|
|
| Operon |  |
|---|---|
| Name: | rsd |
| This page displays every known transcription unit of this operon and their known regulation. | |
| Name: | rsd |
| Gene(s): | rsd Genome Browser M3D Gene expression COLOMBOS |
| Note(s): | Based on analysis using a promoter-specific transcription factor screening system (PS-TF), it has been shown that the rsd and rmf promoters are repressed by ArcA and activated by McbR, RcdA, SdiA, and SlyA transcription factors (TFs) during the transition from exponential to stationary growth phase. On the other hand, a total of 11 TFs (CueR, DmlR, GlpR, QseF, OmpR, UxuR, BtsR, YfeR, YhaJ, YiuA, and YijO) were estimated to bind to the rmf promoter Yoshida H,2018 The SlyA-binding site could be overlapping the ArcA-binding site in rsd in the upstream region of the promoter. For the other three TFs (McbR, RcdA, and SdiA), their wide binding sequences are between approximately bp -100 and -200 for McbR, between -120 and -220 for RcdA, and between -50 and -280 for SdiA upstream of the start of the gene Yoshida H,2018 The TFs are controlled by specific effector ligands which decrease in the presence of the corresponding effector, such as AcP for ArcA and AI-1 for SdiA, and increase in its presence, such as AI-2 for McbR, acetate for RcdA, and ppGpp for SlyA Yoshida H,2018 |
| Evidence: | [ICWHO] Inferred computationally without human oversight |
| Promoter | |
| Name: | rsdp2 |
| +1: | 4196859 |
| Sigma Factor: | Sigma70 Sigmulon |
| Distance from start of the gene: | 51 |
| Sequence: |
tcaattatacgatccatagctcttgcactacctttgcatcactggcatgtttaacatggtTtttacatttctcactgagca -35 -10 +1 |
| Evidence: |
[HIPP] [ICWHO] [IHBCE] [IPI] [TIM] |
| Reference(s): |
[1] Huerta AM., et al., 2003 [2] Jishage M., et al., 1999 [3] Yoshida H., et al., 2018 |
| Name: | rsd |
| Gene(s): | rsd Genome Browser M3D Gene expression COLOMBOS |
| Evidence: | [ICWHO] Inferred computationally without human oversight |
| Promoter | |
| Name: | rsdp1 |
| +1: | 4196954 |
| Sigma Factor: | Sigma38 Sigmulon |
| Distance from start of the gene: | 146 |
| Sequence: |
gatcgaaatttgccgcttcgccatatggcaattctcccttcggcaaccataatttttgttCatggctgacgacccaccagc -35 -10 +1 |
| Evidence: |
[HIPP] [ICWHO] [IHBCE] [IMP] [TIM] |
| Reference(s): |
[1] Huerta AM., et al., 2003 [2] Jishage M., et al., 1999 |
| Reference(s) |
|
|---|---|
[HIPP] Human inference of promoter position