RegulonDB RegulonDB 10.7: Operon Form
   

tonB operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: tonB
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: tonB
Synonym(s): OP00228
Gene(s): tonB   Genome Browser M3D Gene expression COLOMBOS
Evidence: [BTEI] Boundaries of transcription experimentally identified
[LTED] Length of transcript experimentally determined
Reference(s): [1] Postle K., et al., 1983
[2] Young GM., et al., 1994
Promoter
Name: tonBp
+1: 1311054
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 35
Sequence: ttcactgatcctgatcgtcttgccttattgaatatgattgctatttgcatttaaaatcgaGacctggtttttctactgaaa
                            -35                     -10     +1                   
Evidence: [TIM]
Reference(s): [3] Lisser S., et al., 1993
[1] Postle K., et al., 1983
Terminator(s)
Type: rho-independent
Sequence: gtaagcagaaAGTCAAAAGCCTCCGACCGGAGGCTTTTGACTattactcaac
Reference(s): [1] Postle K., et al., 1983
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal Fur-Fe2+ activator tonBp 1311020 1311038 -25.0 gtcttgccttATTGAATATGATTGCTATTtgcatttaaa nd [AIBSCS], [APIORCISFBSCS], [BPP] [2], [4], [5]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal Fur-Fe2+1 repressor tonBp 1311026 1311044 -19.0 ccttattgaaTATGATTGCTATTTGCATTtaaaatcgag nd [APIORCISFBSCS], [BCE], [BPP] [2], [4], [5]
proximal Fur-Fe2+ repressor tonBp 1311030 1311048 -15.0 attgaatatgATTGCTATTTGCATTTAAAatcgagacct nd [APIORCISFBSCS], [BPP] [4]
proximal Fur-Fe2+ repressor tonBp 1311070 1311088 26.0 gtttttctacTGAAATGATTATGACTTCAatgacccttg nd [BCE] [2]
Note(s): 1Fur binds DNA at a site between the -10 and -35 regions of the tonB promoter under aerobic and anaerobic conditions, but only when iron is present in excess .
2Fur binds DNA at a site between the -10 and -35 regions of the tonB promoter under aerobic and anaerobic conditions, but only when iron is present in excess .





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