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| Operon |  |
|---|---|
| Name: | wza-wzb-wzc-wcaAB |
| This page displays every known transcription unit of this operon and their known regulation. | |
| Name: | wzbc |
| Gene(s): | wzc, wzb, wza Genome Browser M3D Gene expression COLOMBOS |
| Note(s): | The expression of this operon is increased when colicin (at 30 ng/ml) is added to the medium Kamen?ek S, ?gur-Bertok D,2013. |
| Evidence: | [ITCR] Inferred through co-regulation |
| Reference(s): | [1] Rhodius VA., et al., 2005 |
| Promoter | |
| Name: | wzap2 |
| +1: | 2137193 |
| Sigma Factor: | Sigma24 Sigmulon |
| Distance from start of the gene: | -50 |
| Sequence: |
taaataaacaatgatgaaatccaaaatgaaattgatgccattattggtgtcagtaaccttGataagcggttgcacagtact |
| Note(s): | The wza gene may have been misannotated, because the transcription start site of wzap2 is 50 bp downstream of the start site of the gene Rhodius VA,2005 |
| Evidence: |
[AIBSCS] [AIPP] [TIM] |
| Reference(s): | [1] Rhodius VA., et al., 2005 |
| Name: | wza-wzb-wzc-wcaAB | |||||||||
| Synonym(s): | OP00290, cps, cpsB, cpsGB | |||||||||
| Gene(s): | wcaB, wcaA, wzc, wzb, wza Genome Browser M3D Gene expression COLOMBOS | |||||||||
| Reference(s): |
[2] Ebel W., et al., 1999 [3] Stout V. 1996 |
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| Promoter | ||||||||||
| Name: | wzap1 | |||||||||
| +1: | 2137583 | |||||||||
| Sigma Factor: | Sigma70 Sigmulon | |||||||||
| Distance from start of the gene: | 340 | |||||||||
| Sequence: |
atagccaattaccgaattgttatcttgcctgctattccgttagctgtaacacttcctcctGcattattggaaagccaatat -35 -10 +1 |
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| Evidence: |
[HIPP] [ICWHO] [IHBCE] [TIM] |
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| Reference(s): |
[4] Huerta AM., et al., 2003 [3] Stout V. 1996 |
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| Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
|---|---|---|---|---|---|---|---|---|---|---|
| LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
| proximal | RcsAB | activator | wzap1 | 2137659 | 2137673 | -83.0 | taaaaaccatATTGAATGACACTTAatataattct | nd | [GEA], [AIBSCS] | [2] |
| remote | RcsAB | activator | wzap1 | 2137681 | 2137695 | -105.0 | attgtcaaccTAAAGAAACTCCTAAaaaccatatt | nd | [BPP], [SM] | [3], [5], [6] |
| RNA cis-regulatory element | |
|---|
| Regulation, transcriptional elongation | |
| Attenuator type: | Translational |
| Strand: | reverse |
| Evidence: | [ICA] Inferred by computational analysis |
| Reference(s): | [7] Merino E, et al., 2005 |
| Structure type | Energy | LeftPos | RightPos | Sequence (RNA-strand) | |
|---|---|---|---|---|---|
| terminator | -10.3 | 2133408 | 2133437 | tcacgccgcaTCCGGCAAGCAAACCAGCTCATAAGCCGGgagaacaacc |
| Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos" |
| REGULATION, RNA cis-regulatory element: | |
| Rfam type: | Cis-reg |
| Strand: | reverse |
| Evidence: | [ICA] Inferred by computational analysis |
| Reference(s): | [8] null null |
| Description | Rfam score | Left Pos | Right Pos | Sequence (RNA-strand) | |
|---|---|---|---|---|---|
| JUMPstart RNA | 57.3 | 2137422 | 2137460 | uaaacuaaauCAGUGUAUUGGUAGCUAAAAAGCCAGGGGCGGUAGCGUGucuggaugcc |
| Notes: "The provied "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appears as the reverse complement of the sequence delimited by LeftPos-RightPos" |
| Reference(s) |
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|---|---|
[AIBSCS] Automated inference based on similarity to consensus sequences