RegulonDB RegulonDB 11.0: Operon Form

zraP operon and associated TUs in Escherichia coli K-12 genome

Name: zraP
This page displays every known transcription unit of this operon and their known regulation.

Transcription unit          
Name: zraP
Gene(s): zraP   Genome Browser M3D Gene expression COLOMBOS
Note(s): The transcription of zraP is induced by high concentrations of zinc Ravikumar S, Yoo IK, Lee SY, Hong SH,2011.
Reference(s): [1] Leonhartsberger S., et al., 2001
Name: zraPp
+1: 4201712
Sigma Factor: Sigma54 Sigmulon
Distance from start of the gene: 24
Sequence: gccagattacccgtcatatcagcgtttcatcgttggcacggaagatgcaatacccgaagtAagacaaccactggaggatta
                                  -24         -12           +1                   
Note(s): We assigned a putative transcription start site to this promoter based on the observation that the majority of the σ54-dependent promoters, whose transcription start sites were determined experimentally, present a distance of 11 nucleotides between the transcription start site and the -12 box Barrios H,1999.
Evidence: [AIBSCS]
Reference(s): [2] Huerta AM., et al., 2003
[1] Leonhartsberger S., et al., 2001
[3] Reitzer L., et al., 2001
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal ZraR-phosphorylated activator zraPp 4201782 4201798 -78.0 cccgcagcagGCGAGTCATTTTTACTCgtttatcatg nd [GEA], [APIORCISFBSCS], [BPP], [CSEUMA] [1], [4]
remote ZraR-phosphorylated activator zraPp 4201811 4201827 -107.0 aagtttcaatGAGTAAAAATGACTCGCtacccgcagc nd [GEA], [BPP], [CSEUMA] [1], [4]