RegulonDB RegulonDB 11.1: Operon Form
   

msrA operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: msrA
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: msrA
Gene(s): msrA   Genome Browser M3D Gene expression COLOMBOS
Evidence: [EXP-IDA-TRANSCRIPT-LEN-DETERMINATION] Length of transcript experimentally determined
Reference(s): [1] Moskovitz J., et al., 1995
Promoter
Name: msrAp
+1: 4442261
Distance from start of the gene: 85
Sequence: atccagtaatatggattaaaaagcagactaaaccccaaatatttcttatgttttactttaGacctattcacggtggttatt
Evidence: [EXP-IDA-TRANSCRIPTION-INIT-MAPPING]
Reference(s): [1] Moskovitz J., et al., 1995
TF binding sites (TFBSs)
[Fis,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal Fis repressor msrAp 4442256 4442275 -4.0 aaatatttctTATGTTTTACTTTAGACCTAttcacggtgg nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-AINF-SIMILAR-TO-CONSENSUS] W [2]
proximal Fis repressor msrAp 4442292 4442311 -40.0 atccagtaatATGGATTAAAAAGCAGACTAaaccccaaat nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-AINF-SIMILAR-TO-CONSENSUS] W [2]


Evidence    

 [EXP-IDA-TRANSCRIPTION-INIT-MAPPING] Transcription initiation mapping

 [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis

 [COMP-AINF-SIMILAR-TO-CONSENSUS] Automated inference based on similarity to consensus sequences


Reference(s)    

 [1] Moskovitz J., Rahman MA., Strassman J., Yancey SO., Kushner SR., Brot N., Weissbach H., 1995, Escherichia coli peptide methionine sulfoxide reductase gene: regulation of expression and role in protecting against oxidative damage., J Bacteriol 177(3):502-7

 [2] Bradley MD., Beach MB., de Koning AP., Pratt TS., Osuna R., 2007, Effects of Fis on Escherichia coli gene expression during different growth stages., Microbiology 153(Pt 9):2922-40

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