RegulonDB RegulonDB 10.6.3: Operon Form

ampC operon and associated TUs in Escherichia coli K-12 genome

Name: ampC
This page displays every known transcription unit of this operon and their known regulation.

Transcription unit          
Name: ampC
Gene(s): ampC   Genome Browser M3D Gene expression COLOMBOS
Note(s): A transcriptional attenuator sequence that regulates the ampC gene expression was identified downstream of the ampCp promoter |CITS:[7010184], [17326753]|.
Evidence: [BTEI] Boundaries of transcription experimentally identified
Reference(s): [1] Bishop RE., et al., 1995
[2] Jaurin B., et al., 1981
[3] Jaurin B., et al., 1982
Name: ampCp
+1: 4379003
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 59
Sequence: tacggtctggctgctatcctgacagttgtcacgctgattggtgtcgttacaatctaacgcAtcgccaatgtaaatccggcc
                          -10                   -35         +1                   
Evidence: [IMP]
Reference(s): [2] Jaurin B., et al., 1981
[3] Jaurin B., et al., 1982
[4] Salgado H, et al., 2012
Type: rho-independent
Sequence: gcggagaaaaGGTCCGAAAATTCGGACCcgatggaatt
Reference(s): [1] Bishop RE., et al., 1995
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd BolA dual ampCp nd nd nd nd nd [GEA], [IMP] [5]
nd BolA dual ampCp nd nd nd nd nd [GEA], [IMP] [5]

RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Transcriptional
Strand: reverse
Evidence: [ICA] Inferred by computational analysis
Reference(s): [6] null null
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -19.1 4378961 4378987 aatgtaaatcCGGCCCGCCTATGGCGGGCCGTTTTGtatggaaacc
  anti-terminator -12.51 4378984 4379031 cagttgtcacGCTGATTGGTGTCGTTACAATCTAACGCATCGCCAATGTAAATCCGGcccgcctatg
  anti-anti-terminator -8.6 4379028 4379061 gggttttctaCGGTCTGGCTGCTATCCTGACAGTTGTCACGCTgattggtgtc
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"