RegulonDB RegulonDB 10.8: Operon Form
   

cbl operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: cbl
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: cbl
Gene(s): cbl   Genome Browser M3D Gene expression COLOMBOS
Note(s): The transcript of cbl is increased after σE induction, as observed in high-throughput analysis of gene expression Lacoux C,2020.
Evidence: [LTED] Length of transcript experimentally determined
Reference(s): [1] Iwanicka-Nowicka R., et al., 1995
Promoter
Name: cblp
+1: 2060941
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 27
Sequence: tggaataagatgcgggtttttattatttgttatgccgggcattagactttaacaataacgGgaaatctgaactgcccggag
                           -35                     -10      +1                   
Evidence: [HIPP]
[TIM]
Reference(s): [1] Iwanicka-Nowicka R., et al., 1995
TF binding sites (TFBSs)
[CysB,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd CysB-O-acetyl-L-serine activator cblp nd nd nd nd nd [BPP], [GEA] [1]
[NtrC,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd NtrC-Pasp activator cblp nd nd nd nd nd [GEA] [2]


Evidence    

 [HIPP] Human inference of promoter position

 [TIM] Transcription initiation mapping

 [BPP] Binding of purified proteins

 [GEA] Gene expression analysis


Reference(s)    

 [1] Iwanicka-Nowicka R., Hryniewicz MM., 1995, A new gene, cbl, encoding a member of the LysR family of transcriptional regulators belongs to Escherichia coli cys regulon., Gene 166(1):11-7

 [2] Zimmer DP., Soupene E., Lee HL., Wendisch VF., Khodursky AB., Peter BJ., Bender RA., Kustu S., 2000, Nitrogen regulatory protein C-controlled genes of Escherichia coli: scavenging as a defense against nitrogen limitation., Proc Natl Acad Sci U S A 97(26):14674-9

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