RegulonDB RegulonDB

AcrR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
AcrA AcrB AcrD AcrR ethidium This Gensor Unit is not yet available Proflavin R6G TolC a drug a drug_Ext acrAB acrAB_mRNA acrR acrR_mRNA micF micF_mRNA AcrR ethidium AcrR R6G AcrR Proflavin AcrA TolC AcrB AcrD AcrA TolC


Gensor Unit       
Name: AcrR
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): biological_process GO:0015721 - bile acid and bile salt transport
GO:0071236 - cellular response to antibiotic
GO:0046618 - drug export
GO:0006855 - drug transmembrane transport
GO:0045892 - negative regulation of transcription, DNA-templated
GO:0045893 - positive regulation of transcription, DNA-templated
Read more >
cellular_component GO:0005737 - cytoplasm
GO:1990281 - efflux pump complex
GO:0005887 - integral component of plasma membrane
GO:0031226 - intrinsic component of plasma membrane
GO:0016020 - membrane
GO:0030288 - outer membrane-bounded periplasmic space
GO:0005886 - plasma membrane
Read more >
molecular_function GO:0051537 - 2 iron, 2 sulfur cluster binding
GO:0003677 - DNA binding
GO:0003700 - DNA binding transcription factor activity
GO:0001108 - bacterial-type RNA polymerase holo enzyme binding
GO:0000986 - bacterial-type proximal promoter sequence-specific DNA binding
GO:0008144 - drug binding
GO:0015238 - drug transmembrane transporter activity
Read more >
Components: Show/Hide Components Table (35 more...)
Function Name Type
protein AcrA protein
complex AcrA-TolC-AcrB complex
protein AcrB protein
protein AcrD protein
complex AcrD-AcrA-TolC complex
protein AcrR protein
complex AcrR-ethidium complex
complex AcrR-proflavin complex
complex AcrR-rhodamine 6G complex
protein MarA protein
protein MarB protein
protein MarR protein
protein RNA:MicF protein
protein SoxR protein
protein SoxS protein
protein TolC protein
gene acrAB gene
RNA acrAB_mRNA RNA
gene acrR gene
RNA acrR_mRNA RNA
simple_molecule chenodiol simple_molecule
simple_molecule chenodiol_Ext simple_molecule
simple_molecule drug simple_molecule
simple_molecule drug_Ext simple_molecule
simple_molecule ethidium simple_molecule
gene marRAB gene
RNA marRAB_mRNA RNA
gene micF gene
RNA micF_mRNA RNA
simple_molecule proflavin simple_molecule
simple_molecule rhodamine 6G simple_molecule
gene soxR gene
RNA soxR_mRNA RNA
gene soxS gene
RNA soxS_mRNA RNA


Reactions       
Showing 22 reactions
AcrR acrAB acrAB_mRNA
Name: acrAB -> acrAB_mRNA
Description: Transcription of transcription unit acrAB. Reaction inhibition by AcrR.
Type: transcription
Pathway Components: acrAB - AcrR -> acrAB_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor AcrR protein nd nd
reactant acrAB gene nd nd
product acrAB_mRNA RNA nd nd
AcrR acrR acrR_mRNA
Name: acrR -> acrR_mRNA
Description: Transcription of transcription unit acrR. Reaction inhibition by AcrR.
Type: transcription
Pathway Components: acrR - AcrR -> acrR_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor AcrR protein nd nd
reactant acrR gene nd nd
product acrR_mRNA RNA nd nd
AcrR marRAB marRAB_mRNA
Name: marRAB -> marRAB_mRNA
Description: Transcription of transcription unit marRAB. Reaction inhibition by AcrR.
Type: transcription
Pathway Components: marRAB - AcrR -> marRAB_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor AcrR protein nd nd
reactant marRAB gene nd nd
product marRAB_mRNA RNA nd nd
AcrR micF micF_mRNA
Name: micF -> micF_mRNA
Description: Transcription of transcription unit micF. Reaction inhibition by AcrR.
Type: transcription
Pathway Components: micF - AcrR -> micF_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor AcrR protein nd nd
reactant micF gene nd nd
product micF_mRNA RNA nd nd
AcrR soxR soxR_mRNA
Name: soxR -> soxR_mRNA
Description: Transcription of transcription unit soxR. Reaction inhibition by AcrR.
Type: transcription
Pathway Components: soxR - AcrR -> soxR_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor AcrR protein nd nd
reactant soxR gene nd nd
product soxR_mRNA RNA nd nd
AcrR soxS soxS_mRNA
Name: soxS -> soxS_mRNA
Description: Transcription of transcription unit soxS. Reaction inhibition by AcrR.
Type: transcription
Pathway Components: soxS - AcrR -> soxS_mRNA
Components:
Function Name Type Evidence Reference(s)
inhibitor AcrR protein nd nd
reactant soxS gene nd nd
product soxS_mRNA RNA nd nd
ethidium + AcrR AcrR-ethidium
Name: ethidium + AcrR -> AcrR-ethidium
Description: Reaction transforming ethidium, AcrR into AcrR-ethidium
Type: state transition
Pathway Components: ethidium + AcrR -> AcrR-ethidium
Components:
Function Name Type Evidence Reference(s)
reactant AcrR protein nd nd
product AcrR-ethidium complex nd nd
reactant ethidium simple_molecule nd nd
proflavin + AcrR AcrR-proflavin
Name: proflavin + AcrR -> AcrR-proflavin
Description: Reaction transforming proflavin, AcrR into AcrR-proflavin
Type: state transition
Pathway Components: proflavin + AcrR -> AcrR-proflavin
Components:
Function Name Type Evidence Reference(s)
reactant AcrR protein nd nd
product AcrR-proflavin complex nd nd
reactant proflavin simple_molecule nd nd
rhodamine 6G + AcrR AcrR-rhodamine 6G
Name: rhodamine 6G + AcrR -> AcrR-rhodamine 6G
Description: Reaction transforming rhodamine 6G, AcrR into AcrR-rhodamine 6G
Type: state transition
Pathway Components: rhodamine 6G + AcrR -> AcrR-rhodamine 6G
Components:
Function Name Type Evidence Reference(s)
reactant AcrR protein nd nd
product AcrR-rhodamine 6G complex nd nd
reactant rhodamine 6G simple_molecule nd nd
marRAB_mRNA MarR
Name: marRAB_mRNA -> MarR
Description: Translation of MarR
Type: translation
Pathway Components: marRAB_mRNA -> MarR
Components:
Function Name Type Evidence Reference(s)
product MarR protein nd nd
reactant marRAB_mRNA RNA nd nd
marRAB_mRNA MarA
Name: marRAB_mRNA -> MarA
Description: Translation of MarA
Type: translation
Pathway Components: marRAB_mRNA -> MarA
Components:
Function Name Type Evidence Reference(s)
product MarA protein nd nd
reactant marRAB_mRNA RNA nd nd
marRAB_mRNA MarB
Name: marRAB_mRNA -> MarB
Description: Translation of MarB
Type: translation
Pathway Components: marRAB_mRNA -> MarB
Components:
Function Name Type Evidence Reference(s)
product MarB protein nd nd
reactant marRAB_mRNA RNA nd nd
acrR_mRNA AcrR
Name: acrR_mRNA -> AcrR
Description: Translation of AcrR
Type: translation
Pathway Components: acrR_mRNA -> AcrR
Components:
Function Name Type Evidence Reference(s)
product AcrR protein nd nd
reactant acrR_mRNA RNA nd nd
soxR_mRNA SoxR
Name: soxR_mRNA -> SoxR
Description: Translation of SoxR
Type: translation
Pathway Components: soxR_mRNA -> SoxR
Components:
Function Name Type Evidence Reference(s)
product SoxR protein nd nd
reactant soxR_mRNA RNA nd nd
micF_mRNA RNA:MicF
Name: micF_mRNA -> RNA:MicF
Description: Translation of RNA:MicF
Type: translation
Pathway Components: micF_mRNA -> RNA:MicF
Components:
Function Name Type Evidence Reference(s)
product RNA:MicF protein nd nd
reactant micF_mRNA RNA nd nd
soxS_mRNA SoxS
Name: soxS_mRNA -> SoxS
Description: Translation of SoxS
Type: translation
Pathway Components: soxS_mRNA -> SoxS
Components:
Function Name Type Evidence Reference(s)
product SoxS protein nd nd
reactant soxS_mRNA RNA nd nd
acrAB_mRNA AcrA
Name: acrAB_mRNA -> AcrA
Description: Translation of AcrA
Type: translation
Pathway Components: acrAB_mRNA -> AcrA
Components:
Function Name Type Evidence Reference(s)
product AcrA protein nd nd
reactant acrAB_mRNA RNA nd nd
AcrD + AcrA + TolC AcrD-AcrA-TolC
Name: AcrD + AcrA + TolC -> AcrD-AcrA-TolC
Description: Reaction transforming AcrD, AcrA, TolC into AcrD-AcrA-TolC
Type: state transition
Pathway Components: AcrD + AcrA + TolC -> AcrD-AcrA-TolC
Components:
Function Name Type Evidence Reference(s)
reactant AcrA protein nd nd
reactant AcrD protein nd nd
product AcrD-AcrA-TolC complex nd nd
reactant TolC protein nd nd
AcrA-TolC-AcrB AcrD-AcrA-TolC drug_Ext drug
Name: drug_Ext -> drug
Description: Transport of drug_Ext through a bacterial membrane, leading to the presence of drug inside the cell.
Type: transport
Pathway Components: drug_Ext - AcrA-TolC-AcrB - AcrD-AcrA-TolC -> drug
Components:
Function Name Type Evidence Reference(s)
catalyzer AcrA-TolC-AcrB complex nd nd
catalyzer AcrD-AcrA-TolC complex nd nd
product drug simple_molecule nd nd
reactant drug_Ext simple_molecule nd nd
AcrB + AcrA + TolC AcrA-TolC-AcrB
Name: AcrB + AcrA + TolC -> AcrA-TolC-AcrB
Description: Reaction transforming AcrB, AcrA, TolC into AcrA-TolC-AcrB
Type: state transition
Pathway Components: AcrB + AcrA + TolC -> AcrA-TolC-AcrB
Components:
Function Name Type Evidence Reference(s)
reactant AcrA protein nd nd
product AcrA-TolC-AcrB complex nd nd
reactant AcrB protein nd nd
reactant TolC protein nd nd
AcrA-TolC-AcrB chenodiol_Ext chenodiol
Name: chenodiol_Ext -> chenodiol
Description: Transport of chenodiol_Ext through a bacterial membrane, leading to the presence of chenodiol inside the cell.
Type: transport
Pathway Components: chenodiol_Ext - AcrA-TolC-AcrB -> chenodiol
Components:
Function Name Type Evidence Reference(s)
catalyzer AcrA-TolC-AcrB complex nd nd
product chenodiol simple_molecule nd nd
reactant chenodiol_Ext simple_molecule nd nd
acrAB_mRNA AcrB
Name: acrAB_mRNA -> AcrB
Description: Translation of AcrB
Type: translation
Pathway Components: acrAB_mRNA -> AcrB
Components:
Function Name Type Evidence Reference(s)
product AcrB protein nd nd
reactant acrAB_mRNA RNA nd nd



RegulonDB