RegulonDB RegulonDB 11.2: Operon Form

zraSR operon and associated TUs in Escherichia coli K-12 genome

Name: zraSR
This page displays every known transcription unit of this operon and their known regulation.

Transcription unit          
Name: zraSR
Synonym(s): hydHG
Gene(s): zraS, zraR   Genome Browser M3D Gene expression COLOMBOS
Evidence: [EXP-IEP] Inferred from expression pattern
[EXP-IEP-COREGULATION] Inferred through co-regulation
Reference(s): [1] Stoker K., et al., 1989
Name: zraSp
+1: 4201905
Sigma Factor: Sigma54 Sigmulon
Distance from start of the gene: 21
Sequence: tgtgttacagcgcagggtaagcgctgataaaagatggcatgatttctgctgtcagaaaggGatgagcaggcaaagaagaag
                                   -24         -12          +1                   
Note(s): We assigned a putative transcription start site to this promoter based on the observation that the majority of the σ54-dependent promoters, whose transcription start sites were determined experimentally, present a distance of 11 nucleotides between the transcription start site and the -12 box Barrios H,1999.
Evidence: [COMP-AINF]
Reference(s): [2] Huerta AM., et al., 2003
[3] Leonhartsberger S., et al., 2001
[4] Reitzer L., et al., 2001
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote CRP-cyclic-AMP activator zraSp 4201671 4201692 -223.5 ccagggcaatTTTCGTGTTCCGTTTCATGGTTaatcctccag nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-AINF-SIMILAR-TO-CONSENSUS] W [5]

RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Transcriptional
Strand: forward
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -14.5 4201791 4201824 gagtaaaaatGACTCGCCTGCTGCGGGTAGCGAGTCATTTTTActcattgaaa
  anti-terminator -5.3 4201770 4201803 gggtaatctgGCATGATAAACGAGTAAAAATGACTCGCCTGCTgcgggtagcg
  anti-anti-terminator -11.8 4201733 4201775 tgcatcttccGTGCCAACGATGAAACGCTGATATGACGGGTAATCTGGCATGataaacgagt
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"