![]() ![]() ![]() ![]() |
Name: | osmC |
Gene(s): | osmC Genome Browser M3D Gene expression COLOMBOS |
Evidence: | [AISDTU] Automated inference that a single-gene directon is a transcription unit |
Promoter | |
Name: | osmCp1 |
+1: | 1556596 |
Sigma Factor: | Sigma70 Sigmulon |
Distance from start of the gene: | 29 |
Sequence: |
gccggattttattcggaatatcctgcttatcctcgtgctgtttctcacgtagtctataatTtcctttttaagcccacagga -35 -10 +1 |
Note(s): | The osmCp1 activity is normally independent of σS and it leads to a basal level of expression during exponential phase. osmCp1 and osmCp2 overlap, but they appear to be independent of one another. The two promoters are both growth phase and osmotically regulated. They are sensitive to the action of the global regulators H-NS and Lrp, but the H-NS negative effect on these promoters could be indirect, because there are no putative binding sites of H-NS in the promoter region. |
Evidence: |
[CV(RS-EPT-CBR)] [CV(TIM)] [HIPP] [RS-EPT-CBR] [TIM] |
Reference(s): |
[1] Bouvier J., et al., 1998 [2] Gordia S., et al., 1996 [3] Gutierrez C., et al., 1991 [4] Salgado H, et al., 2012 |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | Lrp1 | repressor | osmCp1 | 1556537 | 1556551 | -52.0 | aatattttcgCCGGATTTTATTCGGaatatcctgc | nd | [APIORCISFBSCS], [BPP], [CV(GEA)], [CV(GEA)], [CV(GEA/SM)], [CV(SM)], [GEA], [SM] | [1] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | NhaR-Na+ | activator | osmCp1 | 1556546 | 1556563 | -42.0 | gccggattttATTCGGAATATCCTGCTTatcctcgtgc | nd | [BCE], [CV(GEA)], [CV(GEA)], [CV(GEA/SM)], [CV(SM)], [GEA], [SM] | [5], [6] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | RcsB-Pasp56 | activator | osmCp1 | 1556548 | 1556561 | -41.5 | cggattttatTCGGAATATCCTGCttatcctcgt | nd | [BPP], [CV(SM)], [GEA], [SM] | [7], [8] |
Note(s): |
1Bouvier J,1998mentioned that they do not know if the inhibitory effect of H-NS on transcription from osmCp1 is direct or indirect. The effect on osmCp1 was independent of σS.1Lrp affected the expression of osmCp1 since it repressed the transcription of osmCp1. This regulator hampers E-sigma S action on osmCp1. Lrp is an important factor in the shift of the effect on the transcription by E-sigma S of osmCp1 (repressor) and osmCp2 (activator) Bouvier J,19981Lrp affected the expression of osmCp1 since it repressed the transcription of osmCp1. This regulator hampers E-sigma S action on osmCp1. Lrp is an important factor in the shift of the effect on the transcription by E-sigma S of osmCp1 (repressor) and osmCp2 (activator) Bouvier J,1998 4Bouvier J,1998mentioned that they do not know if the inhibitory effect of H-NS on transcription from osmCp1 is direct or indirect. The effect on osmCp1 was independent of σS. |
Name: | osmC |
Gene(s): | osmC Genome Browser M3D Gene expression COLOMBOS |
Evidence: | [AISDTU] Automated inference that a single-gene directon is a transcription unit |
Promoter | |
Name: | osmCp2 |
+1: | 1556606 |
Sigma Factor: | Sigma38 Sigmulon |
Distance from start of the gene: | 19 |
Sequence: |
attcggaatatcctgcttatcctcgtgctgtttctcacgtagtctataatttcctttttaAgcccacaggagagcaacaat -35 -10 +1 |
Note(s): | This promoter is induced during the decelerating phase. osmCp1 and osmCp2 overlap, but they appear to be independent of one another. The two promoters are both growth-phase and osmotically regulated. They are sensitive to the action of the global regulators H-NS and Lrp, but the H-NS negative effect on these promoters could be indirect, because there are no putative binding sites of H-NS in the promoter region. |
Evidence: |
[HIPP] [TIM] |
Reference(s): |
[9] Bordes P., et al., 2000 [1] Bouvier J., et al., 1998 [2] Gordia S., et al., 1996 [3] Gutierrez C., et al., 1991 |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | Lrp1 | activator | osmCp2 | 1556537 | 1556551 | -62.0 | aatattttcgCCGGATTTTATTCGGaatatcctgc | nd | [APIORCISFBSCS], [BPP], [CV(GEA)], [CV(GEA)], [CV(GEA/SM)], [CV(SM)], [GEA], [SM] | [1] |
Note(s): |
1When H-NS was absent, transcription from osmCp2 was stimulated but remained totally σS dependent. 1Lrp affected the expression of osmCp2 since it activated the transcription of osmCp2. Lrp is an important factor in the shift of the effect on the transcription by E-sigma S of osmCp1 (repressor) and osmCp2 (activator) Bouvier J,19981Lrp affected the expression of osmCp2 since it activated the transcription of osmCp2. Lrp is an important factor in the shift of the effect on the transcription by E-sigma S of osmCp1 (repressor) and osmCp2 (activator) Bouvier J,1998 2When H-NS was absent, transcription from osmCp2 was stimulated but remained totally σS dependent. |
Reference(s) |
![]() |
---|---|