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UvrY Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
phosphate LuxS keto-D-fructose 6-phosphate_Ext uhpT_mRNA ydeP csrB_mRNA glucose-6-P_Ext S-Ribosylhomocysteine RNA:CsrB homo-cys csrB uhpT GAP_Ext RNA:CsrC luxS_mRNA CsrC ydeP_mRNA UhpT luxS csrC UvrY YdeP GAP glucose-6-P AI-2 mannopyranose-6-P_Ext keto-D-fructose 6-phosphate csrC_mRNA CsrB UvrY mannopyranose-6-P phosphate


Gensor Unit       
Name: UvrY
Classification:
Groups: Function unknown
Gene Ontology Terms (GO): biological_process GO:0019284 - L-methionine salvage from S-adenosylmethionine
GO:0008643 - carbohydrate transport
GO:0015760 - glucose-6-phosphate transport
GO:0015712 - hexose phosphate transport
GO:1902201 - negative regulation of bacterial-type flagellum-dependent cell motility
GO:1904572 - negative regulation of mRNA binding
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cellular_component GO:0005829 - cytosol
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0016020 - membrane
GO:0030288 - outer membrane-bounded periplasmic space
GO:0005886 - plasma membrane
molecular_function GO:0051539 - 4 iron, 4 sulfur cluster binding
GO:0043768 - S-ribosylhomocysteine lyase activity
GO:0003824 - catalytic activity
GO:0008863 - formate dehydrogenase (NAD+) activity
GO:0015526 - hexose-phosphate:inorganic phosphate antiporter activity
GO:0005506 - iron ion binding
GO:0051536 - iron-sulfur cluster binding
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Components:
  Function Name Type
  simple_molecule AI-2 simple_molecule
  protein CsrB protein
  protein CsrC protein
  simple_molecule GAP simple_molecule
  simple_molecule GAP_Ext simple_molecule
  protein LuxS protein
  protein RNA:CsrB protein
  protein RNA:CsrC protein
  simple_molecule S-Ribosylhomocysteine simple_molecule
  protein UhpT protein
  protein UvrY protein
  complex UvrY-phosphate complex
  protein YdeP protein
  gene csrB gene
  RNA csrB_mRNA RNA
  gene csrC gene
  RNA csrC_mRNA RNA
  simple_molecule glucose-6-P simple_molecule
  simple_molecule glucose-6-P_Ext simple_molecule
  simple_molecule homo-cys simple_molecule
  simple_molecule keto-D-fructose 6-phosphate simple_molecule
  simple_molecule keto-D-fructose 6-phosphate_Ext simple_molecule
  gene luxS gene
  RNA luxS_mRNA RNA
  simple_molecule mannopyranose-6-P simple_molecule
  simple_molecule mannopyranose-6-P_Ext simple_molecule
  simple_molecule phosphate simple_molecule
  gene uhpT gene
  RNA uhpT_mRNA RNA
  gene ydeP gene
  RNA ydeP_mRNA RNA


Reactions       
Showing 18 reactions
phosphate + UvrY UvrY-phosphate
Name: phosphate + UvrY -> UvrY-phosphate
Description: Reaction transforming phosphate, UvrY into UvrY-phosphate
Type: state transition
Pathway Components: phosphate + UvrY -> UvrY-phosphate
Components:
Function Name Type
reactant UvrY protein
product UvrY-phosphate complex
reactant phosphate simple_molecule
UvrY-phosphate csrB csrB_mRNA
Name: csrB -> csrB_mRNA
Description: Transcription of transcription unit csrB. Reaction activation by UvrY-phosphate.
Type: transcription
Pathway Components: csrB - UvrY-phosphate -> csrB_mRNA
Components:
Function Name Type
activator UvrY-phosphate complex
reactant csrB gene
product csrB_mRNA RNA
UvrY-phosphate csrC csrC_mRNA
Name: csrC -> csrC_mRNA
Description: Transcription of transcription unit csrC. Reaction activation by UvrY-phosphate.
Type: transcription
Pathway Components: csrC - UvrY-phosphate -> csrC_mRNA
Components:
Function Name Type
activator UvrY-phosphate complex
reactant csrC gene
product csrC_mRNA RNA
UvrY-phosphate luxS luxS_mRNA
Name: luxS -> luxS_mRNA
Description: Transcription of transcription unit luxS. Reaction activation by UvrY-phosphate.
Type: transcription
Pathway Components: luxS - UvrY-phosphate -> luxS_mRNA
Components:
Function Name Type
activator UvrY-phosphate complex
reactant luxS gene
product luxS_mRNA RNA
UvrY-phosphate uhpT uhpT_mRNA
Name: uhpT -> uhpT_mRNA
Description: Transcription of transcription unit uhpT. Reaction activation by UvrY-phosphate.
Type: transcription
Pathway Components: uhpT - UvrY-phosphate -> uhpT_mRNA
Components:
Function Name Type
activator UvrY-phosphate complex
reactant uhpT gene
product uhpT_mRNA RNA
UvrY-phosphate ydeP ydeP_mRNA
Name: ydeP -> ydeP_mRNA
Description: Transcription of transcription unit ydeP. Reaction activation by UvrY-phosphate.
Type: transcription
Pathway Components: ydeP - UvrY-phosphate -> ydeP_mRNA
Components:
Function Name Type
activator UvrY-phosphate complex
reactant ydeP gene
product ydeP_mRNA RNA
ydeP_mRNA YdeP
Name: ydeP_mRNA -> YdeP
Description: Translation of YdeP
Type: translation
Pathway Components: ydeP_mRNA -> YdeP
Components:
Function Name Type
product YdeP protein
reactant ydeP_mRNA RNA
csrB_mRNA RNA:CsrB
Name: csrB_mRNA -> RNA:CsrB
Description: Translation of RNA:CsrB
Type: translation
Pathway Components: csrB_mRNA -> RNA:CsrB
Components:
Function Name Type
product RNA:CsrB protein
reactant csrB_mRNA RNA
csrB_mRNA CsrB
Name: csrB_mRNA -> CsrB
Description: Translation of CsrB
Type: translation
Pathway Components: csrB_mRNA -> CsrB
Components:
Function Name Type
product CsrB protein
reactant csrB_mRNA RNA
csrC_mRNA RNA:CsrC
Name: csrC_mRNA -> RNA:CsrC
Description: Translation of RNA:CsrC
Type: translation
Pathway Components: csrC_mRNA -> RNA:CsrC
Components:
Function Name Type
product RNA:CsrC protein
reactant csrC_mRNA RNA
csrC_mRNA CsrC
Name: csrC_mRNA -> CsrC
Description: Translation of CsrC
Type: translation
Pathway Components: csrC_mRNA -> CsrC
Components:
Function Name Type
product CsrC protein
reactant csrC_mRNA RNA
luxS_mRNA LuxS
Name: luxS_mRNA -> LuxS
Description: Translation of LuxS
Type: translation
Pathway Components: luxS_mRNA -> LuxS
Components:
Function Name Type
product LuxS protein
reactant luxS_mRNA RNA
LuxS S-Ribosylhomocysteine homo-cys + AI-2
Name: S-Ribosylhomocysteine -> homo-cys + AI-2
Description: Reaction transforming S-Ribosylhomocysteine into homo-cys, AI-2
Type: state transition
Pathway Components: S-Ribosylhomocysteine - LuxS -> homo-cys + AI-2
Components:
Function Name Type
product AI-2 simple_molecule
catalyzer LuxS protein
reactant S-Ribosylhomocysteine simple_molecule
product homo-cys simple_molecule
uhpT_mRNA UhpT
Name: uhpT_mRNA -> UhpT
Description: Translation of UhpT
Type: translation
Pathway Components: uhpT_mRNA -> UhpT
Components:
Function Name Type
product UhpT protein
reactant uhpT_mRNA RNA
UhpT glucose-6-P_Ext glucose-6-P
Name: glucose-6-P_Ext -> glucose-6-P
Description: Transport of glucose-6-P_Ext through a bacterial membrane, leading to the presence of glucose-6-P inside the cell.
Type: transport
Pathway Components: glucose-6-P_Ext - UhpT -> glucose-6-P
Components:
Function Name Type
catalyzer UhpT protein
product glucose-6-P simple_molecule
reactant glucose-6-P_Ext simple_molecule
UhpT mannopyranose-6-P_Ext mannopyranose-6-P
Name: mannopyranose-6-P_Ext -> mannopyranose-6-P
Description: Transport of mannopyranose-6-P_Ext through a bacterial membrane, leading to the presence of mannopyranose-6-P inside the cell.
Type: transport
Pathway Components: mannopyranose-6-P_Ext - UhpT -> mannopyranose-6-P
Components:
Function Name Type
catalyzer UhpT protein
product mannopyranose-6-P simple_molecule
reactant mannopyranose-6-P_Ext simple_molecule
UhpT keto-D-fructose 6-phosphate_Ext keto-D-fructose 6-phosphate
Name: keto-D-fructose 6-phosphate_Ext -> keto-D-fructose 6-phosphate
Description: Transport of keto-D-fructose 6-phosphate_Ext through a bacterial membrane, leading to the presence of keto-D-fructose 6-phosphate inside the cell.
Type: transport
Pathway Components: keto-D-fructose 6-phosphate_Ext - UhpT -> keto-D-fructose 6-phosphate
Components:
Function Name Type
catalyzer UhpT protein
product keto-D-fructose 6-phosphate simple_molecule
reactant keto-D-fructose 6-phosphate_Ext simple_molecule
UhpT GAP_Ext GAP
Name: GAP_Ext -> GAP
Description: Transport of GAP_Ext through a bacterial membrane, leading to the presence of GAP inside the cell.
Type: transport
Pathway Components: GAP_Ext - UhpT -> GAP
Components:
Function Name Type
product GAP simple_molecule
reactant GAP_Ext simple_molecule
catalyzer UhpT protein
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