RegulonDB RegulonDB 10.10: Operon Form
   

proK operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: proK
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: proK
Gene(s): proK   Genome Browser M3D Gene expression COLOMBOS
Evidence: [BTEI] Boundaries of transcription experimentally identified
Promoter
Name: proKp
+1: 3708694
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 2
Sequence: aggcattttgctattaagggattgacgagggcgtatctgcgcagtaagatgcgccccgcaTtcggtgattggcgcagcctg
                      -35                    -10            +1                   
Evidence: [HIPP]
[ICWHO]
Reference(s): [1] Huerta AM., et al., 2003
Terminator(s)
Type: rho-independent
Sequence: tgagctgcagATGCAAAAAAGCCTGCTCGTTGAGCAGGCTTTTCGAATTtggtcggtga
Reference(s): [2] Peters JM., et al., 2009
[3] Zuker M. 2003
Type: rho-independent
Sequence: tgagctgcagATGCAAAAAAGCCTGCTCGTTGAGCAGGCTTTTCGAATTtggtcggtga
Reference(s): [2] Peters JM., et al., 2009
[3] Zuker M. 2003
TF binding sites (TFBSs)
[Fis,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal Fis activator proKp 3708763 3708777 -76.0 ctaagcggccTGCTGACTTTCTCGCcgatcaaaag nd [BCE] nd


Evidence    

 [HIPP] Human inference of promoter position

 [ICWHO] Inferred computationally without human oversight

 [BCE] Binding of cellular extracts


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Peters JM., Mooney RA., Kuan PF., Rowland JL., Keles S., Landick R., 2009, Rho directs widespread termination of intragenic and stable RNA transcription., Proc Natl Acad Sci U S A 106(36):15406-11

 [3] Zuker M., 2003, Mfold web server for nucleic acid folding and hybridization prediction., Nucleic Acids Res 31(13):3406-15

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