RegulonDB RegulonDB 10.8: Operon Form
   

nac operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: nac
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: nac
Gene(s): nac   Genome Browser M3D Gene expression COLOMBOS
Note(s): The transcription of the nac gene is induced under nitrogen-limiting conditions Camarena L,1998.
Under nitrogen-rich growth conditions, the expression of the nac gene was increased in mutants for two genes that encode two terminal oxidases, cyoA and cydB, and in mutants for two transcriptional regulators, Fnr and Fur Kumar R,2011
Evidence: [LTED] Length of transcript experimentally determined
Reference(s): [1] Camarena L., et al., 1998
Promoter
Name: nacp
+1: 2061978
Sigma Factor: Sigma54 Sigmulon
Distance from start of the gene: 45
Sequence: ttggttagcttgtacatcaacaccaaaataaaactggcaagcatcttgcaatctggttgtAagtaatggcggcacttgggc
                                   -24         -12          +1                   
Evidence: [HIPP]
[TIM]
Reference(s): [2] Muse WB., et al., 1998
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd FNR repressor nacp nd nd nd nd nd [GEA] [3]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd Fur-Fe2+ repressor nacp nd nd nd nd nd [GEA] [3]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal Nac repressor nacp 2062046 2062060 -75.0 tgacgaatctATCATAATCTCTTATttgacagttg nd [APIORCISFBSCS], [BPP], [CV(GEA)], [CV(GEA)], [GEA] [2]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote NtrC-Pasp activator nacp 2062122 2062138 -152.0 tattgggtaaTGAACCATCGTGGTGCAtaccctcctt nd [APIORCISFBSCS] [2]





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