RegulonDB RegulonDB

Ada Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
1-ethyladenine ketoglutarate 3-methylcrotonyl-CoA Ada AidB AlkA AlkB DnaN 1-methyladenine N3-methylcytosine DNA-base-CH3 a nucleobase within DNA a reduced ETF acetaldehyde ada-alkB ada-alkB_mRNA adenine aidB aidB_mRNA alkA alkA_mRNA an alkylated DNA a base(2) an oxidized ETF cytosine formol isovaleryl-CoA oxygen succinate oxygen oxygen CO2 CO2 oxygen Ada


Gensor Unit       
Name: Ada
Classification:
Groups: Unclassified Gensor Units
Gene Ontology Terms (GO): GO:0070989 - oxidative demethylation
GO:0045892 - negative regulation of transcription, DNA-templated
GO:0051213 - dioxygenase activity
GO:0035552 - oxidative single-stranded DNA demethylation
GO:0035553 - oxidative single-stranded RNA demethylation
GO:0008270 - zinc ion binding
GO:0003700 - transcription factor activity, sequence-specific DNA binding
GO:0003824 - catalytic activity
GO:0003995 - acyl-CoA dehydrogenase activity
GO:0016491 - oxidoreductase activity
GO:0016706 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
Read more >
Components:
Function Name Type
simple molecule suc simple molecule


Reactions       
Showing 13 reactions
ada-alkB ada-alkB_mRNA
Name: ada-alkB -> ada-alkB_mRNA
Description: Transcription of transcription unit ada-alkB; reaction inhibition by Ada.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
product ada-alkB_mRNA RNA nd nd
reactant ada-alkB gene nd nd
aidB aidB_mRNA
Name: aidB -> aidB_mRNA
Description: Transcription of transcription unit aidB; reaction activation by Ada.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant aidB gene nd nd
product aidB_mRNA RNA nd nd
alkA alkA_mRNA
Name: alkA -> alkA_mRNA
Description: Transcription of transcription unit alkA; reaction activation by Ada.
Type: transcription
Components:
Function Name Type Evidence Reference(s)
reactant alkA gene nd nd
product alkA_mRNA RNA nd nd
ada-alkB_mRNA AlkB
Name: ada-alkB_mRNA -> AlkB
Description: Translation of AlkB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant ada-alkB_mRNA RNA nd nd
product AlkB protein nd nd
DNA-base-CH3 + oxygen + ketoglutarate a nucleobase within DNA + CO2 + formol + suc
Name: DNA-base-CH3 + oxygen + ketoglutarate -> a nucleobase within DNA + CO2 + formol + suc
Description: Reaction transforming DNA-base-CH3, oxygen, ketoglutarate into a nucleobase within DNA, CO2 , formol , suc
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant ketoglutarate simple molecule nd nd
reactant DNA-base-CH3 simple molecule nd nd
product CO2 simple molecule nd nd
product formol simple molecule nd nd
reactant oxygen simple molecule nd nd
product a nucleobase within DNA simple molecule nd nd
product suc simple molecule nd nd
1-ethyladenine + oxygen + ketoglutarate adenine + CO2 + acetaldehyde + suc
Name: 1-ethyladenine + oxygen + ketoglutarate -> adenine + CO2 + acetaldehyde + suc
Description: Reaction transforming 1-ethyladenine, oxygen, ketoglutarate into adenine, CO2 , acetaldehyde , suc
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product suc simple molecule nd nd
reactant ketoglutarate simple molecule nd nd
product CO2 simple molecule nd nd
product acetaldehyde simple molecule nd nd
reactant 1-ethyladenine simple molecule nd nd
reactant oxygen simple molecule nd nd
product adenine simple molecule nd nd
N3-methylcytosine + oxygen + ketoglutarate cytosine + CO2 + formol + suc
Name: N3-methylcytosine + oxygen + ketoglutarate -> cytosine + CO2 + formol + suc
Description: Reaction transforming N3-methylcytosine, oxygen, ketoglutarate into cytosine, CO2 , formol , suc
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant oxygen simple molecule nd nd
product suc simple molecule nd nd
product formol simple molecule nd nd
product cytosine simple molecule nd nd
reactant N3-methylcytosine simple molecule nd nd
reactant ketoglutarate simple molecule nd nd
product CO2 simple molecule nd nd
1-methyladenine + oxygen + ketoglutarate adenine + CO2 + formol + suc
Name: 1-methyladenine + oxygen + ketoglutarate -> adenine + CO2 + formol + suc
Description: Reaction transforming 1-methyladenine, oxygen, ketoglutarate into adenine, CO2 , formol , suc
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product suc simple molecule nd nd
reactant oxygen simple molecule nd nd
reactant ketoglutarate simple molecule nd nd
product formol simple molecule nd nd
product adenine simple molecule nd nd
product CO2 simple molecule nd nd
reactant 1-methyladenine simple molecule nd nd
aidB_mRNA AidB
Name: aidB_mRNA -> AidB
Description: Translation of AidB
Type: translation
Components:
Function Name Type Evidence Reference(s)
reactant aidB_mRNA RNA nd nd
product AidB protein nd nd
isovaleryl-CoA + an oxidized ETF 3-methylcrotonyl-CoA + a reduced ETF
Name: isovaleryl-CoA + an oxidized ETF -> 3-methylcrotonyl-CoA + a reduced ETF
Description: Reaction transforming isovaleryl-CoA, an oxidized ETF into 3-methylcrotonyl-CoA, a reduced ETF
Type: state transition
Components:
Function Name Type Evidence Reference(s)
reactant an oxidized ETF simple molecule nd nd
reactant isovaleryl-CoA simple molecule nd nd
product a reduced ETF simple molecule nd nd
product 3-methylcrotonyl-CoA simple molecule nd nd
ada-alkB_mRNA Ada
Name: ada-alkB_mRNA -> Ada
Description: Translation of Ada
Type: translation
Components:
Function Name Type Evidence Reference(s)
product Ada protein nd nd
reactant ada-alkB_mRNA RNA nd nd
alkA_mRNA AlkA
Name: alkA_mRNA -> AlkA
Description: Translation of AlkA
Type: translation
Components:
Function Name Type Evidence Reference(s)
product AlkA protein nd nd
reactant alkA_mRNA RNA nd nd
an alkylated DNA DNA(N) + a base(2)
Name: an alkylated DNA -> DNA(N) + a base(2)
Description: Reaction transforming an alkylated DNA into DNA(N), a base(2)
Type: state transition
Components:
Function Name Type Evidence Reference(s)
product a base(2) simple molecule nd nd
reactant an alkylated DNA simple molecule nd nd
product DNA(N) simple molecule nd nd



RegulonDB