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Name: | ruvAB |
Gene(s): | ruvB, ruvA Genome Browser M3D Gene expression COLOMBOS |
Evidence: | [BTEI] Boundaries of transcription experimentally identified |
Reference(s): |
[1] Benson FE., et al., 1988 [2] Iwasaki H., et al., 1989 [3] Shinagawa H., et al., 1988 |
Promoter | |
Name: | ruvAp2 |
+1: | 1946016 |
Distance from start of the gene: | 40 |
Sequence: |
tcgagacacctcgcaagttttcttcatccttcgctggatatctatccagcatttttttatCatacagcattatctttgatt |
Evidence: | [TIM] |
Reference(s): | [3] Shinagawa H., et al., 1988 |
Terminator(s) | |
Type: | rho-independent |
Sequence: | ctctggtagtCCTGGTAAGACGCGAACAGCGTCGCATCAGGcatattgcca |
Reference(s): | [3] Shinagawa H., et al., 1988 |
Type: | rho-independent |
Sequence: | gaacacatttGTCGGATGCGGCGCGAGCGCCTTATCCGACctacggttcg |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | LexA | repressor | ruvAp2 | 1946026 | 1946045 | -19.5 | cttcatccttCGCTGGATATCTATCCAGCAtttttttatc | nd | [APIORCISFBSCS], [BPP] | [1], [3], [4], [5] |
proximal | LexA | repressor | ruvAp2 | 1946079 | 1946098 | -72.5 | gaataaattaTACTGTGCCATTTTTCAGTTcatcgagaca | nd | [APIORCISFBSCS] | [1], [4] |
Name: | ruvAB |
Gene(s): | ruvB, ruvA Genome Browser M3D Gene expression COLOMBOS |
Note(s): | Based on the bacteriostatic antibiotic-induced persister model, 37 and 9 genes were found to produce defects in rifampin- and tetracycline-induced persister formation, respectively. Only six mutants were found to overlap in both treatment-induced persister screens: recA, recC, ruvA, uvrD, fis, and acrB. Four of these mutants (recA, recC, ruvA, and uvrD) mapped to the DNA repair pathway, one mutant mapped to a global transcriptional regulator (fis), and one to a gene for an efflux protein (acrB) 29559967 Other genes that mapped to transporters, membrane biogenesis, LPS biosynthesis, flagellum biosynthesis, metabolism (folate and energy), and translation were more specific to rifampin-induced persisters 29559967 |
Evidence: | [BTEI] Boundaries of transcription experimentally identified |
Reference(s): |
[1] Benson FE., et al., 1988 [2] Iwasaki H., et al., 1989 [3] Shinagawa H., et al., 1988 |
Promoter | |
Name: | ruvAp1 |
+1: | 1946024 |
Distance from start of the gene: | 48 |
Sequence: |
tcagttcatcgagacacctcgcaagttttcttcatccttcgctggatatctatccagcatTtttttatcatacagcattat |
Evidence: | [TIM] |
Reference(s): | [3] Shinagawa H., et al., 1988 |
Terminator(s) | |
Type: | rho-independent |
Sequence: | ctctggtagtCCTGGTAAGACGCGAACAGCGTCGCATCAGGcatattgcca |
Reference(s): | [3] Shinagawa H., et al., 1988 |
Type: | rho-independent |
Sequence: | gaacacatttGTCGGATGCGGCGCGAGCGCCTTATCCGACctacggttcg |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | LexA | repressor | ruvAp1 | 1946027 | 1946046 | -12.5 | tcttcatcctTCGCTGGATATCTATCCAGCatttttttat | nd | [APIORCISFBSCS], [BPP] | [1], [3], [4], [5] |
proximal | LexA | repressor | ruvAp1 | 1946078 | 1946097 | -63.5 | aataaattatACTGTGCCATTTTTCAGTTCatcgagacac | nd | [APIORCISFBSCS] | [1], [4] |
Reference(s) |
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