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Name: | ascFB | |||||||||
Gene(s): | ascF, ascB Genome Browser M3D Gene expression COLOMBOS | |||||||||
Note(s): | ascFB is a cryptic operon that is transcribed divergently from ascG. This cryptic operon is activated by the insertion of IS186 into the ascG (repressor) gene (but that activation is readily reversible by precise excision of IS186). Hall and Xu (1992) reported the complete nucleotide sequence of the asc operon and the mechanism by which the cryptic operon is activated. They also mentioned that ascFB is paralogous (homologous via a gene duplication) to bglFB, and ascG is paralogous to galR Hall BG,1992 Modifications (duplications of 10 nt) in the intergenic regions between ascF and ascB modulate transcription of ascB and the growth rate on cellobiose minimal medium Parisutham V,2015. Datsenko KA, Wanner BL,2000 |
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Reference(s): | [1] Hall BG., et al., 1992 | |||||||||
Promoter | ||||||||||
Name: | ascFp | |||||||||
+1: | 2839429 | |||||||||
Sigma Factor: | Sigma70 Sigmulon | |||||||||
Distance from start of the gene: | 95 | |||||||||
Sequence: |
ataaaaaatgaacaattcactctcttgcttatttagtgacaactattcatgattttgtgaAaccggtttcttaattccgtt -35 -10 +1 |
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Evidence: |
[AIPP] [ICWHO] [TIM] |
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Reference(s): |
[1] Hall BG., et al., 1992 [2] Huerta AM., et al., 2003 [3] Ishida Y., et al., 2009 |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
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LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | AscG | repressor | ascFp | 2839350 | 2839364 | -72.5 | aaaatattcaGGTGACCGGTTTCACaaatataaaa | nd | [GEA], [AIBSCS], [BPP] | [1], [3] |
proximal | AscG | repressor | ascFp | 2839426 | 2839440 | 4.5 | catgattttgTGAAACCGGTTTCTTaattccgttt | nd | [GEA], [AIBSCS], [BPP] | [3] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | CRP-cyclic-AMP | activator | ascFp | 2839347 | 2839368 | -71.5 | ggaaaaatatTCAGGTGACCGGTTTCACAAATataaaaaatg | nd | [BPP], [ICWHO] | [3] |
Name: | ascB |
Gene(s): | ascB Genome Browser M3D Gene expression COLOMBOS |
Note(s): | Modifications (duplications of 10 nt) in the intergenic regions between ascF and ascB modulate transcription of ascB and the growth rate on cellobiose minimal medium Parisutham V,2015. Datsenko KA, Wanner BL,2000 Sequence similarities suggest that the asc operon is probably a duplication of the bgl operon Hall BG,1992 |
Evidence: | [BTEI] Boundaries of transcription experimentally identified |
Reference(s): | [4] Parisutham V., et al., 2015 |
Promoter | |
Name: | ascBp |
+1: | 2840942 |
Distance from start of the gene: | 48 |
Sequence: |
gctcggctttgaggatattcctgttgaggaagcggctgcccaggcgcgaaagtatcagagCgtacaaccgaccgtcgccaa |
Evidence: | [TIM] |
Reference(s): | [4] Parisutham V., et al., 2015 |
Reference(s) |
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