RegulonDB RegulonDB 10.6.3: Operon Form
   

zraP operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: zraP
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: zraP
Gene(s): zraP   Genome Browser M3D Gene expression COLOMBOS
Note(s): The transcription of zraP is induced by high concentrations of zinc |CITS:[21674266]|.
Reference(s): [1] Leonhartsberger S., et al., 2001
Promoter
Name: zraPp
+1: 4201712
Sigma Factor: Sigma54 Sigmulon
Distance from start of the gene: 24
Sequence: gccagattacccgtcatatcagcgtttcatcgttggcacggaagatgcaatacccgaagtAagacaaccactggaggatta
                                  -12         -24           +1                   
Note(s): We assigned a putative transcription start site to this promoter based on the observation that the majority of the σ54-dependent promoters, whose transcription start sites were determined experimentally, present a distance of 11 nucleotides between the transcription start site and the -12 box Barrios H,1999.
Evidence: [AIPP]
[HIPP]
Reference(s): [1] Leonhartsberger S., et al., 2001
[2] Reitzer L., et al., 2001
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal ZraR-Phosphorylated activator zraPp 4201782 4201798 -78.0 cccgcagcagGCGAGTCATTTTTACTCgtttatcatg nd [BPP], [GEA], [HIBSCS] [1]
remote ZraR-Phosphorylated2 activator zraPp 4201811 4201827 -107.0 aagtttcaatGAGTAAAAATGACTCGCtacccgcagc nd [BPP], [GEA] [1]
Note(s): 2ZraR activates the zraPp promoter in the presence of high Zn2+ and Pb2+ concentrations Leonhartsberger S,2001.1ZraR activates the zraPp promoter in the presence of high Zn2+ and Pb2+ concentrations Leonhartsberger S,2001.





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