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AlsR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
AlsA AlsB AlsC AlsE AlsR D-allose D-allose-6-phosphate D-allose_Ext D-allulose-6-phosphate D-fructose 6-phosphate ribose-5P ribulose-5P RpiB rpiB rpiB_mRNA rpiR-alsBACE rpiR-alsBACE_mRNA AlsR D-allose AlsA AlsC AlsB


Gensor Unit       
Name: AlsR
Description: AlsR negatively regulates the expression of genes involved in D-allose import and catabolic process in the absence of D-allose. The presence of D-allose induces the expression of genes related to D-allose uptake and degradation to D-fructose-6-phosphate (which feeds the glycolysis cycle).
Classification:
Groups: GUs related to carbon source utilization
Gene Ontology Terms (GO): GO:0045892 - negative regulation of transcription, DNA-templated
GO:0044262 - cellular carbohydrate metabolic process
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0003824 - catalytic activity
GO:0016020 - membrane
GO:0042597 - periplasmic space
GO:0016887 - ATPase activity
GO:0003677 - DNA binding
GO:0004751 - ribose-5-phosphate isomerase activity
GO:0030246 - carbohydrate binding
GO:0008786 - allose 6-phosphate isomerase activity
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Components:
Function Name Type
RNA rpiR-alsBACE_mRNA RNA


Reactions       
Showing 14 reactions
rpiB rpiB_mRNA
Name: rpiB -> rpiB_mRNA
Description: Transcription of transcription unit rpiB; reaction inhibition by AlsR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant rpiB gene nd nd
product rpiB_mRNA RNA nd nd
rpiR-alsBACE rpiR-alsBACE_mRNA
Name: rpiR-alsBACE -> rpiR-alsBACE_mRNA
Description: Transcription of transcription unit rpiR-alsBACE; reaction inhibition by AlsR.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant rpiR-alsBACE gene nd nd
product rpiR-alsBACE_mRNA RNA nd nd
AlsR + D-allose AlsR-D-allose
Name: AlsR + D-allose -> AlsR-D-allose
Description: Reaction transforming AlsR, D-allose into AlsR-D-allose
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant AlsR protein nd nd
reactant D-allose simple molecule nd nd
product AlsR-D-allose complex nd nd
rpiR-alsBACE_mRNA AlsB
Name: rpiR-alsBACE_mRNA -> AlsB
Description: Translation of AlsB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant rpiR-alsBACE_mRNA RNA nd nd
product AlsB protein nd nd
AlsA + AlsC + AlsB AlsA-AlsC-AlsB
Name: AlsA + AlsC + AlsB -> AlsA-AlsC-AlsB
Description: Reaction transforming AlsA, AlsC, AlsB into AlsA-AlsC-AlsB
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant AlsC protein nd nd
reactant AlsA protein nd nd
reactant AlsB protein nd nd
product AlsA-AlsC-AlsB complex nd nd
D-allose_Ext D-allose
Name: D-allose_Ext -> D-allose
Description: Transport of D-allose_Ext through a bacterial membrane, leading to the presence of D-allose inside the compartment.
Type: transport
Components:
Function Name Type Evidence Reference(s)
product D-allose simple molecule nd nd
reactant D-allose_Ext simple molecule nd nd
rpiR-alsBACE_mRNA AlsR
Name: rpiR-alsBACE_mRNA -> AlsR
Description: Translation of AlsR
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant rpiR-alsBACE_mRNA RNA nd nd
product AlsR protein nd nd
rpiR-alsBACE_mRNA AlsC
Name: rpiR-alsBACE_mRNA -> AlsC
Description: Translation of AlsC
Type: translation
Components:
Function Name Type Evidence Reference(s)
product AlsC protein nd nd
reactant rpiR-alsBACE_mRNA RNA nd nd
rpiR-alsBACE_mRNA AlsE
Name: rpiR-alsBACE_mRNA -> AlsE
Description: Translation of AlsE
Type: translation
Components:
Function Name Type Evidence Reference(s)
product AlsE protein nd nd
reactant rpiR-alsBACE_mRNA RNA nd nd
D-allulose-6-phosphate D-fructose 6-phosphate
Name: D-allulose-6-phosphate -> D-fructose 6-phosphate
Description: Reaction transforming D-allulose-6-phosphate into D-fructose 6-phosphate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product D-fructose 6-phosphate simple molecule nd nd
reactant D-allulose-6-phosphate simple molecule nd nd
rpiB_mRNA RpiB
Name: rpiB_mRNA -> RpiB
Description: Translation of RpiB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant rpiB_mRNA RNA nd nd
product RpiB protein nd nd
D-allose-6-phosphate D-allulose-6-phosphate
Name: D-allose-6-phosphate -> D-allulose-6-phosphate
Description: Reaction transforming D-allose-6-phosphate into D-allulose-6-phosphate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product D-allulose-6-phosphate simple molecule nd nd
reactant D-allose-6-phosphate simple molecule nd nd
D-ribose 5-phosphate D-ribulose 5-phosphate
Name: D-ribose 5-phosphate -> D-ribulose 5-phosphate
Description: Reaction transforming D-ribose 5-phosphate into D-ribulose 5-phosphate
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant D-ribose 5-phosphate simple molecule nd nd
product D-ribulose 5-phosphate simple molecule nd nd
rpiR-alsBACE_mRNA AlsA
Name: rpiR-alsBACE_mRNA -> AlsA
Description: Translation of AlsA
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant rpiR-alsBACE_mRNA RNA nd nd
product AlsA protein nd nd



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