Name Type
catalyzer NrdA-NrdB complex
inhibitor dCDP simple_molecule
product deoxynucleoside diphosphate simple_molecule
reactant nucleoside diphosphate simple_molecule
reactant reduced thioredoxin simple_molecule
product thioredoxin disulfide simple_molecule
NrdA-NrdB cytidine-diphosphate + reduced thioredoxin thioredoxin disulfide + dCDP
Name: cytidine-diphosphate + reduced thioredoxin -> thioredoxin disulfide + dCDP
Description: Reaction transforming cytidine-diphosphate, reduced thioredoxin into thioredoxin disulfide, dCDP
Type: state transition
Pathway Components: cytidine-diphosphate + reduced thioredoxin - NrdA-NrdB -> thioredoxin disulfide + dCDP
Components:
Function Name Type
catalyzer NrdA-NrdB complex
reactant cytidine-diphosphate simple_molecule
product dCDP simple_molecule
reactant reduced thioredoxin simple_molecule
product thioredoxin disulfide simple_molecule
NrdA-NrdB reduced thioredoxin + uridine-diphosphate thioredoxin disulfide + dUDP
Name: reduced thioredoxin + uridine-diphosphate -> thioredoxin disulfide + dUDP
Description: Reaction transforming reduced thioredoxin, uridine-diphosphate into thioredoxin disulfide, dUDP
Type: state transition
Pathway Components: reduced thioredoxin + uridine-diphosphate - NrdA-NrdB -> thioredoxin disulfide + dUDP
Components:
Function Name Type
catalyzer NrdA-NrdB complex
product dUDP simple_molecule
reactant reduced thioredoxin simple_molecule
product thioredoxin disulfide simple_molecule
reactant uridine-diphosphate simple_molecule
NrdA-NrdB reduced thioredoxin thioredoxin disulfide + dADP
Name: reduced thioredoxin -> thioredoxin disulfide + dADP
Description: Reaction transforming reduced thioredoxin into thioredoxin disulfide, dADP
Type: state transition
Pathway Components: reduced thioredoxin - NrdA-NrdB -> thioredoxin disulfide + dADP
Components:
Function Name Type
catalyzer NrdA-NrdB complex
product dADP simple_molecule
reactant reduced thioredoxin simple_molecule
product thioredoxin disulfide simple_molecule
NrdA-NrdB guanosine-diphosphate + reduced thioredoxin thioredoxin disulfide + dGDP
Name: guanosine-diphosphate + reduced thioredoxin -> thioredoxin disulfide + dGDP
Description: Reaction transforming guanosine-diphosphate, reduced thioredoxin into thioredoxin disulfide, dGDP
Type: state transition
Pathway Components: guanosine-diphosphate + reduced thioredoxin - NrdA-NrdB -> thioredoxin disulfide + dGDP
Components:
Function Name Type
catalyzer NrdA-NrdB complex
product dGDP simple_molecule
reactant guanosine-diphosphate simple_molecule
reactant reduced thioredoxin simple_molecule
product thioredoxin disulfide simple_molecule
nrdAB-yfaE_mRNA NrdB
Name: nrdAB-yfaE_mRNA -> NrdB
Description: Translation of NrdB
Type: translation
Pathway Components: nrdAB-yfaE_mRNA -> NrdB
Components:
Function Name Type
product NrdB protein
reactant nrdAB-yfaE_mRNA RNA
nrdAB-yfaE_mRNA YfaE
Name: nrdAB-yfaE_mRNA -> YfaE
Description: Translation of YfaE
Type: translation
Pathway Components: nrdAB-yfaE_mRNA -> YfaE
Components:
Function Name Type
product YfaE protein
reactant nrdAB-yfaE_mRNA RNA
dapD_mRNA DapD
Name: dapD_mRNA -> DapD
Description: Translation of DapD
Type: translation
Pathway Components: dapD_mRNA -> DapD
Components:
Function Name Type
product DapD protein
reactant dapD_mRNA RNA
DapD tetrahydrodipicolinate + suc-coa Products
Name: tetrahydrodipicolinate + suc-coa -> N-Succinyl-2-L-amino-6-oxoheptanedioate + coenzyme A
Description: Reaction transforming tetrahydrodipicolinate, suc-coa into N-Succinyl-2-L-amino-6-oxoheptanedioate, coenzyme A
Type: state transition
Pathway Components: tetrahydrodipicolinate + suc-coa - DapD -> N-Succinyl-2-L-amino-6-oxoheptanedioate + coenzyme A
Components:
Function Name Type
catalyzer DapD protein
product N-Succinyl-2-L-amino-6-oxoheptanedioate simple_molecule
product coenzyme A simple_molecule
reactant suc-coa simple_molecule
reactant tetrahydrodipicolinate simple_molecule
lysP_mRNA LysP
Name: lysP_mRNA -> LysP
Description: Translation of LysP
Type: translation
Pathway Components: lysP_mRNA -> LysP
Components:
Function Name Type
product LysP protein
reactant lysP_mRNA RNA
LysP lysine_Ext lysine
Name: lysine_Ext -> lysine
Description: Transport of lysine_Ext through a bacterial membrane, leading to the presence of lysine inside the cell.
Type: transport
Pathway Components: lysine_Ext - LysP -> lysine
Components:
Function Name Type
catalyzer LysP protein
product lysine simple_molecule
reactant lysine_Ext simple_molecule
lysC_mRNA LysC
Name: lysC_mRNA -> LysC
Description: Translation of LysC
Type: translation
Pathway Components: lysC_mRNA -> LysC
Components:
Function Name Type
product LysC protein
reactant lysC_mRNA RNA
LysC lysine aspartate aspartyl-4-P
Name: aspartate -> aspartyl-4-P
Description: Reaction transforming aspartate into aspartyl-4-P
Type: state transition
Pathway Components: aspartate - LysC - lysine -> aspartyl-4-P
Components:
Function Name Type
catalyzer LysC protein
reactant aspartate simple_molecule
product aspartyl-4-P simple_molecule
inhibitor lysine simple_molecule
argO_mRNA ArgO
Name: argO_mRNA -> ArgO
Description: Translation of ArgO
Type: translation
Pathway Components: argO_mRNA -> ArgO
Components:
Function Name Type
product ArgO protein
reactant argO_mRNA RNA
ArgO arginine_Ext arginine
Name: arginine_Ext -> arginine
Description: Transport of arginine_Ext through a bacterial membrane, leading to the presence of arginine inside the cell.
Type: transport
Pathway Components: arginine_Ext - ArgO -> arginine
Components:
Function Name Type
catalyzer ArgO protein
product arginine simple_molecule
reactant arginine_Ext simple_molecule
ArgO canavanine_Ext canavanine
Name: canavanine_Ext -> canavanine
Description: Transport of canavanine_Ext through a bacterial membrane, leading to the presence of canavanine inside the cell.
Type: transport
Pathway Components: canavanine_Ext - ArgO -> canavanine
Components:
Function Name Type
catalyzer ArgO protein
product canavanine simple_molecule
reactant canavanine_Ext simple_molecule
argP_mRNA ArgP
Name: argP_mRNA -> ArgP
Description: Translation of ArgP
Type: translation
Pathway Components: argP_mRNA -> ArgP
Components:
Function Name Type
product ArgP protein
reactant argP_mRNA RNA
dnaAN-recF_mRNA DnaA
Name: dnaAN-recF_mRNA -> DnaA
Description: Translation of DnaA
Type: translation
Pathway Components: dnaAN-recF_mRNA -> DnaA
Components:
Function Name Type
product DnaA protein
reactant dnaAN-recF_mRNA RNA
dnaAN-recF_mRNA DnaN
Name: dnaAN-recF_mRNA -> DnaN
Description: Translation of DnaN
Type: translation
Pathway Components: dnaAN-recF_mRNA -> DnaN
Components:
Function Name Type
product DnaN protein
reactant dnaAN-recF_mRNA RNA
Protein Monomers HolE-DnaQ-DnaE-HolA-HolB-DnaX-DnaN-HolD-HolC
Name: HolE + HolB + DnaX + HolA + DnaQ + DnaN + HolD + HolC + DnaE -> HolE-DnaQ-DnaE-HolA-HolB-DnaX-DnaN-HolD-HolC
Description: Reaction transforming HolE, HolB, DnaX, HolA, DnaQ, DnaN, HolD, HolC, DnaE into HolE-DnaQ-DnaE-HolA-HolB-DnaX-DnaN-HolD-HolC
Type: state transition
Pathway Components: HolE + HolB + DnaX + HolA + DnaQ + DnaN + HolD + HolC + DnaE -> HolE-DnaQ-DnaE-HolA-HolB-DnaX-DnaN-HolD-HolC
Components: Show/Hide Components Table
dnaAN-recF_mRNA RecF
Name: dnaAN-recF_mRNA -> RecF
Description: Translation of RecF
Type: translation
Pathway Components: dnaAN-recF_mRNA -> RecF
Components:
Function Name Type
product RecF protein
reactant dnaAN-recF_mRNA RNA
RecF + RecO + RecR RecF-RecR-RecO
Name: RecF + RecO + RecR -> RecF-RecR-RecO
Description: Reaction transforming RecF, RecO, RecR into RecF-RecR-RecO
Type: state transition
Pathway Components: RecF + RecO + RecR -> RecF-RecR-RecO
Components:
Function Name Type
reactant RecF protein
product RecF-RecR-RecO complex
reactant RecO protein
reactant RecR protein
RecF-RecR-RecO unstable RecA filament-DNA complex stabilized RecA filament-DNA complex
Name: unstable RecA filament-DNA complex -> stabilized RecA filament-DNA complex
Description: Reaction transforming unstable RecA filament-DNA complex into stabilized RecA filament-DNA complex
Type: state transition
Pathway Components: unstable RecA filament-DNA complex - RecF-RecR-RecO -> stabilized RecA filament-DNA complex
Components:
Function Name Type
catalyzer RecF-RecR-RecO complex
product stabilized RecA filament-DNA complex simple_molecule
reactant unstable RecA filament-DNA complex simple_molecule
N-Succinyl-2-L-amino-6-oxoheptanedioate M-DAP
Name: N-Succinyl-2-L-amino-6-oxoheptanedioate -> M-DAP
Description: Transformation of N-Succinyl-2-L-amino-6-oxoheptanedioate into M-DAP by one or more reactions not shown.
Type: complementary pathway reaction
Pathway Components: N-Succinyl-2-L-amino-6-oxoheptanedioate / SUCCINYLDIAMINOPIMTRANS-RXN / SUCCDIAMINOPIMDESUCC-RXN / DIAMINOPIMEPIM-RXN / M-DAP
Components:
Function Name Type
product M-DAP simple_molecule
reactant N-Succinyl-2-L-amino-6-oxoheptanedioate simple_molecule
aspartyl-4-P (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate
Name: aspartyl-4-P -> (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate
Description: Transformation of aspartyl-4-P into (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate by one or more reactions not shown.
Type: complementary pathway reaction
Pathway Components: aspartyl-4-P / ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN / DIHYDRODIPICSYN-RXN / (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate
Components:
Function Name Type
product (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate simple_molecule
reactant aspartyl-4-P simple_molecule



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