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Name: | appY |
Gene(s): | appY Genome Browser M3D Gene expression COLOMBOS |
Evidence: | [ICWHO] Inferred computationally without human oversight |
Promoter | |
Name: | appYp1 |
+1: | 583567 |
Sigma Factor: | Sigma70 Sigmulon |
Distance from start of the gene: | 114 |
Sequence: |
aataaaaaacaacatacatataataatttaatcttaaatgaaatttattaaaatttgcaaActataattttgtgtataaaa -35 -10 +1 |
Evidence: |
[AIPP] [ICWHO] |
Reference(s): | [1] Huerta AM., et al., 2003 |
Name: | appY |
Gene(s): | appY Genome Browser M3D Gene expression COLOMBOS |
Evidence: | [BTEI] Boundaries of transcription experimentally identified [IEP] Inferred from expression pattern |
Reference(s): | [4] Maciag A., et al., 2011 |
Promoter | |
Name: | appYp3 |
+1: | 583580 |
Sigma Factor: | Sigma70 Sigmulon |
Distance from start of the gene: | 101 |
Sequence: |
atacatataataatttaatcttaaatgaaatttattaaaatttgcaaactataattttgtGtataaaaatataaatgcaca -10 +1 |
Evidence: |
[IHBCE] [TIM] |
Reference(s): | [5] Rangarajan AA., et al., 2018 |
Name: | appY | |||||||||
Gene(s): | appY Genome Browser M3D Gene expression COLOMBOS | |||||||||
Note(s): | appY is positively regulated by RpoS and ArcA in anaerobiosis and also is induced by phosphate starvation and during entry into stationary phase Atlung T,1997. Brondsted L,1996 | |||||||||
Evidence: | [IEP] Inferred from expression pattern | |||||||||
Reference(s): | [4] Maciag A., et al., 2011 | |||||||||
Promoter | ||||||||||
Name: | appYp2 | |||||||||
+1: | 583656 | |||||||||
Sigma Factor: | Sigma38 Sigmulon | |||||||||
Distance from start of the gene: | 25 | |||||||||
Sequence: |
gcacatcatcctgattatgattgtgtatttaattggttgttatttgactactatcaacttGttttaattttatgataggtg -10 +1 |
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Note(s): | Based on ChIP-microarray analysis, it was shown that StpA binds to the promoter region in appYp2 Atlung T,1996. Uyar E, Kurokawa K, Yoshimura M, Ishikawa S, Ogasawara N, Oshima T,2009 qRT-PCR revealed a strong 75-fold repression of appY by H-NS and more than 1,000-fold repression by H-NS/StpA Rangarajan AA,2018 Transcription directed across H-NS binding regions relieves H-NS-mediated (and H-NS/StpA-mediated) repression of promoters such as proVp3, pdeLp3, and appYp2, and there is a correlation between transcription across the H-NS-bound region and derepression where RNA polymerase is able to remodel the H-NS complex and/or dislodge H-NS from the DNA and thus relieve repression Rangarajan AA,2018 |
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Evidence: |
[HTTIM] [IEP] [IHBCE] |
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Reference(s): | [4] Maciag A., et al., 2011 |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
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LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
remote | ArcA-phosphorylated | activator | appYp2 | 583454 | 583464 | -197.0 | agtgagtttaTGTTAATAAAAagcatagtaa | nd | [AIBSCS] | [6] |
Reference(s) |
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