RegulonDB RegulonDB 11.1: Operon Form
   

thrW operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: thrW
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: thrW
Gene(s): thrW   Genome Browser M3D Gene expression COLOMBOS
Evidence: [EXP-IDA-BOUNDARIES-DEFINED] Boundaries of transcription experimentally identified
Promoter
Name: thrWp
+1: 262841
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 30
Sequence: gccatttgattcacaaggccattgacgcatcgcccggttagttttaaccttgtccaccgtGattcacgttcgtgaacatgt
                      -35                    -10            +1                   
Evidence: [COMP-AINF]
[COMP-HINF-POSITIONAL-IDENTIFICATION]
Reference(s): [1] Huerta AM., et al., 2003
TF binding sites (TFBSs)
[Fis,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal Fis activator thrWp 262768 262782 -66.0 taaaaccgggTGATGCAAAAGTAGCcatttgattc nd [EXP-IDA-BINDING-OF-CELLULAR-EXTRACTS] nd nd


Evidence    

 [COMP-AINF] Inferred computationally without human oversight

 [COMP-HINF-POSITIONAL-IDENTIFICATION] Human inference of promoter position

 [EXP-IDA-BINDING-OF-CELLULAR-EXTRACTS] Binding of cellular extracts


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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