RegulonDB RegulonDB 10.7: Operon Form
   

gcd operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: gcd
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: gcd
Gene(s): gcd   Genome Browser M3D Gene expression COLOMBOS
Note(s): By making use of micro arrays analysis, Constantinidou et al |CITS: [16377617]| concluded that FNR represses gcd gene expression, but it is not know which of the two promoters ( gcdp1, gcdp2) is affected. They also identified a putative FNR binding site upstream of the gene, but the sequence was not shown.
Evidence: [BTEI] Boundaries of transcription experimentally identified
Reference(s): [1] Yamada M., et al., 1993
Promoter
Name: gcdp1
+1: 141263
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 38
Sequence: atctgttaataaagctcgaattgtgatgacgatcacacatgttaaaacctataattaattGctactaaaatattaatgaat
                          -35                     -10       +1                   
Evidence: [HIPP]
[TIM]
Reference(s): [1] Yamada M., et al., 1993
Terminator(s)
Type: rho-independent
Sequence: tccggcatgaACAACGCGCACGTTGTcagcaatctg
Reference(s): [1] Yamada M., et al., 1993
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CRP-cAMP repressor gcdp1 141284 141305 -31.5 ataaagctcgAATTGTGATGACGATCACACATgttaaaacct nd [APIORCISFBSCS], [BPP], [GEA], [SM] [1], [2]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal IHF activator gcdp1 141330 141342 -73.0 gtataccagtAAAACTATTCATTcgcggaatct nd [APIORCISFBSCS], [GEA], [SM] [2]


Transcription unit       
Name: gcd
Gene(s): gcd   Genome Browser M3D Gene expression COLOMBOS
Note(s): By making use of micro arrays analysis, Constantinidou et al |CITS: [16377617]| concluded that FNR represses gcd gene expression, but it is not know which of the two promoters ( gcdp1, gcdp2) is affected. They also identified a putative FNR binding site upstream of the gene, but the sequence was not shown.
Evidence: [BTEI] Boundaries of transcription experimentally identified
Reference(s): [1] Yamada M., et al., 1993
Promoter
Name: gcdp2
+1: 141279
Distance from start of the gene: 54
Sequence: actattcattcgcggaatctgttaataaagctcgaattgtgatgacgatcacacatgttaAaacctataattaattgctac
Evidence: [TIM]
Reference(s): [1] Yamada M., et al., 1993
Terminator(s)
Type: rho-independent
Sequence: tccggcatgaACAACGCGCACGTTGTcagcaatctg
Reference(s): [1] Yamada M., et al., 1993





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