RegulonDB RegulonDB 10.9: Operon Form
   

rtcBA operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: rtcBA
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: rtcBA
Gene(s): rtcA, rtcB   Genome Browser M3D Gene expression COLOMBOS
Evidence: [PM] Polar mutation
Reference(s): [1] Genschik P., et al., 1998
Promoter
Name: rtcBp
+1: 3558107
Sigma Factor: Sigma54 Sigmulon
Distance from start of the gene: 28
Sequence: tgaattaaaaaattaagctgcttatttaattttctggcacgacggttgcaattatcaggaCagcaaacaacgaaaagagaa
                                   -24         -12          +1                   
Evidence: [HIPP]
[ICWHO]
[TIM]
Reference(s): [1] Genschik P., et al., 1998
[2] Huerta AM., et al., 2003
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal IHF1 activator rtcBp 3558153 3558165 -52.0 ttaaaacaatGAATTAAAAAATTAagctgcttat nd [AIBSCS] [1]
proximal IHF2 activator rtcBp 3558163 3558175 -62.0 ataatcttttTTAAAACAATGAATtaaaaaatta nd [AIBSCS] [1]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd RtcR1 activator rtcBp nd nd nd nd nd [BPP], [GEA], [IGI] [1]
Note(s): 1The regulatory effect of IHF on the rtcB promoter is as yet not known. However, we assigned a positive effect to this regulatory interaction based on the protein's binding site being upstream of the promoter (52 bp upstream of the transcription start site).
2The regulatory effect of IHF on the rtcB promoter is not yet known. However, we assigned a positive effect to this regulatory interaction based on the protein's binding site, which is upstream of the promoter (62 bp upstream of the transcription start site).1RtcR with its N terminal truncated activates the transcription of the rtcBA operon.1The regulatory effect of IHF on the rtcB promoter is not yet known. However, we assigned a positive effect to this regulatory interaction based on the protein's binding site, which is upstream of the promoter (62 bp upstream of the transcription start site).
2The regulatory effect of IHF on the rtcB promoter is as yet not known. However, we assigned a positive effect to this regulatory interaction based on the protein's binding site being upstream of the promoter (52 bp upstream of the transcription start site).
3RtcR with its N terminal truncated activates the transcription of the rtcBA operon.





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