RegulonDB RegulonDB 10.10: Operon Form
   

tauABCD operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: tauABCD
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: tauABCD
Gene(s): tauA, tauB, tauC, tauD   Genome Browser M3D Gene expression COLOMBOS
Note(s): The mRNA produced by the tauABCD operon has been observed mainly in the cellular membrane Kannaiah S, Livny J, Amster-Choder O,2019.
The transcription of the tauA gene is induced during the first 24 h after the induction of nitrogen starvation Switzer A, Burchell L, McQuail J, Wigneshweraraj S,2020.
Evidence: [BTEI] Boundaries of transcription experimentally identified
[PM] Polar mutation
Reference(s): [1] Kwon O., et al., 2005
[2] van der Ploeg JR., et al., 1996
Promoter
Name: tauAp
+1: 385205
Distance from start of the gene: 27
Sequence: tcatctgtgcgataacgactaattcttttaatgaatgtttttattcctgaatactgctccCataacaagacaggggagcag
Evidence: [TIM]
Reference(s): [2] van der Ploeg JR., et al., 1996
TF binding sites (TFBSs)
[Cbl,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal Cbl activator tauAp 385094 385133 -91.0 gttagaacggAGTAATTGCATATTTAATCTTTCCTTAGCCGTTTTTTTGCtaagaataaa nd [GEA], [BPP] [3]
[CysB,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote CysB-O-acetyl-L-serine activator tauAp 384982 385023 -202.0 aatataatagTTTTATTATATGTATTGATATTGATAGAAATAATGAAGTAATaaatctcgta nd [GEA], [BPP] [3]
remote CysB-O-acetyl-L-serine activator tauAp 385091 385132 -93.0 attgttagaaCGGAGTAATTGCATATTTAATCTTTCCTTAGCCGTTTTTTTGctaagaataa nd [GEA], [BPP] [3]
proximal CysB-O-acetyl-L-serine activator tauAp 385146 385187 -38.0 agaataaaatCATCTGTGCGATAACGACTAATTCTTTTAATGAATGTTTTTAttcctgaata nd [GEA], [BPP] [3]


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Translational
Strand: forward
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -14.0 385192 385232 ttttattcctGAATACTGCTCCCATAACAAGACAGGGGAGCAGACAATCAtggcaatttc
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"


Evidence    

 [TIM] Transcription initiation mapping

 [GEA] Gene expression analysis

 [BPP] Binding of purified proteins


Reference(s)    

 [1] Kwon O., Druce-Hoffman M., Meganathan R., 2005, Regulation of the ubiquinone (coenzyme Q) biosynthetic genes ubiCA in Escherichia coli., Curr Microbiol 50(4):180-9

 [2] van der Ploeg JR., Weiss MA., Saller E., Nashimoto H., Saito N., Kertesz MA., Leisinger T., 1996, Identification of sulfate starvation-regulated genes in Escherichia coli: a gene cluster involved in the utilization of taurine as a sulfur source., J Bacteriol 178(18):5438-46

 [3] van der Ploeg JR., Iwanicka-Nowicka R., Kertesz MA., Leisinger T., Hryniewicz MM., 1997, Involvement of CysB and Cbl regulatory proteins in expression of the tauABCD operon and other sulfate starvation-inducible genes in Escherichia coli., J Bacteriol 179(24):7671-8

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