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Name: | fixABCX | ||||||||||
Gene(s): | fixA, fixB, fixC, fixX Genome Browser M3D Gene expression COLOMBOS | ||||||||||
Note(s): | On the basis of studies of L-carnitine metabolism and the development of a biosensor, it was determined that crotonobetainyl-CoA is the sought-after coactivator of CaiF in the fixAp promoter Kugler P, Fröhlich D, Wendisch VF,2020 | ||||||||||
Evidence: | [EXP-IDA-TRANSCRIPT-LEN-DETERMINATION] Length of transcript experimentally determined | ||||||||||
Reference(s): | [1] Eichler K., et al., 1995 | ||||||||||
Promoter | |||||||||||
Name: | fixAp | ||||||||||
+1: | 42325 | ||||||||||
Sigma Factor: | Sigma70 Sigmulon | ||||||||||
Distance from start of the gene: | 78 | ||||||||||
Sequence: |
tattgaaagttggatttatctgcgtgtgacattttcaatattggtgattaaagttttattTcaaaattaaagggcgtgata -35 -10 +1 |
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Evidence: |
[COMP-AINF] [COMP-HINF] [COMP-HINF-POSITIONAL-IDENTIFICATION] [EXP-IDA-TRANSCRIPTION-INIT-MAPPING] |
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Reference(s): |
[2] Eichler K., et al., 1996 [3] Huerta AM., et al., 2003 |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence | Confidence level (C: Confirmed, S: Strong, W: Weak) | Reference(s) | |||
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LeftPos | RightPos | Central Rel-Pos | Sequence | ||||||||
remote | CRP-cyclic-AMP | activator | fixAp | 42188 | 42209 | -126.5 | gactttcaatATTGGTGATCCATAAAACAATAttgaaaattt | nd | [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS] | W | [2], [6], [7] |
proximal | CRP-cyclic-AMP | activator | fixAp | 42245 | 42266 | -69.5 | tgttttcaatATTGGTGAGGAACTTAACAATAttgaaagttg | nd | [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS] | W | [2], [6], [7] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence | Confidence level (C: Confirmed, S: Strong, W: Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | ||||||||
remote | FNR | activator | fixAp | 42121 | 42134 | -197.5 | cgttttttcgTTAATTTTGATTAAtaatcagttt | nd | [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-AINF-SIMILAR-TO-CONSENSUS] | W | [4], [5] |
RNA cis-regulatory element | ![]() |
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Regulation, transcriptional elongation | |
Attenuator type: | Translational |
Strand: | forward |
Structure type | Energy | LeftPos | RightPos | Sequence (RNA-strand) | |
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terminator | -19.2 | 44134 | 44174 | gttgatccacTCTGGCAGGGCTGCATTTTGGCCCTGCCGCTGACAGGGAGctcttatgtc |
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos" |
Reference(s) |
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