RegulonDB RegulonDB 10.8: Operon Form
   

norR operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: norR
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: norR
Gene(s): norR   Genome Browser M3D Gene expression COLOMBOS
Note(s): In assay experiments, it was demonstrated that disruption of any one of the three sites of the NorR transcriptional regulator prevented autogenous repression of norR transcription. All three sites are required not only for activation of the norVW operon but also for repression of the norR gene, since NorR acts cooperatively Tucker NP,2006.
Evidence: [AISDTU] Automated inference that a single-gene directon is a transcription unit
Promoter
Name: norRp
+1: 2832307
Distance from start of the gene: 18
Sequence: ttaatgagtagtcaaaatgactatcaatcaaatggtcgatatgacaatatctatagtcaaAttgacagtgaggcaaagatg
Evidence: [TIM]
Reference(s): [1] Tucker NP., et al., 2006
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal NorR repressor norRp 2832301 2832313 1.0 caatatctatAGTCAAATTGACAgtgaggcaaa nd [AIBSCS], [BPP], [CV(GEA)], [CV(GEA)], [GEA] [1], [2], [3], [4]
proximal NorR repressor norRp 2832322 2832334 -21.0 tcaatcaaatGGTCGATATGACAatatctatag nd [AIBSCS], [BPP], [CV(GEA)], [CV(GEA)], [GEA] [1], [2], [3], [4]
proximal NorR repressor norRp 2832346 2832358 -45.0 attaatgagtAGTCAAAATGACTatcaatcaaa nd [AIBSCS], [BPP], [CV(GEA)], [CV(GEA)], [GEA] [1], [2], [3], [4]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal NsrR repressor norRp 2832282 2832293 21.0 acagtgaggcAAAGATGAGTTTttccgttgat nd [APIORCISFBSCS], [CV(GEA)], [GEA] [5]


Transcription unit       
Name: norR
Gene(s): norR   Genome Browser M3D Gene expression COLOMBOS
Evidence: [AISDTU] Automated inference that a single-gene directon is a transcription unit


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Translational
Strand: reverse
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -8.4 2832302 2832333 caatcaaatgGTCGATATGACAATATCTATAGTCAAATTGAcagtgaggca
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"





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