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Name: | micF |
Gene(s): | micF Genome Browser M3D Gene expression COLOMBOS |
Note(s): | The regulation of micF by Lrp indirectly affects the regulation of ompF (a porin), as micF codes for the antisense RNA that inhibits ompF translation Ferrario M,1995 The expression of the micF gene is affected by antibiotic pressure 17426813 An increase in the micF expression is maintained during exposure to increasing concentrations of the antibiotic tetracycline 17426813 In the same experiment, an increase of micF expression correlated with the expression of the marA gene, which codes for an activator of micF 17426813 Salicylate activates the inaAp and micFp promoters through Rob 22753060 The transcription of the gene micF is enhanced under high oxygen saturation (300%) in the absence of the superoxide dismutase proteins SodA and SodB Baez A,2013 EnvZ-OmpR positively controls MicF RNA under high-osmolarity conditions 7519595 SoxS under oxidative stress 7679383 and MarA in response to antibiotic stress 2848006 The RNA produced by the micF gene has been observed mainly in the poles of the cell during stress conditions 31540875. |
Evidence: | [BTEI] Boundaries of transcription experimentally identified [LTED] Length of transcript experimentally determined |
Reference(s): | [1] Andersen J., et al., 1987 |
Promoter | |
Name: | micFp |
+1: | 2313084 |
Sigma Factor: | Sigma38, Sigma70 |
Distance from start of the gene: | 0 |
Sequence: |
aagtatttgacagcactgaatgtcaaaacaaaaccttcactcgcaactagaataactcccGctatcatcattaactttatt -35 -10 +1 |
Note(s): | The micFp promoter is situated within the micF structural gene, which controls a new species of micF RNA (4.5 S). The micF gene encodes a nontranslated 93-nt antisense RNA (6 S). |
Evidence: |
[HIPP] [TIM] |
Reference(s): |
[1] Andersen J., et al., 1987 [2] Seo SW., et al., 2015 |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | IHF1 | repressor | micFp | 2313006 | 2313018 | -72.0 | tcaaggttaaAATCAATAACTTAttcttaagta | nd | [APIORCISFBSCS], [BCE], [BPP], [CV(GEA)], [CV(GEA)], [GEA] | [11] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | Lrp | repressor | micFp | 2313103 | 2313117 | 27.5 | attaactttaTTTATTACCGTCATTcatttctgaa | nd | [BPP], [GEA] | [8], [15], [16] |
remote | Lrp | repressor | micFp | 2313134 | 2313148 | 58.5 | tgaatgtctgTTTACCCCTATTTCAaccggatgcc | nd | [BPP], [GEA] | [8], [15], [16] |
remote | Lrp | repressor | micFp | 2313163 | 2313177 | 87.5 | gatgcctcgcATTCGGTTTTTTTTAcccttcttta | nd | [BPP], [GEA] | [8], [15], [16] |
remote | Lrp-leucine | repressor | micFp | 2313199 | 2313210 | 122.0 | acacttttcaTTATTCTGTGCTaccacagaaa | nd | [BPP], [GEA] | [8], [16] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | MarA | activator | micFp | 2313034 | 2313053 | -40.0 | aagtatttgaCAGCACTGAATGTCAAAACAaaaccttcac | nd | [AIBSCS], [APIORCISFBSCS], [BPP], [CV(GEA)], [CV(GEA)], [GEA] | [8], [12], [13], [14] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
remote | OmpR-P | activator | micFp | 2312868 | 2312887 | -206.5 | atccaacacgAATATGATACTAAAACTTTTaagatgtttc | nd | [APIORCISFBSCS], [BPP], [CV(GEA)], [CV(GEA)], [CV(GEA/SM)], [CV(SM)], [GEA], [SM] | [3], [4], [5], [6] |
remote | OmpR-P | activator | micFp | 2312888 | 2312907 | -186.5 | taaaacttttAAGATGTTTCATTTATCGCTatagatgttt | nd | [APIORCISFBSCS], [BPP], [CV(GEA)], [CV(GEA)], [CV(GEA/SM)], [CV(SM)], [GEA], [SM] | [3], [4], [6], [7] |
remote | OmpR-P | activator | micFp | 2312909 | 2312928 | -165.5 | tttatcgctaTAGATGTTTCAAAATGTAAAtgcaagggaa | nd | [APIORCISFBSCS], [BPP], [CV(GEA)], [CV(GEA)], [CV(GEA/SM)], [CV(SM)], [GEA], [SM] | [3], [4], [6], [7] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | Rob | activator | micFp | 2313034 | 2313053 | -40.0 | aagtatttgaCAGCACTGAATGTCAAAACAaaaccttcac | nd | [APIORCISFBSCS], [BPP], [CV(GEA)], [CV(GEA)], [GEA] | [12] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
remote | SoxS | activator | micFp | 2312955 | 2312974 | -119.5 | aagattattgCGGAATGGCGAAATAAGCACctaacatcaa | nd | [BCE], [BPP], , [IHBCE], | [8], [9], [10] |
proximal | SoxS | activator | micFp | 2313036 | 2313055 | -38.5 | gtatttgacaGCACTGAATGTCAAAACAAAaccttcactc | nd | [BCE], [BPP], , [IHBCE], | [8], [9], [10] |
Note(s): |
1The regulatory effect of IHF on the promoter micFp1 is not yet known. However, we have assigned a negative effect to this regulatory interaction based on the fact that the protein's binding site overlaps the transcription start site of the promoter.5The regulatory effect of IHF on the promoter micFp1 is not yet known. However, we have assigned a negative effect to this regulatory interaction based on the fact that the protein's binding site overlaps the transcription start site of the promoter. |
Reference(s) |
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