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Name: | nrdHIEF | ||||||||||
Synonym(s): | nrdEF | ||||||||||
Gene(s): | nrdH, nrdI, nrdE, nrdF Genome Browser M3D Gene expression COLOMBOS | ||||||||||
Note(s): | nrdHIEF is induced under H2O2 stress conditions (oxidative stress) Martin JE,2011 Fur, NrdR, and IscR control nrdHIEF expression independently of one another Martin JE,2011 An increase in the expression of nrdH has been observed when CysB is highly overexpressed Liu H,2020. |
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Evidence: | [EXP-IDA-TRANSCRIPT-LEN-DETERMINATION] Length of transcript experimentally determined | ||||||||||
Reference(s): | [1] Jordan A., et al., 1996 | ||||||||||
Promoter | |||||||||||
Name: | nrdHp | ||||||||||
+1: | 2800656 | ||||||||||
Sigma Factor: | Sigma70 Sigmulon | ||||||||||
Distance from start of the gene: | 67 | ||||||||||
Sequence: |
ccactatttgctatatattgtgtggttgaatcttttttcaactacatctagtatctctgtAtcaacagagagacaacccga -35 -10 +1 |
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Note(s): | A σ32-dependent promoter was suggested to be located upstream of nrdH Wade JT,2006, but it is unknown whether this promoter is the same as nrdHp. | ||||||||||
Evidence: |
[COMP-HINF-POSITIONAL-IDENTIFICATION] [EXP-IDA-TRANSCRIPTION-INIT-MAPPING] |
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Reference(s): | [1] Jordan A., et al., 1996 |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence | Confidence level (C: Confirmed, S: Strong, W: Weak) | Reference(s) | |||
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LeftPos | RightPos | Central Rel-Pos | Sequence | ||||||||
proximal | Fur-Fe2+ | repressor | nrdHp | 2800586 | 2800604 | -61.0 | catatccaggGTAATTTCGACCACTATTTgctatatatt | nd | [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-AINF-SIMILAR-TO-CONSENSUS] | W | [2], [3] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence | Confidence level (C: Confirmed, S: Strong, W: Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | ||||||||
nd | IscR | activator | nrdHp | nd | nd | nd | nd | nd | [EXP-IEP-GENE-EXPRESSION-ANALYSIS] | W | [2] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence | Confidence level (C: Confirmed, S: Strong, W: Weak) | Reference(s) | |||
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LeftPos | RightPos | Central Rel-Pos | Sequence | ||||||||
proximal | NrdR-Zn2+ | repressor | nrdHp | 2800603 | 2800618 | -45.5 | cgaccactatTTGCTATATATTGTGTggttgaatct | nd | [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] | W | [4] |
proximal | NrdR-Zn2+ | repressor | nrdHp | 2800634 | 2800649 | -14.5 | aatcttttttCAACTACATCTAGTATctctgtatca | nd | [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] | W | [4] |
RNA cis-regulatory element | ![]() |
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Regulation, transcriptional elongation | |
Attenuator type: | Transcriptional |
Strand: | forward |
Structure type | Energy | LeftPos | RightPos | Sequence (RNA-strand) | |
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terminator | -15.6 | 2800505 | 2800537 | cgcgtctttgACCCCGAAGCCTGTCTTCGGGGTTTCTTTTTGcctggtgaat | |
anti-terminator | -4.7 | 2800470 | 2800512 | atgcgcaaatCGTAGTGCAAAAATGATAATAAATACGCGTCTTTGACCCCGAagcctgtctt | |
anti-anti-terminator | -11.04 | 2800435 | 2800478 | ctgcggtaggTATTTTTATCGGCGCACTGTTAAGCATGCGCAAATCGTAGTGCaaaaatgata |
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos" |
Reference(s) |
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