RegulonDB RegulonDB 10.10: Operon Form
   

glpFKX operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: glpFKX
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: glpFKX
Synonym(s): OP00237
Gene(s): glpX, glpK, glpF   Genome Browser M3D Gene expression COLOMBOS
Note(s): The first documented case of transposon-mediated directed mutagenesis has been determined for the glpFKX promoter region, where CRP acts as activator and GlpR as repressor Zhang Z, Saier MH,2011
Evidence: [BTEI] Boundaries of transcription experimentally identified
[PM] Polar mutation
Reference(s): [1] Lupski JR., et al., 1990
[2] Truniger V., et al., 1992
[3] Weissenborn DL., et al., 1992
Promoter
Name: glpFp
+1: 4118161
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 71
Sequence: ggcacacacattttaagttcgatatttctcgtttttgctcgttaacgataagtttacagcAtgcctacaagcatcgtggag
                          -35                    -10        +1                   
Evidence: [HIPP]
[ICWHO]
[TIM]
Reference(s): [4] Huerta AM., et al., 2003
[3] Weissenborn DL., et al., 1992
Terminator(s)
Type: rho-independent
Sequence: aacaaaaaaaTTCCAGTCCCGAAGGACTGGAAggctcaatcg
Reference(s): [2] Truniger V., et al., 1992
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CRP-cyclic-AMP activator glpFp 4118188 4118209 -37.5 cacacacattTTAAGTTCGATATTTCTCGTTTttgctcgtta nd [GEA], [APIORCISFBSCS] [3]
proximal CRP-cyclic-AMP activator glpFp 4118211 4118232 -60.5 ataacgctcaTTTTATGACGAGGCACACACATtttaagttcg nd [GEA], [APIORCISFBSCS] [3]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote GlpR repressor glpFp 4117109 4117128 1043.5 attagcgtgtCGCAGCGCGAATTTGAGCAAatctacccaa nd [APIORCISFBSCS], [BPP] [3]
remote GlpR repressor glpFp 4117151 4117170 1001.5 accagctcccGCGCGGTCGTAATGGATCACgatgccaata nd [APIORCISFBSCS], [BPP] [3]
proximal GlpR repressor glpFp 4118169 4118188 -17.5 atttctcgttTTTGCTCGTTAACGATAAGTttacagcatg nd [APIORCISFBSCS], [BPP] [3]
proximal GlpR repressor glpFp 4118189 4118208 -37.5 acacacatttTAAGTTCGATATTTCTCGTTtttgctcgtt nd [APIORCISFBSCS], [BPP] [3]
proximal GlpR repressor glpFp 4118210 4118229 -58.5 acgctcatttTATGACGAGGCACACACATTttaagttcga nd [APIORCISFBSCS], [BPP] [3]
proximal GlpR repressor glpFp 4118231 4118250 -79.5 gatggaataaATGGCGCGATAACGCTCATTttatgacgag nd [APIORCISFBSCS], [BPP] [3]





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